Considerations on Temperature, Longevity and Aging

Abstract.

A modest reduction in body temperature prolongs longevity and may retard aging in both poikilotherm and homeotherm animals. Some of the possible mechanisms mediating these effects are considered here with respect to major aging models and theories.

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1. Molecular and Integrative Neurosciences Department, The Harold Dorris Neurological Research Institute, The Scripps Research Institute, 10550 North Torrey Pines Road, mail SR307, La Jolla, California, 92037, USA

   B. Conti

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1. B. Conti
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Correspondence to B. Conti.

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Received 21 November 2007; received after revision 25 March 2008; accepted 01 April 2008

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Conti, B. Considerations on Temperature, Longevity and Aging. Cell. Mol. Life Sci. 65, 1626–1630 (2008). https://doi.org/10.1007/s00018-008-7536-1

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• Published: 21 April 2008

• Issue Date: June 2008

• DOI: https://doi.org/10.1007/s00018-008-7536-1

Keywords.

• Temperature
• aging
• longevity
• calorie restriction
• energy