Abstract
This work encompasses together a number of diverse disciplines (physiology, biomechanics, fluid mechanics and simulation) in order to develop a predictive model of the behaviour of a prosthetic heart valve in vivo. The application of simulation, for the study of other cardiovascular problems, such as blood clotting is also discussed. A commercial, finite volume, computational fluid dynamics (CFD) code (ANSYS/CFX) is used for the 3D component of the model. This software provides technical options for advanced users which allow user-specific variables to be defined that will interact with the flow solver. User-defined functions and junction boxes offer appropriate options to facilitate multi-physics and multi-scale complex applications. Our main goal is to present a 3D model using the internal features available in ANSYS/CFX coupled to a multiscale model of the left ventricle to address complex cardiovascular problems.
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Díaz-Zuccarini, V., Rafirou, D., Hose, D.R., Lawford, P.V., Narracott, A.J. (2007). Multi-physics and Multi-scale Modelling in Cardiovascular Physiology: Advanced User Methods for Simulation of Biological Systems with ANSYS/CFX. In: Shi, Y., van Albada, G.D., Dongarra, J., Sloot, P.M.A. (eds) Computational Science – ICCS 2007. ICCS 2007. Lecture Notes in Computer Science, vol 4487. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-72584-8_105
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DOI: https://doi.org/10.1007/978-3-540-72584-8_105
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-72583-1
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