[go: up one dir, main page]
More Web Proxy on the site http://driver.im/ Skip to main content
Log in

Multiclass classification of Parkinson’s disease using different classifiers and LLBFS feature selection algorithm

  • Published:
International Journal of Speech Technology Aims and scope Submit manuscript

Abstract

Since approximately 90% of the people with PD (Parkinson’s disease) suffer from speech disorders including disorders of laryngeal, respiratory and articulatory function, using voice analysis disease can be diagnosed remotely at an early stage with more reliability and in an economic way. All previous works are done to distinguish healthy people from people with Parkinson’s disease (PWP). In this paper, we propose to go further by multiclass classification with three classes of Parkinson stages and healthy control. So we have used 40 features dataset, all the features are analyzed and 9 features are selected to classify PWP subjects in four classes, based on unified Parkinson’s disease Rating Scale (UPDRS). Various classifiers are used and their comparison is done to find out which one gives the best results. Results show that the subspace discriminant reach more than 93% overall classification accuracy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
£29.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price includes VAT (United Kingdom)

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

References

  • Baken R.J. & Orlikoff R.F. (2000). Clinical measurement of speech and voice (2nd ed.). San Diego: Singular Thomson Learning

    Google Scholar 

  • Chen, H.-L., Huang, C.-C., Yu, X.-G., Xu, X., Sun, X., Wang, G., & Wang, S. (2013). An efficient diagnosis system for detection of Parkinson’s disease using fuzzy k-nearest neighbor approach. Expert Systems with Applications, 40(1), 263–271.

    Article  Google Scholar 

  • Duffy, & Motor, R. J. (2005). Speech Disorders: Substrates, Differential Diagnosis and Management. (2nd ed.). St. Louis: Elsevier Mosby

    Google Scholar 

  • ENE MARIUS (2008). Neural network-based approach to discriminate healthy people from those with Parkinson’s disease. Annals of the University of Craiova, 35, 112–116.

    MathSciNet  MATH  Google Scholar 

  • Fraile, R., Saenz-Lechon, N., Godino-Llorente, J. I., Osma-Ruiz, V., & Fredouille, C. (2009). Automatic detection of laryngeal pathologies in records of sustained vowels by means of mel-frequency cepstral coefficient parameters and differentiation of patients by sex. Folia Phoniatrica et Logopaedica, 61, 146–152.

    Article  Google Scholar 

  • Godino-Llorente, J. I., Gomez-Vilda, P., & Blanco-Velasco, M. (2006). Dimensionality reduction of a pathological voice quality assessment system based on gaussian mixture models and short-term cepstral parameters. IEEE Transactions on Biomedical Engineering, 53, 1943–1953.

    Article  Google Scholar 

  • Hastie, T., Tibshirani, R., & Friedma, J. (2009). The elements of statistical learning: data mining, inference, and prediction (2nd ed.). Springer: New York

    Book  MATH  Google Scholar 

  • Ho, A., Iansek, R., Marigliani, C., Bradshaw, J., & Gates, S. (1998). Speech impairment in a large sample of patients with Parkinson’s disease. Behavioral Neurology, 11, 131–137.

    Article  Google Scholar 

  • Lee, S.-H., & Lim, J.S. (2012). Parkinson’s disease classification using gait characteristics and wavelet-based feature extraction, Expert Systems with Applications, 39(8), 7338–7344.

    Article  Google Scholar 

  • Little, M. A., McSharry, P. E., Hunter, E. J., Spielman, J., & Ramig, L. O. (2009). Suitability of dysphonia measurements for telemonitoring of Parkinson’s disease. IEEE Transactions Biomedical Engineering, 56(4), 1015–1022.

    Article  Google Scholar 

  • Logemann, J. A., Fisher, H. B., Boshses, B., & Blonsky, E. R. (1978). Frequency and co-occurrence of vocal-tract dysfunctions in speech of a large sample of parkinson patients. Journal of Speech Hearing Disorder, 43, 47–57.

    Article  Google Scholar 

  • Michie, D., Spiegelhalter, D.J., & Taylor, C. C. (Eds.), (1994). Machine learning, neural and statistical classification. Ellis Horwood, 1994. Retrieved from http://www1.maths.leeds.ac.uk/~charles/statlog/).

  • Patient Voice Analysis (PVA) Synapse ID: syn2321745 https://www.synapse.org.

  • Rahn, D. A., Chou, M., Jiang, J. J. & Zhang, Y. (2007). Phonatory impairment in Parkinson’s disease: Evidence from nonlinear dynamic analysis and perturbation analysis. Journal of Voice, 21, 64–71.

    Article  Google Scholar 

  • Sapir, S., Spielman, J. L., Ramig, L. O., Story, B. H., & Fox, C. (2007). Effects of intensive voice treatment (the Lee Silverman Voice Treatment [LSVT]) on vowel articulation in dysarthric individuals with idiopathic Parkinson Disease: acoustic and perceptual findings. Journal of Speech Lang Hearing Research, 50, 899–912. doi:10.1044/1092-4388. (2007/064).

    Article  Google Scholar 

  • Sun, Y., Todorovic, S., & Goodison, S. (2010). Local learning based feature selection for high dimensional data analysis, IEEE Pattern Analysis and Machine Intelligence, 32(9), 1610–1626.

    Google Scholar 

  • Titze, I. R. (2000). Principles of Voice Production. (2nd ed.) Iowa City, US: National Center for Voice and Speech

    Google Scholar 

  • Tsanas, A. (2012). Accurate telemonitoring of Parkinson’s disease symptom severity using nonlinear speech signal processing and statistical machine learning, D. Phil. (Ph.D.) thesis. UK: University of Oxford.

    Google Scholar 

  • Tsanas, A. (2013). “Automatic objective biomarkers of neurodegenerative disorders using nonlinear speech signal processing tools”, 8th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA), pp. 37–40, Florence, Italy, 16–18 December.

  • Tsanas, A., Little, M. A., McSharry, P. E., & Ramig, L. O. (2011). “Nonlinear speech analysis algorithms mapped to a standard metric achieve clinically useful quantification of average Parkinson’s disease symptom severity”. Journal of the Royal Society Interface, 8, 842–855.

    Article  Google Scholar 

  • Vapnik, V. (1995). The nature of statistical learning theory. New York: Springer.

    Book  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Elmehdi Benmalek.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Benmalek, E., Elmhamdi, J. & Jilbab, A. Multiclass classification of Parkinson’s disease using different classifiers and LLBFS feature selection algorithm. Int J Speech Technol 20, 179–184 (2017). https://doi.org/10.1007/s10772-017-9401-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10772-017-9401-9

Keywords