A computer based model for realistic simulations of neural networks

• Anderson JA, Rosenfeld E (1988) Neurocomputing. Foundations of research. MIT Press, Cambridge, Mass

  Google Scholar 

• Ascher P, Nowak L (1988) The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. J Physiol 399:247–266

  Google Scholar 

• Baldissera F, Gustafsson B (1974) Firing behaviour of a neurone model based on the afterhyperpolarization conductance time course and algebraical summation. Adaptation and steady state firing. Acta Physiol Scand 92:27–47

  Google Scholar 

• Blaustein MP (1988) Calcium transport and buffering in neurons. Trends Neurosci 11:438–443

  Google Scholar 

• Brodin L, Tråvén H, Lansner A, Wallén P, Ekeberg Ö, Grillner S (1991) Computer simulation of N-methyl-D-aspartate (NMDA) receptor induced membrane properties in a neuron model. J Neurophysiol (in press)

• Buchanan JT, Grillner S (1987) Newly identified ‘glutamate interneurons’ and their role in locomotion in the lamprey spinal cord. Science 236:312–314

  Google Scholar 

• Connors WB, Gutnick MJ (1990) Intrinsic firing patterns of diverse neocortical neurons. Trends Neurosci 13:99–104

  Google Scholar 

• Dahlquist G, Björck Å (1974) Numerical methods. Prentice Hall, Englewood Cliffs NJ

  Google Scholar 

• Dale N, Grillner S (1986) Dual-component synaptic potentials in the lamprey mediated by excitatory amino acid receptors. J Neurosci 6:2653–2661

  Google Scholar 

• Edman Å, Gestrelius S, Grampp W (1987a) Analysis of gated membrane currents and mechanisms of firing control in the rapidly adapting lobster stretch receptor neurone. J Physiol 385:649–669

  Google Scholar 

• Edman Å, Gestrelius S, Grampp W (1987b) Current activation by membrane hyperpolarization in the slowly adapting lobster stretch receptor neurone. J Physiol 385:671–690

  Google Scholar 

• Ekeberg Ö, Stensmo M, Lansner A (1990) SWIM a simulator for real neural networks. Tech Rep TRITA-NA-9014, Royal Institute of Technology, Stockholm

  Google Scholar 

• Frankenhaeuser B, Huxley AF (1964) The action potential in the myelinated nerve fibre of Xenopus Laevis as computed on the basis of voltage clamp data. J Physiol 171:302–315

  Google Scholar 

• Fransén E, Lansner A (1990) Modelling Hebbian cell assemblies comprised of cortical neurons. Proc Open Network Conference on Neural Mechanisms of Learning and Memory, London 3–6 April 1990, p 4:9

• Getting PA (1989) Emerging principles governing the operation of neural networks. Ann Rev Neurosci 12:185–204

  Google Scholar 

• Grillner S, Wallén P, Dale N, Brodin L, Buchanan JT, Hill R (1987) Transmitters, membrane properties and network circuitry in the control of locomotion in lamprey. Trends Neurosci 10:34–41

  Google Scholar 

• Grillner S, Buchanan JT, Lansner A (1988) Simulations of the segmental burst generating network for locomotion in lamprey. Neurosci Lett 89:31–35

  Google Scholar 

• Grillner S, Christenson J, Brodin L, Wallén P, Hill R, Lansner A, Ekeberg Ö (1989) Locomotor system in lamprey: neural mechanisms controlling spinal rhythm generation. In: Jacklet JW (ed) Neural and cellular oscillators, Dekker, New York, pp 407–434

  Google Scholar 

• Grillner S, Wallén P, Brodin L, Lansner A (1991) Neuronal network generating locomotor behavior in lamprey: circuitry, transmitters, membrane properties and simulations. Ann Rev Neurosci 14:169–199

  Google Scholar 

• Hill RH, Åhrem P, Grillner S (1985) Ionic mechanisms of 3 types of functionally different neurons in the lamprey spinal cord. Brain Res 358:40–52

  Google Scholar 

• Hill RH, Brodin L, Grillner S (1989) Activation of N-methyl-D-aspartate (NMDA) receptors augments repolarizing responses in lamprey spinal neurons. Brain Res 499:388–392

  Google Scholar 

• Hille B (1984) Ionic channels of excitable membranes. Sinauer, Sunderland, Mass

  Google Scholar 

• Hodgkin AL, Huxley AF (1952) A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 117:500–544

  Google Scholar 

• Holden AV (1980) Autorhythmicity and entrainment in excitable membranes. Biol Cybern 38:1–8

  Google Scholar 

• Kernell D, Sjöholm H (1972) Motoneurone models based on ‘voltage clamp equations’ for peripheral nerve. Acta Physiol Scand 86:546–562

  Google Scholar 

• Kernell D, Sjöholm H (1973) Repetitive impulse firing: comparisons between neurone models based on ‘voltage clamp equations’ and spinal motoneurones. Acta Physiol Scand 87:40–56

  Google Scholar 

• Koch C, Segev I (1989) Methods in neuronal modeling, from synapses to networks. MIT Press, Cambridge, Mass

  Google Scholar 

• Lansner A (1982) Information processing in a network of model neurons. A computer simulation study. Tech Rep. TRITA-NA8211, Dept. of Numerical Analysis and Computing Science, The Royal Institute of Technology, Stockholm

• Lansner A, Ekeberg Ö (1985) Reliability and speed of recall in an associative network. IEEE Trans PAMI 7:490–498

  Google Scholar 

• Lansner A, Ekeberg Ö (1989) A one-layer feedback artificial neural network with a Bayesian learning rule. Int J Neural Sys 1:77–87

  Google Scholar 

• Lansner A, Ekeberg Ö, Tråvén H, Brodin L, Wallén P, Stensmo M, Grillner S (1989) Simulation of the experimentally established segmental, supraspinal and sensory circuitry underlying locomotion in lamprey. Soc Neurosci (abstr) 15:1049

  Google Scholar 

• Lippmann RP (1987) An introduction to computing with neural nets. IEEE ASSP Mag April:4-22

• MacGregor RJ (1987) Neural and brain modeling. Academic Press, New York

  Google Scholar 

• MacGregor RJ, Lewis ER (1977) Neural modeling. Electrical signal processing in the nervous system. Plenum Press, New York

  Google Scholar 

• MacGregor RJ, Oliver RM (1974) A model for repetitive firing in neurons. Kybernetik 16:53–64

  Google Scholar 

• Mayer ML, MacDermott AB, Westbrook GL, Smith SJ, Barker JL (1987) Agonistand voltage gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III. J Neurosci 7:3230–3244

  Google Scholar 

• Mulloney B, Perkel DH (1988) In: Cohen AH, Grillner S, Rossignol S (eds) Neural control of rhythmic movements in vertebrates. Wiley, pp 415–453

• Neher E, Steinbach JH (1978) Local anaesthetics transiently block currents through single acetylcholine-receptor channels. J Physiol 277:153–176

  Google Scholar 

• Perkel DH (1976) A computer program for simulating a network of interacting neurons. Comput Biomed Res 9:31–74

  Google Scholar 

• Rall W (1977) Core conductor theory and cable properties of neurons. In: Brookhart JM, Mountcastle VB, Kandel ER (eds) Handbook of physiology, Sect. 1, vol 1(1). Am Physiol Soc 39–97

• Roberts A, Tunstall MJ (1990) Mutual re-excitation with post-inhibitory rebound: a simulation study on the mechanisms for locomotor rhythm generation in the spinal cord of Xenopus embryos. Eur J Neurosci 2:11–23

  Google Scholar 

• Rumelhart DE, McClelland JL (1986) Parallel distributed processing. Explorations in the microstructures of cognition. MIT Press, Cambridge Mass

  Google Scholar 

• Stein RB (1965) A theoretical analysis of neuronal variability. Biophys J 5:173–194

  Google Scholar 

• Traub RD, Llinas R (1977) The spatial distribution of ionic conductances in normal and axotomized motorneurons. J. Neurosci 2:829–849

  Google Scholar 

• Tsien RW (1983) Calcium channels in excitable cell membranes. Ann Rev Physiol 45:341–358

  Google Scholar 

• Tsien RW, Lipscombe D, Madison DV, Bley KR, Fox AP (1988) Multiple types of neuronal calcium channels and their selective modulation. Trends Neurosci 11:431–438

  Google Scholar 

• Wallén P, Grillner S (1987) N-methyl-D-aspartate receptor-induced, inherent oscillatory activity in neurons active during fictive locomotion in the lamprey. J Neurosci 7:2745–2755

  Google Scholar 

• Wallöe L (1968) Transfer of signals through a second order sensory neuron. Universitesforlagets Trykningssentral, Oslo

  Google Scholar 

• Watkins JC, Evans RH (1981) Excitatory amino acid transmitters. Ann Rev Pharmacol Toxicol 21:165–205

  Google Scholar 

Download references