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Pseudomonic Acid: an Antibiotic produced by Pseudomonas fluorescens

Nature volume 234, pages 416–417 (1971)Cite this article

Abstract

THE antagonistic effects of Pseudomonas fluorescens were first recorded by Garre1 in 1887. Several reports since have dealt with the biological activity of cultures and extracts of P. fluorescens2. We wish to report the production and purification of these inhibitory substances and the characterization of a metabolite responsible for a significant proportion of the antibacterial activity.

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References

  1. Baader, A., and Garre, C., Corresp.-Bl. Schweiz. Aerzte, 17, 385 (1887).

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  2. Florey, H. W., Chain, E. B., Heatley, N. G., Jennings, M. A., Saunders, A. G., Abraham, E. P., and Florey, M. E., Antibiotics, I, 554 (Oxford University Press, 1949).

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  3. Polyakova, S. G., and Belov, V. N., Zh. Obshch. Khim., 34, 565 (1964).

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Authors and Affiliations

  1. Department of Biochemistry, Imperial College of Science and Technology, London, SW7

    A. T. FULLER, G. MELLOWS, M. WOOLFORD, G. T. BANKS, K. D. BARROW & E. B. CHAIN

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  1. A. T. FULLER
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  2. G. MELLOWS
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  3. M. WOOLFORD
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  4. G. T. BANKS
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  5. K. D. BARROW
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  6. E. B. CHAIN
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FULLER, A., MELLOWS, G., WOOLFORD, M. et al. Pseudomonic Acid: an Antibiotic produced by Pseudomonas fluorescens. Nature 234, 416–417 (1971). https://doi.org/10.1038/234416a0

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  • DOI: https://doi.org/10.1038/234416a0

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