Abstract
The significance of the preprocessing stage in any data mining task is well known. Before attempting medical data classification, characteristics ofmedical datasets, including noise, incompleteness, and the existence of multiple and possibly irrelevant features, need to be addressed. In this paper, we show that selecting the right combination of preprocessing methods has a considerable impact on the classification potential of a dataset. The preprocessing operations considered include the discretization of numeric attributes, the selection of attribute subset(s), and the handling of missing values. The classification is performed by an ant colony optimization algorithm as a case study. Experimental results on 25 real-world medical datasets show that a significant relative improvement in predictive accuracy, exceeding 60% in some cases, is obtained.
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Pham H N A, Triantaphyllou E. An application of a new metaheuristic for optimizing the classification accuracy when analyzing some medical datasets. Expert Systems with Applications, 2009, 36: 9240–9249
Almuhaideb S, El-Bachir Menai M. Hybrid metaheuristics for medical data classification. In: El-Ghazali T, ed. Hybrid Metaheuristics. Springer, 2013, 187–217
Penã-Reyes C A, Sipper M. Evolutionary computation in medicine: an overview. Artificial Intelligence in Medicine, 2000, 19(1): 1–23
Tanwani A K, Afridi J, Shafiq M Z, Farooq M. Guidelines to select machine learning scheme for classification of biomedical datasets. In: Pizzuti C, Ritchie M D, Giacobini M, eds. Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics. Springer, 2009, 28–139
Almuhaideb S, El-Bachir Menai M. A new hybrid metaheuristic for medical data classification. International Journal of Metaheuristics, 2014, 3(1): 59–80
Milne D, Witten I H. An open-source toolkit for mining Wikipedia. Artificial Intelligence, 2013, 194: 222–239
Alcalá-fdez J, L. Sánchez L, García S, del Jesus MJ, Ventura S, Garrell J M, Otero J, Bacardit J, Rivas V M, Fernández J C, Herrera F. KEEL: a software tool to assess evolutionary algorithms to data mining problems. Soft Computing, 2009, 13(3): 307–318
Martens D, de Backer M, Haesen R, Vanthienen J, Snoeck M, Baesens B. Classification with ant colony optimization. IEEE Transactions on Evolutionary Computation, 2007, 11(5): 651–665
Tanwani A K, Farooq M. Performance evaluation of evolutionary algorithms in classification of biomedical datasets. In: Proceedings of the 11th Annual Conference Companion on Genetic and Evolutionary Computation: Late Breaking Papers. 2009, 2617–2624
Tanwani A K, Farooq M. The role of biomedical dataset inclassification. In: Proceedings of Conference on Artificial Intelligence in Medicine in Europe. 2009
Tanwani A K, Farooq M. Classification potential vs. classification accuracy: a comprehensive study of evolutionary algorithms with biomedical datasets. Learning Classifier System, 2010: 127–144
Kotsiantis S B. Feature selection for machine learning classification problems: a recent overview. Artificial Intelligence Review, 2011: 249–268
Whitney A W. A direct method of nonparametric measurement selection. IEEE Transactions on Computers, 1971, 20(9): 1100–1103
Marill T, Green D. On the effectiveness of receptors in recognition systems. IEEE Transactions on Information Theory, 1963, 9(1): 11–17
Pudil P, Novovicová J, Kittler J. Floating search methods in features election. Pattern Recognition Letters, 1994, 15(10): 1119–1125
Yusta S C. Different metaheuristic strategies to solve the feature selection problem. Pattern Recognition Letters, 2009, 30(5): 525–534
Jourdan L, Dhaenens C, Talbi E G. A genetic algorithm for features election in datamining for genetics. In: Proceedings of the 4th Metaheuristics International Conference Porto. 2010: 29–34
Huang J J, Cai Y Z, Xu X M. A hybrid genetic algorithm for features election wrapper based on mutual information. Pattern Recognition Letters, 2007, 28(13): 1825–1844
AI-Ani A. Feature subset selection using ant colony optimization. International Journal of Computational Intelligence, 2005, 2(1): 53–58
Unler A, Murat A. A discrete particle swarm optimization method for feature selection in binary classification problems. European Journal of Operational Research, 2010, 206(3): 528–539
Bekkerman R, El-Yaniv R, Tishby N, Winter Y. Distributional word clusters vs. words for text categorization. Journal of Machine Learning Research, 2003, 3: 1183–1208
Liu H, Yu L. Toward integrating feature selection algorithms for classification and clustering. IEEE Transactions on Knowledge Discovery and Data Engineering, 2005, 17(4): 491–502
Shin K, Fernandes D, Miyazaki S. Consistency measures for features election: a formal definition, relative sensitivity comparison, and a fast algorithm. In: Proceedings of International Conference on Artificial Intelligence (IJCAI). 2011, 1491–1497
Kerber R. ChiMerge: discretization of numeric attributes. In: Proceedings of the 10th National Conference on Artificial Intelligence. 1992, 123–128
Liu H, Setiono R. Feature selection via discretization. IEEE Transactions on Knowledge and Data Engineering, 1997, 9(4): 642–645
Fayyad U M, Irani K B. Multi-interval discretization of continuousvalued attributes for classification learning. In: Proceedings of International Conference on Artificial Intelligence. 1993, 1022–1029
Jin R M, Breitbart Y, Muoh C. Data discretization unification. Knowledge and Information Systems, 2009, 19(1): 1–29
Quinlan R. C4.5: Programs for Machine Learning. San Mateo, CA: Morgan Kaufmann Publishers, 1993
Guyon I, Elisseeff A. An introduction to variable and feature selection. The Journal of Machine Learning Research, 2003, 3: 1157–1182
Kohavi R, John G H. Wrappers for feature subsets election. Artificial Intelligence, 1997, 97(1–2): 273–324
Caruana R, Freitag D. Greedy attribute selection. In: Proceedings of International Conference on Machine Learning. 1994, 28–36
Koza J R. Genetic Programming: On the Programming of Computers by Means of Natural Selection. Cambridge, MA: MIT Press, 1992
Breiman L, Friedman J H, Olshen R A, Stone C J. Classification and Regression Trees. New York, NY: Chapman & Hall, 1984
Das S. Filters, wrappers and a boosting-based hybrid for feature selection. In: Proceedings of International Conference on Machine Learning. 2001, 74–81
Han J W, Kamber M. Data Mining: Concepts and Techniques. 2nd edition. London, UK: Morgan Kaufmann Publishers, 2006
Chlebus B S, Nguyen S H. On finding optimal discretizations for two attributes. In: Polkowski L, Skowron A, eds. Rough Sets and Current Trends in Computing. Springer, 1998, 537–544
García S, Luengo J, Sáez J A, López V, Herrera F. A survey of discretization techniques: taxonomy and empirical analysis in supervised learning. IEEE Transactions on Knowledge and Data Engineering, 2013, 25(4): 734–750
Wong A K C, Chiu D K Y. Synthesizing statistical knowledge from incomplete mixed-mode data. IEEE Transactions on Pattern Analysis and Machine Intelligence, 1987, 9(6): 796–805
Garcá-Laencina P J, Sancho-Gómez J L, Figueiras-Vidal A R. Pattern classification with missing data: a review. Neural Computing and Applications, 2010, 19(2): 263–282
Grzymala-Busse JW, Goodwin L K, Grzymala-Busse WJ, Zheng X Q. Handling missing attribute values in preterm birth data sets. In: Slezak D, Yao J T, Peters J F, Ziarko W, Hu X H, eds. Rough Sets, Fuzzy Sets, Data Mining, and Granular Computing. Springer, 2005, 342–351
Batista G E A P A, Monard MC. An analysis of four missing data treatment methods for supervised learning. Applied Artificial Intelligence, 2003, 17(5–6): 519–533
Feng H H, Chen G S, Yin C, Yang B R, Chen Y M. A SVM regression based approach to filling in missing values. In: Khosla R, Howlett R J, Jain L C, eds. Knowledge-Based Intelligent Information and Engineering Systems. Springer, 2005, 581–587
Gupta A, Lam M S. Estimating missing values using neural networks. Journal of the Operational Research Society, 1996, 47(2): 229–238
Dempster A P, Laird N M, Rubin D B. Maximum likelihood from incomplete data via the EM algorithm. Journal of the Royal Statistical Society, Series B (Methodological), 1977, 39(1): 1–38
Schneider T. Analysis of incomplete climate data: estimation of mean values and covariance matrices and imputation of missing values. Journal of Climate, 2001, 14: 853–871
Gourraud P A, Génin E, Cambon-Thomsen A. Handling missing values in population data: consequences for maximum likelihood estimation of haplotype frequencies. European Journal of Human Genetics, 2004, 12: 805–812
Mcculloch W, Pitts W. A logical calculus of the ideas immanent in nervous activity. Bulletin of Mathematical Biophysics, 1943, 5: 115–133
Holland J H. Adaptation in Natural and Artificial Systems. Ann Arbor: The University of Michigan Press, 1975
Dorigo M. Optimization, learning and natural algorithms. Dissertation for the Doctoral Degree. Politecnico di Milano, Italy, 1992
Kennedy J, Eberhart R. Particle swarm optimization. In: Proceedings of IEEE International Conference on Neural Networks. 1995, 1942–1948
Sato T, Hagiwara M. Bee system: finding solution by a concentrated search. In: Proceedings of IEEE International Conference on Systems, Man, and Cybernetics. 1997
Karaboga D. An idea based on honey bee swarm for numerical optimization. Technical Report TR06, Erciyes University, 2005
Dorigo M, Gambardella L M. Ant colony system: a cooperative learning approach to the traveling salesman problem. IEEE Transactions on Evolutionary Computation, 1997, 1(1): 53–66
Parpinelli R S, Lopes H S, Freitas A A. Data mining with an ant colony optimization algorithm. IEEE Transactions Evolutionary Computation, 2002, 6(4): 321–332
Stützle T, Hoos H H. MAX-MIN ant system. Future Generation Computer Systems, 2000, 16(8): 889–914
Pellegrini P, Ellero A. The small world of pheromone trails. In: Dorigo M, Birattari M, Blum C, Clerc M, Stützle T, Winfield A F T, eds. Ant Colony Optimzation and Swarm Intelligence. Springer, 2008, 387–394
Cohen W W. Fast effective rule induction. In: Prieditis A, Russell S J, eds. International Conference on Machine Learning. Morgan Kaufmann, 1995, 115–123
Minnaert B, Martens D, de Baker M, Baesens B. To tune or not to tune: rule evaluation for metaheuristic-based sequential covering algorithms. Data Mining and Knowledge Discovery, 2015, 29(1): 237–272
Almuhaideb S, ElBachir Menai M. A new hybrid metaheuristic for medical data classification. International Journal of Metaheuristics, 2014: 1–17
Rissanen J. Modeling by shortest data description. Automatica, 1978, 14(5): 465–471
Kononenko I. On biases in estimating multi-valued attributes. In: Proceedings of International Conference on Artificial Intelligence. 1995, 1034–1040
Kira K, Rendell L A. A practical approach to feature selection. In: Proceedings of the 9th International Workshop on Machine Learning. 1992
Kononenko I. Estimating attributes: analysis and extensions of RELIEF. In: Proceedings of European Conference on Machine Learning. 1994, 171–182
Hall M A. Correlation-based feature selection for machine learning. Dissertation for the Dotoral Degree. Hamilton, New Zealand: University of Waikato, 1999
Liu H, Setiono R. A probabilistic approach to feature selection—a filter solution. In: Proceedings of International Conference on Machine Learning. 1996, 319–327
Frank E, Witten I H. Generating accurate rule sets without global optimization. In: Proceedings of the 15th International Conference on Machine Learning. 1998, 144–151
Holte R C. Very simple classification rules perform well on most commonly used datasets. Machine Learning, 1993, 11(1): 63–91
Klösgan W. Problems for knowledge discovery in databases and their treatment in the statistics interpreter explora. International Journal of Intelligent Systems, 1992, 7(7): 649–673
Janssen F, Fürnkranz J. On the quest for optimal rule learning heuristics. Machine Learning, 2010, 78(3): 343–379
Martens D, Baesens B, Fawcett T. Editorial survey: swarm intelligence for data mining. Machine Learning, 2010, 82(1): 1–42
Hanczara B, Dougherty E R. The reliability of estimated confidence intervals for classification error rates when only a single sample is available. Pattern Recognition, 2013, 64(3): 1067–1077
Kohavi R. A study of cross-validation and bootstrap for accuracy estimation and model selection. In: Proceedings of International Conference on Artificial Intelligence. 1995, 1137–1145
García S, Fernández A, Luengo J, Herrera F. A study of statistical techniques and performance measures for genetics-based machine learning: accuracy and interpretability. Soft Computing, 2009, 13(10): 959–977
Wilcoxon F. Individual comparisons by ranking methods. Biometrics Bulletin, 1945, 1(6): 80–83
Friedman M. The use of ranks to avoid the assumption of normality implicit in the analysis of variance. American Statistical Association, 1937, 32(200): 675–701
Frank A, Asuncion A. UCI machine learning repository. Irvine, CA: University of California, 2010
Napierala K, Stefanowski J. BRACID: a comprehensive approach to learning rules from imbalanced data. Journal of Intelligent Information Systems, 2012, 39(2): 335–373
Orriols-Puig A, Bernadó-Mansilla E. The class imbalance problem in UCS classifier system: a preliminary study. In: Proceedings of the 2003–2005 International Conference on Learning Classifier Systems. 2007, 161–180
Pazzani M J, Mani S, Shankle W R. Acceptance of rules generated by machine learning among medical experts. Methods of Information in Medicine, 2001, 40(5): 380–385
Vapnik V N. Estimation of Dependences Based on Empirical Data. Springer-Verlag, 1982
Vapnik V N. The Nature of Statistical Learning Theory. New York: Springer, 1995
Lim T S, Loh W Y, Shih Y S. A comparison of prediction accuracy, complexity, and training time of thirty-three old and new classification algorithms. Machine Learning, 2000, 40(3): 203–228
Gonzalez A, Perez R. Slave: a genetic learning system based on an iterative approach. IEEE Transactions on Fuzzy Systems, 1999, 7(2): 176–191
Bernadó-Mansilla E, Garrell-Guiu J M. Accuracy based learning classifier systems: models, analysis and applications to classification tasks. Evolutionary Computation, 2003, 11(3): 209–238
Wilson S W. Classifier fitness based on accuracy. Evolutionary Computation, 1995, 3(2): 149–175
Orriols-Puig A, Casillas J, Bernadó-Mansilla E. A comparative study of several geneticbased supervised learning systems. In: Bull L, Bernadó-Mansilla E, Holmes J H, eds. Learning Classifier Systems in Data Mining. Springer, 2008, 205–230
Troyanskaya O G, Cantor M, Sherlock G, Brown P O, Hastie T, Tibshirani R, Botstein D, Altman R B. Missing value estimation methods for DNA microarrays. Bioinformatics, 2001, 17(6): 520–525
Amaldi E, Kann V. On the approximability of minimizing nonzero variables or unsatisfied relations in linear systems. Theoretical Computer Science, 1998, 209(1–2): 237–260
Bacardit J, Butz M. Data mining in learning classifier systems: comparing XCS with gassist. In: Proceedings of International Conference on Learning Classifier Systems (IWLCS 2003–2005). 2004, 282–290
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Sarab Almuhaideb is a PhD student in the Department of Computer Science, King Saud University, Saudi Arabia. She is a lecturer in the Department of Computer Science, Prince Sultan University, Saudi Arabia. Her research interests include issues related to machine learning, evolutionary computation, and hybrid metaheuristics.
Mohamed El Bachir Menai received his PhD degree in computer science from Mentouri University of Constantine, Algeria, and University of Paris VIII, France in 2005. He also received a “Habilitation universitaire” in computer science from Mentouri University of Constantine, in 2007 (it is the highest academic qualification in Algeria, France and Germany). He is currently a professor in the Department of Computer Science at King Saud University, Saudi Arabia. His main interests include evolutionary computing, data mining, machine learning, natural language processing, and satisfiability problems.
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Almuhaideb, S., Menai, M.E.B. Impact of preprocessing on medical data classification. Front. Comput. Sci. 10, 1082–1102 (2016). https://doi.org/10.1007/s11704-016-5203-5
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DOI: https://doi.org/10.1007/s11704-016-5203-5