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The size of the community rather than its geographical location better defines the risk of iodine deficiency: Results of an extensive survey in Southern Italy

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Abstract

Aim: The objective of this study was to establish the status of iodine nutrition in Southern Italy. Material and methods: The survey was carried out on 11–14 yr old children attending primary school and living in urban and non urban areas of 8 regions of Southern Italy. Urinary iodine excretion (UIE) was measured in 23,103 urinary samples randomly collected. Results: Median UIE in the whole studied population was 74 µg/l [interquartile range (IR) 34–139 µg/l]. UIE was significantly higher in chief towns compared to non chief towns (81 µg/l, IR 39–145 µg/l vs 73 µg/l, IR 33–138 µg/l, p<0.0001) and in areas with >500 inhabitants per km2 (median 87 µg/l, IR 43–154 µg/l) compared to areas with 100–500 per km2 (median 66 µg/l, IR 29–126 µg/l, p<0.0001) and with <100 per km2 (median 61 µg/l, IR 25–121 µg/l, p<0.0001). Median UIE was significantly lower in inland mountainous/hilly areas (68 µg/l, IR 30–129 µg/l) compared to coastal mountainous/hilly areas (79 µg/l, IR 37–144 µg/l, p<0.0001) and lowland (79 µg/l, IR 37–146 µg/l, p<0.0001). According to a binary logistic regression model, population density was the only independent parameter significantly associated with UIE≥100 µg/l. Conclusion: The results of the present survey indicate that: 1) in Southern Italy mild to moderate iodine deficiency is still present; 2) median UIE in non urban areas is lower than in urban areas and is related to the size of the community rather than to its geographical location, being higher in a larger community. This may be due to better diversification of dietary habits and the easier availability of iodized salt and processed food through commercial facilities, more common in larger communities. Future monitoring surveys should take into account these observations.

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Authors and Affiliations

  1. Endocrinology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

    F. Aghini-Lombardi MD, P. Vitti, L. Antonangeli, E. Fiore & A. Pinchera

  2. Department of Electrical System and Automation, University of Pisa, Pisa, Italy

    P. Piaggi

  3. National Research Council, Rome, Italy

    A. Pallara

  4. Department of Biology and Cellular and Molecular Pathology, University of Naples, Naples, Italy

    E. Consiglio

Authors
  1. F. Aghini-Lombardi MD
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  2. P. Vitti
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  3. L. Antonangeli
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  4. E. Fiore
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  5. P. Piaggi
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  6. A. Pallara
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  7. E. Consiglio
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  8. A. Pinchera
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Consortia

the Southern Italy Study Group for Iodine Deficiency Disorders

Corresponding author

Correspondence to F. Aghini-Lombardi MD.

Additional information

For the list of members see Appendix.

Deceased October 10, 2012.

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Aghini-Lombardi, F., Vitti, P., Antonangeli, L. et al. The size of the community rather than its geographical location better defines the risk of iodine deficiency: Results of an extensive survey in Southern Italy. J Endocrinol Invest 36, 282–286 (2013). https://doi.org/10.1007/BF03347103

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  • DOI: https://doi.org/10.1007/BF03347103

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