Abstract
Purpose of Review
Peripheral nerve blocks of the scalp, mainly greater occipital nerve blocks, have received a renewed interest amongst pediatric providers as they offer an alternate option to provide both acute and chronic relief from the suffering of children with difficult to treat headaches. This narrative review will provide an in-depth discussion of the published pediatric-specific studies exploring the utility of nerve blocks for pediatric headache disorders.
Recent Findings
A total of seven pediatric publications have been reported to date and reveal excellent therapeutic effectiveness of bilateral greater occipital nerve blocks on primary chronic headaches and post-traumatic headaches. Lidocaine is the preferred anesthetic choice and the value-added of concomitant steroids remains to be elucidated. It is important to ensure complete paresthesia of the blocked nerves to maximize effectiveness.
Summary
The available studies suggest that peripheral nerve blocks of the scalp are an excellent tool that frontline clinicians can add to their armamentarium in treating pediatric headaches.
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References
Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
Rome HP Jr, Rome JD. Limbically augmented pain syndrome (LAPS): kindling, corticolimbic sensitization, and the convergence of affective and sensory symptoms in chronic pain disorders. Pain Med. 2000;1(1):7–23.
•• Blumenfeld A, Ashkenazi A, Napchan U, Bender SD, Klein BC, Berliner R, et al. Expert consensus recommendations for the performance of peripheral nerve blocks for headaches—a narrative review. Headache. 2013;53(3):437–46. Review article summarizing indications of peripheral nerve blocks of the scalp in adults
Tobin J, Flitman S. Occipital nerve blocks: when and what to inject? Headache. 2009;49:1521–33.
Ashkenazi A, Blumenfeld A, Napchan U, Narouze S, Grosberg B, Nett R, et al. Peripheral nerve blocks and trigger point injections in headache management—a systematic review and suggestions for future research. Headache. 2010;50(6):943–52.
Tang Y, Kang J, Zhang Y, Zhang X. Influence of greater occipital nerve block on pain severity in migraine patients: a systematic review and meta-analysis. Am J Emerg Med. 2017 https://doi.org/10.1016/j.ajem.2017.08.027.
Ashkenazi A, Matro R, Shaw JW, Abbas MA, Silberstein SD. Greater occipital nerve block using local anaesthetics alone or with triamcinolone for transformed migraine: a randomised comparative study. J Neurol Neurosurg Psychiatry. 2008;79(4):415–7.
Dilli E, Halker R, Vargas B, Hentz J, Radam T, Rogers R, et al. Occipital nerve block for the short-term preventive treatment of migraine: a randomized, double-blinded, placebo-controlled study. Cephalalgia. 2015;35(11):959–68.
Inan LE, Inan N, Karadas O, Gul HL, Erdemoglu AK, Turkel Y, et al. Greater occipital nerve blockade for the treatment of chronic migraine: a randomized, multicenter, double-blind, and placebo-controlled study. Acta Neurol Scand. 2015;132(4):270–7.
•• Gelfand AA, Reider AC, Goadsby PJ. Outcomes of greater occipital nerve injections in pediatric patients with chronic primary headache disorders. Pediatr Neurol. 2014;50(2):135–9. Pediatric study of nerve blocks for chronic migraines
Lacey DJ. Efficacy of greater occipital nerve blocks (ONBs) in the treatment of chronic daily headaches (CDH) in adolescent females with fibromyalgia. Headache. 2014;54:26–7.
Renaudon-Smith ETC, Goadsby P, Prabhakar P. Greater occipital nerve injection (GONI) for chronic headache in children. J Headache and Pain. 2010;11(Suppl 1):76.
Zemek R, Barrowman N, Freedman SB, Gravel J, Gagnon I, McGahern C, et al. Clinical risk score for persistent postconcussion symptoms among children with acute concussion in the ED. JAMA. 2016;315(10):1014–25.
•• Dubrovsky S, Friedman D, Kocilowicz H. Pediatric post-traumatic headaches and peripheral nerve blocks of the scalp: a case series and patient satisfaction survey. Headache. 2014;54(5):878–87. Pediatric study of nerve blocks for post-concussion headaches
•• Seeger TA, Orr S, Bodell L, Lockyer L, Rajapakse T, Barlow KM. Occipital nerve blocks for pediatric posttraumatic headache: a case series. J Child Neurol. 2015;30(9):1142–6. Pediatric study of nerve blocks for post-concussion headaches
Zaremski JL, Hurley RW, Herman D, Bauer RM, Ahn AH. Occipital neuralgia blockade as a treatment after concussions. A case series. PM and R. 2014;1:S249.
Mumber HE, Szperka C. Retrospective study of nerve blocks for the treatment of headaches in children and adolescents. Headache. 2016;56:37.
• Szperka CL, Gelfand AA, Hershey AD. Patterns of use of peripheral nerve blocks and trigger point injections for pediatric headache: results of a survey of the American Headache Society Pediatric and Adolescent Section. Headache. 2016;56(10):1597–607. Survey study of American headache experts on their use of nerve blocks for headaches
Guvencer M, Akyer P, Sayhan S, Tetik S. The importance of the greater occipital nerve in the occipital and the suboccipital region for nerve blockade and surgical approaches--an anatomic study on cadavers. Clin Neurol Neurosurg. 2011;113(4):289–94.
Loukas M, El-Sedfy A, Tubbs RS, Louis RG Jr, Wartmann CH, Curry B, et al. Identification of greater occipital nerve landmarks for the treatment of occipital neuralgia. Folia Morphol (Warsz). 2006;65(4):337–42.
Bartsch T, Goadsby PJ. Increased responses in trigeminocervical nociceptive neurons to cervical input after stimulation of the dura mater. Brain. 2003;126(Pt 8):1801–13.
Busch V, Jakob W, Juergens T, Schulte-Mattler W, Kaube H, May A. Functional connectivity between trigeminal and occipital nerves revealed by occipital nerve blockade and nociceptive blink reflexes. Cephalalgia. 2006;26(1):50–5.
Natsis K, Baraliakos X, Appell HJ, Tsikaras P, Gigis I, Koebke J. The course of the greater occipital nerve in the suboccipital region: a proposal for setting landmarks for local anesthesia in patients with occipital neuralgia. Clin Anat. 2006;19(4):332–6.
Ward JB. Greater occipital nerve block. Semin Neurol. 2003;23(1):59–62.
Misra UK, Kalita J, Tripathi G, Bhoi SK. Role of beta endorphin in pain relief following high rate repetitive transcranial magnetic stimulation in migraine. Brain Stimul. 2017;10(3):618–23.
Karadas O, Ozon AO, Ozcelik F, Ozge A. Greater occipital nerve block in the treatment of triptan-overuse headache: a randomized comparative study. Acta Neurol Scand. 2017;135(4):426–33.
Acknowledgement
Special acknowledgment to the late Dr Rubin Dubrovsky, who inspired me to treat patients and their families suffering with acute and chronic pain, with an empathetic and pragmatic approach.
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Alexander Sasha Dubrovsky declares no conflict of interest.
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This article is part of the Topical Collection on Childhood and Adolescent Headache
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Dubrovsky, A.S. Nerve Blocks in Pediatric and Adolescent Headache Disorders. Curr Pain Headache Rep 21, 50 (2017). https://doi.org/10.1007/s11916-017-0650-8
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DOI: https://doi.org/10.1007/s11916-017-0650-8