Abstract
Data augmentation methods have proven effective in addressing the scarcity of training data. However, two unsolved challenges still limit their potential in medical image segmentation. Specifically, (1) existing data augmentation methods cannot establish the interaction between two tasks. They treat data augmentation and segmentation as two independent tasks, which ignores the inter-correlation. (2) They cannot enhance the weak boundary of utmost significance in medical image segmentation. Instead, they focus exclusively on increasing the number and diversity of training samples. We propose a novel and generalized contrast-adjustment guided growth method (CaGM) with two innovations to solve the above challenges. Specifically, (1) for the first time, the concept of growth method is proposed, which innovatively unifies the segmentation and augmentation into one framework, and establishes the inter-correlation between two tasks for boosting the segmentation. (2) A novel contrast-adjustment method is proposed, which enables boosting the contrast of boundaries and tackling the challenge of weak boundaries. Experimental results on two datasets and four baseline segmentation methods demonstrate that the CaGM has exhibited remarkable generality. The CaGM significantly improves segmentation performance and outperforms state-of-the-art data augmentation methods.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Wang, J., et al.: SDPN: a slight dual-path network with local-global attention guided for medical image segmentation. IEEE J. Biomed. Health Inform. 27, 2956–2967 (2023)
Yuan, L., Liu, X., Yu, J., Li, Y.: A full-set tooth segmentation model based on improved pointnet++. Vis. Intell. 1(1) (2023)
Liu, C., Jiang, X., Ding, H.: Primitivenet: decomposing the global constraints for referring segmentation. Vis. Intell. 2 (2024)
Zhu, Q., Du, B., Yan, P.: Boundary-weighted domain adaptive neural network for prostate MR image segmentation. IEEE Trans. Med. Imaging 39(3), 753–763 (2019)
Herzog, L., Murina, E., Dürr, O., Wegener, S., Sick, B.: Integrating uncertainty in deep neural networks for MRI based stroke analysis. Medical Image Anal. 65, 101790 (2020)
Kofler, A., Dewey, M., Schaeffter, T., Wald, C., Kolbitsch, C.: Spatio-temporal deep learning-based undersampling artefact reduction for 2D radial cine MRI with limited training data. IEEE Trans. Medical Imaging 39(3), 703–717 (2020)
LaLonde, R., Xu, Z., Irmakci, I., Jain, S., Bagci, U.: Capsules for biomedical image segmentation. Medical Image Anal. 68, 101889 (2021)
Tam, C.M., Zhang, D., Chen, B., Peters, T.M., Li, S.: Holistic multitask regression network for multiapplication shape regression segmentation. Med. Image Anal. 65, 101783 (2020)
Zhang, H., Cissé, M., Dauphin, Y.N., Lopez-Paz, D.: mixup: Beyond empirical risk minimization. In: Proceedings of International Conference on Learning Representations (2018)
Yun, S., Han, D., Chun, S., Oh, S.J., Yoo, Y., Choe, J.: Cutmix: regularization strategy to train strong classifiers with localizable features. In: Proceedings of IEEE International Conference on Computer Vision, pp. 6022–6031 (2019)
Zhang, X., Liu, C., Ou, N., Zeng, X., Xiong, X., Yu, Y., Liu, Z., Ye, C.: CarveMix: a simple data augmentation method for brain lesion segmentation. In: Proceedings of International Conference on Medical Image Computing and Computer Assisted Intervention, vol. 13434, pp. 683–692 (2022)
Zhu, Q., Wang, Y., Yin, L., Yang, J., Liao, F., Li, S.: Selfmix: a self-adaptive data augmentation method for lesion segmentation. In: Proceedings of International Conference on Medical Image Computing and Computer Assisted Intervention, vol. 13434, pp. 683–692 (2022)
Hamghalam, M., Wang, T., Lei, B.: High tissue contrast image synthesis via multistage attention-GAN: application to segmenting brain MR scans. Neural Netw. 132, 43–52 (2020)
Gilbert, A., et al.: Generating synthetic labeled data from existing anatomical models: an example with echocardiography segmentation. IEEE Trans. Medical Imaging 40(10), 2783–2794 (2021)
Yu, Z., Han, X., Zhang, S., Feng, J., Peng, T., Zhang, X.-Y.: Mousegan++: unsupervised disentanglement and contrastive representation for multiple MRI modalities synthesis and structural segmentation of mouse brain. IEEE Trans. Med. Imaging 42(4), 1197–1209 (2023)
Fan, C.-C., et al.: TR-GAN: multi-session future MRI prediction with temporal recurrent generative adversarial network. IEEE Trans. Med. Imaging 41(8), 1925–1937 (2022)
Zhu, Q., Du, B., Yan, P.: Self-supervised training of graph convolutional networks. arXiv:2006.02380 (2020)
Zhou, Z., Sodha, V., Pang, J., Gotway, M.B., Liang, J.: Models genesis. Med. Image Anal. 67, 101840 (2021)
Chen, X., Zhang, Y., Wang, Y.: MTP: multi-task pruning for efficient semantic segmentation networks. In: IEEE International Conference on Multimedia and Expo (ICME), pp. 1–6 (2022)
Li, X., Yu, L., Chen, H., Fu, C., Heng, P.: Semi-supervised skin lesion segmentation via transformation consistent self-ensembling model. In: British Machine Vision Conference. BMVA Press, p. 63 (2018)
Su, Y., Liu, Q., Xie, W., Hu, P.: YOLO-LOGO: a transformer-based YOLO segmentation model for breast mass detection and segmentation in digital mammograms. Comput. Methods Programs Biomed. 221, 106903 (2022)
Li, X., Yu, L., Chen, H., Fu, C.-W., Xing, L., Heng, P.-A.: Transformation-consistent self-ensembling model for semisupervised medical image segmentation. IEEE Trans. Neural Netw. Learn. Syst. 32(2), 523–534 (2021)
Pereira, S., Pinto, A., Alves, V., Silva, C.A.: Brain tumor segmentation using convolutional neural networks in MRI images. IEEE Trans. Med. Imaging 35(5), 1240–1251 (2016)
González Sánchez, J.C., Magnusson, M., Sandborg, M., Tedgren, Å.C., Malusek, A.: Segmentation of bones in medical dual-energy computed tomography volumes using the 3D U-Net. Phys. Med. 69, 241–247 (2020)
Chen, C., Hammernik, K., Ouyang, C., Qin, C., Bai, W., Rueckert, D.: Cooperative training and latent space data augmentation for robust medical image segmentation. In: Proceedings of International Conference on Medical Image Computing and Computer Assisted Intervention, vol. 12903, pp. 149–159 (2021)
Cai, J.: Segmentation and diagnosis of liver carcinoma based on adaptive scale-kernel fuzzy clustering model for CT images. J. Med. Syst. 43(11), 322:1–322:11 (2019)
Zhong, Z., Zheng, L., Kang, G., Li, S., Yang, Y.: Random erasing data augmentation. In: Proceedings of the AAAI Conference on Artificial Intelligence, pp. 13,001–13,008 . AAAI Press (2020)
Wang, X., Wan, S., Jin, P.: Few-shot learning with random erasing and task-relevant feature transforming. In: International Conference on Artificial Neural Networks, vol. 12892, pp. 512–524. Springer (2021)
Su, S., Wang, H., Yang, M.: Suppressing style-sensitive features via randomly erasing for domain generalizable semantic segmentation. In: Proceedings of Chinese Conference on Pattern Recognition and Computer Vision, vol. 13022, pp. 300–311. Springer (2021)
Jamaludin, A., Kadir, T., Zisserman, A.: Spinenet: automated classification and evidence visualization in spinal MRIs. Med. Image Anal. 41, 63–73 (2017)
Karani, N., Erdil, E., Chaitanya, K., Konukoglu, E.: Test-time adaptable neural networks for robust medical image segmentation. Med. Image Anal. 68, 101907 (2021)
Reza, A.M.: Realization of the contrast limited adaptive histogram equalization (CLAHE) for real-time image enhancement. J. VLSI Signal Process. 38(1), 35–44 (2004)
Menze, B.H., Jakab, A., Bauer, S., Kalpathy-Cramer, J., Farahani, K., Kirby, J.S.: The multimodal brain tumor image segmentation benchmark (BRATS). IEEE Trans. Med. Imaging 34(10), 1993–2024 (2015)
Kingma, D.P., Ba, J.: Adam: a method for stochastic optimization. In: Proceedings of International Conference on Learning Representations (2015)
Ronneberger, O., Fischer, P., Brox, T.: U-Net: convolutional networks for biomedical image segmentation. In: Proceedings of International Conference on Medical Image Computing and Computer Assisted Intervention, pp. 234–241 (2015)
Milletari, F., Navab, N., Ahmadi, S.: V-Net: fully convolutional neural networks for volumetric medical image segmentation. In: Fourth International Conference on 3D Vision, pp. 565–571 (2016)
Oktay, O., Schlemper, J., Folgoc, L.L., Lee, M.C.H., Heinrich, M.P., Misawa, K.: Attention U-Net: learning where to look for the pancreas. CoRR. arXiv:1804.03999 (2018)
Isensee, F., Jaeger, P.F., Kohl, S.A.A., Petersen, J., Maier-Hein, K.H.: nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat. Methods 18, 203–211 (2021)
Xu, W., Yang, H., Zhang, M., Pan, X., Liu, W., Yan, S.: Retinal vessel segmentation with VAE reconstruction and multi-scale context extractor. In: 19th IEEE International Symposium on Biomedical Imaging, pp. 1–5 (2022)
Acknowledgments
This work was supported by the National Key Research and Development Program of China 2023YFC2705700, National Natural Science Foundation of China under Grants (62225113, 62222112 and 62176186), the Innovative Research Group Project of Hubei Province under Grants 2024AFA017.
Author information
Authors and Affiliations
Corresponding authors
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2025 The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
About this paper
Cite this paper
Tang, Q., Zhu, Q., Xu, Y., Du, B. (2025). A Generalized Contrast-Adjustment Guided Growth Method for Medical Image Segmentation. In: Lin, Z., et al. Pattern Recognition and Computer Vision. PRCV 2024. Lecture Notes in Computer Science, vol 15045. Springer, Singapore. https://doi.org/10.1007/978-981-97-8499-8_7
Download citation
DOI: https://doi.org/10.1007/978-981-97-8499-8_7
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-97-8498-1
Online ISBN: 978-981-97-8499-8
eBook Packages: Computer ScienceComputer Science (R0)