Abstract
Developmental dysplasia of the hip is a medical term representing the hip joint instability that appears mainly in infants. The assessment metric of physician is based on the femoral head coverage rate, which needs to segment the femoral head area in 2D ultrasound images. In this paper, we propose an approach to automatically segment the femoral head. The proposed method consists of two parts, firstly, mean filtering, morphological processing and least squares operation are used to detect the ilium and acetabular bone baseline to coarsely obtain the region of interest of the femoral head, then followed by an improved fully convolutional neural network named FNet which integrates the convolution encoder–decoder architecture, pooling indices and residual connection operation for more accurate segmentation. FNet is trained in a cascaded way, which can help the network learn more features with a limited dataset and thus further improve the segmentation performance. Experimental results show that the proposed method achieved an average dice, recall and IoU value of 0.946, 0.937 and 0.897. Moreover, the features learned by convolutional layers are visualized to demonstrate that FNet can focus on significant features, which is helpful to restore the contour of the femoral head more precisely. In conclusion, the proposed method is capable of segmenting femoral head accurately and guiding the diagnosis of developmental dysplasia of the hip.
Similar content being viewed by others
References
Kocer, H.E., Cevik, K.K., Sivri, M., et al.: Measuring the effect of filters on segmentation of developmental dysplasia of the hip. Iran. J. Radiol. 13(3), 1–10 (2016)
Tosun, H.B., Bulut, M., Karakurt, L., Belhan, O., Serbest, S.: Evaluation of the results of hip ultrasonography which applied for screening of developmental hip dysplasia. Fırat Med. J. 15(4), 178–183 (2010)
de Luis-Garcia, R., Aja-Fernandez, S., Cardenes-Almeida, R., et al.: Analysis of ultrasound images based on local statistics. Application to the diagnosis of developmental dysplasia of the hip. In: Presented at IEEE Ultrasonics Symposium (2007)
Bonny, S., Chanu, Y.J., Singh, K.M.: Speckle reduction of ultrasound medical images using Bhattacharyya distance in modified non-local mean filter. SIViP 13(2), 299–305 (2019)
Al-Bashir, A.K., Al-Abed, M., Sharkh, F.M.A., et al.: Algorithm for automatic angles measurement and screening for developmental dysplasia of the hip (DDH). In: Presented at the 37th Annual International Conference of the IEEE, Engineering in Medicine and Biology Society (EMBC) (2015)
Herring, J.A.: Developmental dysplasia of the hip. In: Herring, J.A. (ed.) Tachdjian’s Pediatric Orthopaedics, pp. 513–534. W.B. Saunders Co., Philadelphia (2003)
Graf, R.: The diagnosis of congenital hip dislocation by the ultrasound compound treatment. Arch. Orthop. Trauma Surg. 97(3), 117–133 (1980)
Graf, R.: Classification of hip joint dysplasia by means of sonography. Arch. Orthop. Trauma Surg. 102(4), 248–255 (1984)
Tang, M., Zhang, Z., Cobzas, D., et al.: Segmentation-by-detection: a cascade network for volumetric medical image segmentation. In: Presented at IEEE 15th International Symposium on Biomedical Imaging (2018)
Chandra, S.S., Xia, Y., Engstrom, C., et al.: Focused shape models for hip joint segmentation in 3D magnetic resonance images. Med. Image Anal. 18(3), 567–578 (2014)
Cen, G., Cai, N., Wu, J., et al.: Detonator coded character spotting based on convolutional neural networks. Signal Image Video Process. (2019). https://doi.org/10.1007/s11760-019-01525-1
Fan, S., Wang, R., Wu, Z., et al.: High-speed tracking based on multi-CF filters and attention mechanism. Signal Image Video Process. (2019). https://doi.org/10.1007/s11760-019-01527-z
Feng, X., Yao, H., Zhang, S.: An efficient way to refine DenseNet. Signal Image Video Process. 13, 1–7 (2019)
Mithra, K.S., Emmanuel, W.R.S.: Automated identification of mycobacterium bacillus from sputum images for tuberculosis diagnosis. Signal Image Video Process. 13, 1–8 (2019)
Nezamabadi, K., Naseri, Z., Moghaddam, H.A., et al.: Lung HRCT pattern classification for cystic fibrosis using convolutional neural network. Signal Image Video Process. 13, 1–8 (2019)
Prasoon, A., Petersen, K., Igel, C., Lauze, F., Dam, E., Nielsen, M.: Deep feature learning for knee cartilage segmentation using a triplanar convolutional neural network. In: Presented at International Conference on Medical Image Computing and Computer-Assisted Intervention (2013). https://doi.org/10.1007/978-3-642-40763-5_31
Ronneberger, O., Fischer, P., Brox, T.: U-net: convolutional networks for biomedical image segmentation. In: Presented at International Conference on Medical Image Computing and Computer-Assisted Intervention (2015). https://doi.org/10.1007/978-3-319-24574-4_28
Stollenga, M.F., Byeon, W., Liwicki, M., Schmid-huber, J.: Parallel multi-dimensional LSTM, with application to fast biomedical volumetric image segmentation. In: Presented at Advances in Neural Information Processing Systems (2015). http://papers.nips.cc/paper/5642-parallel-multi-dimensional-lstm-with-application-to-fast-biomedical-volumetric-image-segmentation. Accessed 28 Aug 2019
Roth, H.R., Lu, L., Farag, A., Shin, H.-C., Liu, J., Turkbey, E. B., Summer, R.M.: Deeporgan: multi-level deep convolutional networks for automated pancreas segmentation. In: Presented at International Conference on Medical Image Computing and Computer-Assisted Intervention (2015). https://doi.org/10.1007/978-3-319-24553-9_68
Çiçek, Ö., Abdulkadir, A., Lienkamp, S.S., Brox, T., Ronneberger, O.: 3D U-Net: learning dense volumetric segmentation from sparse annotation. In: Presented at International Conference on Medical Image Computing and Computer-Assisted Intervention (2016). https://doi.org/10.1007/978-3-319-46723-8_49
Havaei, M., Davy, A., Warde-Farley, D., Biard, A., Courville, A., Bengio, Y., Pal, C., Jodoin, P.-M., Larochelle, H.: Brain tumor segmentation with deep neural networks. Med. Image Anal. 35, 18–31 (2017)
Chen, H., Dou, Q., Yu, L., Qin, J., Heng, P.-A.: Voxresnet: deep voxelwise residual networks for brain segmentation from 3D MR images. NeuroImage 170, 446–455 (2017)
Badrinarayanan, V., Handa, A., Cipolla, R.: SegNet: a deep convolutional encoder-decoder architecture for robust semantic pixel-wise labelling. arXiv preprint arXiv:1505.07293 (2015)
He, K., Zhang, X., Ren, S., et al.: Deep residual learning for image recognition. In: Presented at Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (2016). https://www.cv-foundation.org/openaccess/content_cvpr_2016/html/He_Deep_Residual_Learning_CVPR_2016_paper.html. Accessed 28 Aug 2019
Nair, V., Hinton, G.E.: Rectified linear units improve restricted Boltzmann machines. In: Presented at Proceedings of the 27th International Conference on Machine Learning (ICML-10) (2010). https://www.cs.toronto.edu/~hinton/absps/reluICML.pdf. Accessed 28 Aug 2019
Ioffe, S., Szegedy, C.: Batch normalization: accelerating deep network training by reducing internal covariate shift. arXiv preprint: arXiv:1502.03167 (2015)
Dunlap, J.: Queue-linear flood fill: a fast flood fill algorithm. http://www.codeproject.com/KB/GDI-plus/queuelinearfloodfill.aspx. Accessed 28 Aug 2019
Chollet, F.: Keras: deep learning library for theano and tensorflow, vol. 7, no. 8 (2015). https://keras.io/k. Accessed 28 Aug 2019
Abadi, M., Barham, P., Chen, J., et al.: Tensorflow: a system for large-scale machine learning. In: Presented at OSDI (2016). https://www.usenix.org/system/files/conference/osdi16/osdi16-abadi.pdf. Accessed 28 Aug 2019
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. (2014). https://arxiv.org/abs/1412.6980
Milletari, F., Navab, N., Ahmadi, S. A.: V-net: fully convolutional neural networks for volumetric medical image segmentation. In: Presented at IEEE Fourth International Conference on 3D Vision (2016). https://ieeexplore.ieee.org/abstract/document/7785132/. Accessed 28 Aug 2019
Noh, H., Hong, S., Han, B.: Learning deconvolution network for semantic segmentation. In: Presented at Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition (2015)
Acknowledgements
We would like to thank the Shenzhen Children’s Hospital for providing data to support this project. This work was supported by National Key R&D Program of China (2017YFC0110700), National Natural Science Foundation of China (61771056), Key projects of Beijing Natural Science Foundation (4161004) and Beijing Science and Technology Plan Project (Z161100000216143, Z171100000117001).
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Chen, L., Cui, Y., Song, H. et al. Femoral head segmentation based on improved fully convolutional neural network for ultrasound images. SIViP 14, 1043–1051 (2020). https://doi.org/10.1007/s11760-020-01637-z
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11760-020-01637-z