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Normative data for the ACE-R in an Italian population sample

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Abstract

The Addenbrooke’s Cognitive Examination Revised (ACE-R) is a brief cognitive screening instrument also proposed to detect mild cognitive impairment, a high-risk condition for Alzheimer’s disease and other forms of dementia. In this study, we report normative data on the ACE-R-Italian version, collected on a sample of 264 Italian healthy subjects aging between 60 and 93 years, and with a formal education from 1 to 19 years. The global normal cognition was established in accordance with the Italian version of the Mini–Mental State Examination score and with exclusion criteria derived by a consensus process. Linear regression analysis was performed to evaluate the effect of age, gender, and education on the ACE-R total performance score. We provide correction grids to adjust raw scores and equivalent scores with cut-off value to allow comparison between ACE-R performance and others neuropsychological test scores that can be administered to the same subject.

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Acknowledgments

The authors acknowledge the control subjects and all the physicians at the Santa Maria della Misericordia Hospital in Perugia and the psychologists at the Clinical Psychology and Psychotherapy Adult and Developmental Ages in Taranto for their involvement in this study.

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Authors and Affiliations

  1. Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy

    Martina Pigliautile, Manuela Conestabile della Staffa & Patrizia Mecocci

  2. Department of Neuroscience, Psychology, Drug Research, and Child’s Health (NEUROFARBA)-Section of Psychology, University of Florence, Florence, Italy

    Francesca Chiesi & Caterina Primi

  3. Unit of Clinical Psychology, Azienda Sanitaria Locale, Taranto, Italy

    Sonia Rossetti & Dora Chiloiro

  4. ARC Centre of Excellence in Cognition and its Disorders, Macquarie University, Sydney, Australia

    Monica Ricci

  5. Social and Human Sciences and Education, Department of Philosophy, University of Perugia, Perugia, Italy

    Stefano Federici

Authors
  1. Martina Pigliautile
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  2. Francesca Chiesi
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  3. Sonia Rossetti
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  4. Manuela Conestabile della Staffa
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  5. Monica Ricci
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  6. Stefano Federici
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  7. Dora Chiloiro
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  8. Caterina Primi
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  9. Patrizia Mecocci
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Correspondence to Martina Pigliautile.

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The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Pigliautile, M., Chiesi, F., Rossetti, S. et al. Normative data for the ACE-R in an Italian population sample. Neurol Sci 36, 2185–2190 (2015). https://doi.org/10.1007/s10072-015-2330-y

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  • DOI: https://doi.org/10.1007/s10072-015-2330-y

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