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Influence of age, spatial memory, and ocular fixation on localization of auditory, visual, and bimodal targets by human subjects

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Abstract

A common complaint of the elderly is difficulty identifying and localizing auditory and visual sources, particularly in competing background noise. Spatial errors in the elderly may pose challenges and even threats to self and others during everyday activities, such as localizing sounds in a crowded room or driving in traffic. In this study, we investigated the influence of aging, spatial memory, and ocular fixation on the localization of auditory, visual, and combined auditory–visual (bimodal) targets. Head-restrained young and elderly subjects localized targets in a dark, echo-attenuated room using a manual laser pointer. Localization accuracy and precision (repeatability) were quantified for both ongoing and transient (remembered) targets at response delays up to 10 s. Because eye movements bias auditory spatial perception, localization was assessed under target fixation (eyes free, pointer guided by foveal vision) and central fixation (eyes fixed straight ahead, pointer guided by peripheral vision) conditions. Spatial localization across the frontal field in young adults demonstrated (1) horizontal overshoot and vertical undershoot for ongoing auditory targets under target fixation conditions, but near-ideal horizontal localization with central fixation; (2) accurate and precise localization of ongoing visual targets guided by foveal vision under target fixation that degraded when guided by peripheral vision during central fixation; (3) overestimation in horizontal central space (±10°) of remembered auditory, visual, and bimodal targets with increasing response delay. In comparison with young adults, elderly subjects showed (1) worse precision in most paradigms, especially when localizing with peripheral vision under central fixation; (2) greatly impaired vertical localization of auditory and bimodal targets; (3) increased horizontal overshoot in the central field for remembered visual and bimodal targets across response delays; (4) greater vulnerability to visual bias with bimodal stimuli. Results highlight age-, memory-, and modality-dependent deterioration in the processing of auditory and visual space, as well as an age-related increase in the dominance of vision when localizing bimodal sources.

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References

  • Abel SM, Giguere C, Consoli A, Papsin BC (2000) The effect of aging on horizontal plane sound localization. J Acoust Soc Am 108(2):743–752

    Article  PubMed  CAS  Google Scholar 

  • Amenedo E, Diaz F (1998) Automatic and effortful processes in auditory memory reflected by event-related potentials. Age-related findings. Electroencephalogr Clin Neurophysiol 108(4):361–369

    Article  PubMed  CAS  Google Scholar 

  • Baddeley A (1986) Working memory. Oxford University Press, Oxford

    Google Scholar 

  • Barton EJ, Sparks DL (2001) Saccades to remembered targets exhibit enhanced orbital position effects in monkeys. Vision Res 41(18):2393–2406

    Article  PubMed  CAS  Google Scholar 

  • Bertelson P, de Gelder B (2004) The psychology of multimodal perception. In: Spence C, Driver J (eds) Crossmodal space and crossmodal attenion. Oxford University Press, Oxford, pp 151–177

    Google Scholar 

  • Bruce PR, Herman JF (1986) Adult age differences in spatial memory: effects of distinctiveness and repeated experience. J Gerontol 41(6):774–777

    PubMed  CAS  Google Scholar 

  • Burke MR, Grieve KL (2005) Touch responses made to remembered and visual target locations in the dark: a human psychophysical study. Exp Brain Res 160(4):460–466

    Article  PubMed  CAS  Google Scholar 

  • Carlile S, Leong P, Hyams S (1997) The nature and distribution of errors in sound localization by human listeners. Hear Res 114(1–2):179–196

    Article  PubMed  CAS  Google Scholar 

  • Chao LL, Knight RT (1997) Age-related prefrontal alterations during auditory memory. Neurobiol Aging 18(1):87–95

    Article  PubMed  CAS  Google Scholar 

  • Chieffi S, Allport DA (1997) Independent coding of target distance and direction in visuo-spatial working memory. Psychol Res 60(4):244–250

    Article  PubMed  CAS  Google Scholar 

  • Clark EC, O’Neill WE, Paige GD (2012) Oculomotor adaptation of sound localization depends upon the temporal relationship between targets and eye movements. In: 35th annual meeting of the Association for Research in Otolaryngology Abstr: 657

  • Cooper K, O’Neill WE, Paige GD (2011) Adaptation of sound localization in the direction of eye movement is linearly related to ocular eccentricity. In: Abstracts of the 34th annual meeting of the Association for Research in Otolaryngology

  • Cowey A, Rolls ET (1974) Human cortical magnification factor and its relation to visual acuity. Exp Brain Res 21(5):447–454

    Article  PubMed  CAS  Google Scholar 

  • Cui QN, O’Neill WE, Paige GD (2010a) Advancing age alters the influence of eye position on sound localization. Exp Brain Res 206(4):371–379. doi:10.1007/s00221-010-2413-1

    Article  PubMed  Google Scholar 

  • Cui QN, Razavi B, O’Neill WE, Paige GD (2010b) Perception of auditory, visual, and egocentric spatial alignment adapts differently to changes in eye position. J Neurophysiol 103(2):1020–1035

    Article  PubMed  Google Scholar 

  • Daniel PM, Whitteridge D (1961) The representation of the visual field on the cerebral cortex in monkeys. J Physiol 159:203–221

    PubMed  CAS  Google Scholar 

  • Dobreva MS, O’Neill WE, Paige GD (2009) Influence of age and memory on head-free localization of auditory and visual targets. Neural control of movement Abstr: F-19

  • Dobreva MS, O’Neill WE, Paige GD (2011) Influence of aging on human sound localization. J Neurophysiol 105(5):2471–2486. doi:10.1152/jn.00951.2010

    Article  PubMed  Google Scholar 

  • Fuller JH (1996) Comparison of horizontal head movements evoked by auditory and visual targets. J Vestib Res 6(1):1–13

    Article  PubMed  CAS  Google Scholar 

  • Gnadt JW, Bracewell RM, Andersen RA (1991) Sensorimotor transformation during eye movements to remembered visual targets. Vision Res 31(4):693–715

    Article  PubMed  CAS  Google Scholar 

  • Godfroy M, Roumes C, Dauchy P (2003) Spatial variations of visual-auditory fusion areas. Perception 32(10):1233–1245

    Article  PubMed  Google Scholar 

  • Goldring JE, Dorris MC, Corneil BD, Ballantyne PA, Munoz DP (1996) Combined eye-head gaze shifts to visual and auditory targets in humans. Exp Brain Res 111(1):68–78

    Article  PubMed  CAS  Google Scholar 

  • Golob EJ, Starr A (2000) Age-related qualitative differences in auditory cortical responses during short-term memory. Clin Neurophysiol 111(12):2234–2244

    Article  PubMed  CAS  Google Scholar 

  • Goossens HH, Van Opstal AJ (1997) Human eye-head coordination in two dimensions under different sensorimotor conditions. Exp Brain Res 114(3):542–560

    Article  PubMed  CAS  Google Scholar 

  • Guitton D, Volle M (1987) Gaze control in humans: eye-head coordination during orienting movements to targets within and beyond the oculomotor range. J Neurophysiol 58(3):427–459

    PubMed  CAS  Google Scholar 

  • Hairston WD, Wallace MT, Vaughan JW, Stein BE, Norris JL, Schirillo JA (2003) Visual localization ability influences cross-modal bias. J Cognit Neurosci 15(1):20–29. doi:10.1162/089892903321107792

    Article  CAS  Google Scholar 

  • Hale S, Rose NS, Myerson J, Strube MJ, Sommers M, Tye-Murray N, Spehar B (2011) The structure of working memory abilities across the adult life span. Psychol Aging 26(1):92–110. doi:10.1037/a0021483

    Article  PubMed  Google Scholar 

  • Hay L, Redon C (2006) Response delay and spatial representation in pointing movements. Neurosci Lett 408(3):194–198

    Article  PubMed  CAS  Google Scholar 

  • Henriques DY, Klier EM, Smith MA, Lowy D, Crawford JD (1998) Gaze-centered remapping of remembered visual space in an open-loop pointing task. J Neurosci 18(4):1583–1594

    PubMed  CAS  Google Scholar 

  • ISO (2000) Acoustics: statistical distribution of hearing thresholds as a function of age. ISO 7029. International Organization for Standardization, Geneva, Switzerland

  • Kessels RP, Meulenbroek O, Fernandez G, Olde Rikkert MG (2010) Spatial working memory in aging and mild cognitive impairment: effects of task load and contextual cueing. Neuropsychology, development, and cognition Section B, Aging, neuropsychology and cognition 17(5):556–574. doi:10.1080/13825585.2010.481354

    Article  PubMed  Google Scholar 

  • Leo F, Bolognini N, Passamonti C, Stein BE, Ladavas E (2008) Cross-modal localization in hemianopia: new insights on multisensory integration. Brain J Neurol 131(Pt 3):855–865. doi:10.1093/brain/awn003

    Article  Google Scholar 

  • Lewald J, Ehrenstein WH (2001) Spatial coordinates of human auditory working memory. Brain Res Cogn Brain Res 12(1):153–159

    Article  PubMed  CAS  Google Scholar 

  • Lewald J, Guski R (2003) Cross-modal perceptual integration of spatially and temporally disparate auditory and visual stimuli. Brain Res Cogn Brain Res 16(3):468–478

    Article  PubMed  Google Scholar 

  • Lewald J, Ehrenstein WH, Guski R (2001) Spatio-temporal constraints for auditory–visual integration. Behav Brain Res 121(1–2):69–79

    Article  PubMed  CAS  Google Scholar 

  • Makous JC, Middlebrooks JC (1990) Two-dimensional sound localization by human listeners. J Acoust Soc Am 87(5):2188–2200

    Article  PubMed  CAS  Google Scholar 

  • McEvoy LK, Pellouchoud E, Smith ME, Gevins A (2001) Neurophysiological signals of working memory in normal aging. Brain Res Cogn Brain Res 11(3):363–376

    Article  PubMed  CAS  Google Scholar 

  • McIntyre J, Stratta F, Lacquaniti F (1997) Viewer-centered frame of reference for pointing to memorized targets in three-dimensional space. J Neurophysiol 78(3):1601–1618 (erratum appears in J Neurophysiol 1998 Jun; 79(6):3301)

    PubMed  CAS  Google Scholar 

  • McIntyre J, Stratta F, Lacquaniti F (1998) Short-term memory for reaching to visual targets: psychophysical evidence for body-centered reference frames. J Neurosci 18(20):8423–8435

    PubMed  CAS  Google Scholar 

  • Middlebrooks JC (1992) Narrow-band sound localization related to external ear acoustics. J Acoust Soc Am 92(5):2607–2624

    Article  PubMed  CAS  Google Scholar 

  • Moffat SD, Zonderman AB, Resnick SM (2001) Age differences in spatial memory in a virtual environment navigation task. Neurobiol Aging 22(5):787–796

    Article  PubMed  CAS  Google Scholar 

  • Muller NG, Knight RT (2002) Age-related changes in fronto-parietal networks during spatial memory: an ERP study. Brain Res Cogn Brain Res 13(2):221–234

    Article  PubMed  CAS  Google Scholar 

  • Myers RH (2000) The multiple linear regression model. In: Classical and modern regression with applications. Brooks/Cole, pp 135–153

  • Neils J, Newman CW, Hill M, Weiler E (1991) The effects of rate, sequencing, and memory on auditory processing in the elderly. J Gerontol 46(2):P71–P75

    PubMed  CAS  Google Scholar 

  • Noble W, Byrne D, Lepage B (1994) Effects on sound localization of configuration and type of hearing impairment. J Acoust Soc Am 95(2):992–1005

    Article  PubMed  CAS  Google Scholar 

  • Opris I, Barborica A, Ferrera VP (2003) Comparison of performance on memory-guided saccade and delayed spatial match-to-sample tasks in monkeys. Vision Res 43(3):321–332

    Article  PubMed  Google Scholar 

  • Owsley C, Burton-Danner K, Jackson GR (2000) Aging and spatial localization during feature search. Gerontology 46(6):300–305

    Article  PubMed  CAS  Google Scholar 

  • Ploner CJ, Gaymard B, Rivaud S, Agid Y, Pierrot-Deseilligny C (1998) Temporal limits of spatial working memory in humans. Eur J Neurosci 10(2):794–797

    Article  PubMed  CAS  Google Scholar 

  • Populin LC (2008) Human sound localization: measurements in untrained, head-unrestrained subjects using gaze as a pointer. Exp Brain Res 190(1):11–30

    Article  PubMed  Google Scholar 

  • Proudlock FA, Shekhar H, Gottlob I (2004) Age-related changes in head and eye coordination. Neurobiol Aging 25(10):1377–1385

    Article  PubMed  Google Scholar 

  • Rakerd B, Vander Velde TJ, Hartmann WM (1998) Sound localization in the median sagittal plane by listeners with presbyacusis. J Am Acad Audiol 9(6):466–479

    PubMed  CAS  Google Scholar 

  • Razavi B, O’Neill WE, Paige GD (2005) Both interaural and spectral cues impact sound localization in azimuth. In: Proceedings of the 2nd international IEEE EMBS conference of neural engineering, Arlington, VA, 16–19 March 2005, pp 587–590. doi:10.1109/CNE.2005.1419531

  • Razavi B, O’Neill WE, Paige GD (2007) Auditory spatial perception dynamically realigns with changing eye position. J Neurosci 27(38):10249–10258

    Article  PubMed  CAS  Google Scholar 

  • Razavi B, O’Neill, WE, Paige, GD (2009) Auditory and visual spatial localization using gaze pointing under different sensori-motor contexts. Neural control of movement Abstr: F-20

  • Recanzone GH, Makhamra SD, Guard DC (1998) Comparison of relative and absolute sound localization ability in humans. J Acoust Soc Am 103(2):1085–1097

    Article  PubMed  CAS  Google Scholar 

  • Reuter-Lorenz PA, Jonides J, Smith EE, Hartley A, Miller A, Marshuetz C, Koeppe RA (2000) Age differences in the frontal lateralization of verbal and spatial working memory revealed by PET. J Cognit Neurosci 12(1):174–187

    Article  CAS  Google Scholar 

  • Sekuler R, Ball K (1986) Visual localization: age and practice. J Opt Soc Am [A] 3(6):864–867

    Article  CAS  Google Scholar 

  • Sheth BR, Shimojo S (2001) Compression of space in visual memory. Vision Res 41(3):329–341

    Article  PubMed  CAS  Google Scholar 

  • Siegmund H, Stoppa M, Santibanez G (1987) Eye and head movements to visual and auditory targets. Act Nerv Super (Praha) 29(2):73–82

    CAS  Google Scholar 

  • Smith EE, Jonides J (1997) Working memory: a view from neuroimaging. Cognit Psychol 33(1):5–42. doi:10.1006/cogp.1997.0658

    Article  PubMed  CAS  Google Scholar 

  • Sweeney JA, Rosano C, Berman RA, Luna B (2001) Inhibitory control of attention declines more than working memory during normal aging. Neurobiol Aging 22(1):39–47

    Article  PubMed  CAS  Google Scholar 

  • Vliegen J, Van Grootel TJ, Van Opstal AJ (2004) Dynamic sound localization during rapid eye-head gaze shifts. J Neurosci 24(42):9291–9302 (erratum appears in J Neurosci. 2004 Nov 3; 24(44): following 10034)

    Article  PubMed  CAS  Google Scholar 

  • von Noorden GK (1985) Visual acuity and aniseikonia. In: Binocular vision and ocular motility: theory and management of strabismus, 3rd edn. The C.V. Mosby Company, St. Louis, pp 124–134

  • White JM, Sparks DL, Stanford TR (1994) Saccades to remembered target locations: an analysis of systematic and variable errors. Vision Res 34(1):79–92

    Article  PubMed  CAS  Google Scholar 

  • Whittington DA, Hepp-Reymond MC, Flood W (1981) Eye and head movements to auditory targets. Exp Brain Res 41(3–4):358–363

    PubMed  CAS  Google Scholar 

  • Zambarbieri D, Schmid R, Versino M, Beltrami G (1997) Eye-head coordination toward auditory and visual targets in humans. J Vestib Res 7(2–3):251–263

    Article  PubMed  CAS  Google Scholar 

  • Zwiers MP, Van Opstal AJ, Paige GD (2003) Plasticity in human sound localization induced by compressed spatial vision. Nat Neurosci 6(2):175–181. doi:10.1038/nn999

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Neurobiology and Anatomy, School of Medicine and Dentistry, University of Rochester, Box 603, Rochester, NY, 14642-8603, USA

    Marina S. Dobreva, William E. O’Neill & Gary D. Paige

  2. Center for Navigation and Communication Sciences, School of Medicine and Dentistry, University of Rochester, Rochester, NY, 14642-8603, USA

    William E. O’Neill & Gary D. Paige

  3. Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY, 14627, USA

    William E. O’Neill

  4. Center for Visual Science, College of Arts, Sciences, and Biomedical Engineering, University of Rochester, Rochester, NY, 14627, USA

    Gary D. Paige

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  1. Marina S. Dobreva
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  2. William E. O’Neill
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  3. Gary D. Paige
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Correspondence to Gary D. Paige.

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Dobreva, M.S., O’Neill, W.E. & Paige, G.D. Influence of age, spatial memory, and ocular fixation on localization of auditory, visual, and bimodal targets by human subjects. Exp Brain Res 223, 441–455 (2012). https://doi.org/10.1007/s00221-012-3270-x

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  • DOI: https://doi.org/10.1007/s00221-012-3270-x

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