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References
Maizel, J.V., White, D.O. & Scharff, M.D. The polypeptides of adenovirus. I. Evidence for multiple protein components in the virion and a comparison of types 2, 7A, and 12. Virology 36, 115–125 (1968).
Horwitz, M.S. in Virology (eds. Fields, B.N. et al.) Vol. 2, 1679–1721 (Raven, New York, 1990).
Schneider, M.D. & French, B.A. The advent of adenovirus. Gene therapy for cardio vascular disease. Circulation 88, 1937–1941 (1993).
Goodman, J.C. et al. Adenoviral-mediated thymidine kinase gene transfer into the primate brain followed by systemic ganciclovir: Pathologic, radiologic and molecular studies. Hum. Gene Ther. 7, 1241–1250 (1996).
Crystal, R.G. et al. Administration of an adenovirus containing the human CFTR cDNA to the respiratory tract of individuals with cystic fibrosis. Nature Genet. 8, 42–51 (1994).
Durham, H.D. et al. Toxicity of replication-defective adenoviral recombinants in dissociated cultures of nervous tissue. Exp. Neurol. 140, 14–20 (1996).
Toloza, E.M. et al. In vivo cancer gene therapy with a recombinant lnterleukin-2 adenovirus vector. Cancer Gene Ther. 3, 11–17 (1996).
Schulick, A.H., Newman, K.D., Virmani, R. & Dichek, D.A. In vivo gene transfer into injured carotid arteries. Optimization and evaluation of acute toxicity. Circulation 91, 2407–2414 (1995).
Simon, R.H. et al. Adenovirus-mediated transfer of the CFTR gene to lung of non-human primates: Toxicity study. Hum. Gene Ther. 4, 771–780 (1993).
Chuck, A.S., Clarke, M.F. & Palsson, B.O. Retroviral infection is limited by Brownian motion. Hum. Gene Ther. 6, 1527–1534 (1996).
Allison, A.C. & Valentine, R.C. Virus particle adsorption. III. Adsorption of viruses by cell monolayers and effects of some variables on adsorption. Biochim. Biophys. Acta 40, 400–410 (1959).
Strayer, D.S. et al. Titer replication-defective virus for use in gene transfer. BioTechniques 22, 447–450 (1997).
Mittereder, N., March, K.L. & Trapnell, B.C. Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy. J. Virol. 70, 7498–7509 (1996).
Trapnell, B.C. Considerations for the determination of adenovirus vector particle concentration and infectivity. Natcher Conf. Center Proc. 1, 59 (1996).
Van Holde, K.E. Physical Biochemistry (Prentice Hall, Englewood Cliffs, New Jersey, 1971).
Huyghe, B.G. et al. Purification of a type 5 recombinant adenovirus encoding human p53 by column chromatography. Hum. Gene Ther. 6, 1403–1416 (1995).
Kotani, H. et al. Improved methods of retroviral vector transduction and production for gene therapy. Hum. Gene Ther. 5, 19–28 (1994).
Oliver, C.J., Shortridge, K.F. & Belyavin, G. Diffusion coefficient and molecular weight of type 5 adenovirus by photon-correlation spectroscopy. Biochim. Biophys. Acta 437, 589–598 (1976).
Marshall, A.G. Biophysical Chemistry, Principles, Techniques and Applications (John Wiley, New York, 1975).
Winters, W.D. & Russell, W.C. Studies on the assembly of adenovirus in vitro. J. Gen. Virol. 10, 181–194 (1971).
McAllister, R.M., Goodheart, C.R., Mirabal, V.Q. & Huebner, R.J. Human adenoviruses: Tumor production in hamsters by types 12 and 18 grown from single plaques. PSEBM 122, 455–458 (1966).
Graham, F.L. & Prevec, L. in Methods in Molecular Biology (ed. Murray, E.J.) 109–128 (Humana Press, Clifton, New Jersey, 1991).
Kochanek, S. et al. A new adenoviral vector: Replacement of all viral coding se quences with 28 kb of DNA independently expressing both full-length dystrophin and beta-galactosidase. Proc. Natl. Acad. Sci. USA 93, 5731–5736 (1996).
Green, M. & Pina, M. Biochemical studies on adenovirus multiplication. IV. Isolation, purification, and chemical analysis of adenovirus. Virology 20, 199–207 (1963).
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Nyberg-Hoffman, C., Shabram, P., Li, W. et al. Sensitivity and reproducibility in adenoviral infectious titer determination. Nat Med 3, 808–811 (1997). https://doi.org/10.1038/nm0797-808
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DOI: https://doi.org/10.1038/nm0797-808
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