Abstract
The phylogenetic relationships among the members of species complexes can be inferred from the distribution of fixed inversions if outgroup arrangements are known. The Anopheles gambiae complex consists of seven African mosquito species that can be differentiated based on ten fixed inversions. However, the phylogenetic relationships among the members remain unclear. This paper demonstrates that physical maps of the outgroup speciesA. funestus and A. stephensi can be used for determining ancestral chromosome arrangements in the A. gambiae complex. Gene order comparisons have been performed using the Multiple Genome Rearrangements (MGR) and Sorting Permutation by Reversals and block-INterchanGes (SPRING) programs. The analysis has identified the chromosomal arrangements which are likely to be the ancestral in the complex.
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Coluzzi, M., Sabatini, A., della Torre, A., Di Deco, M.A., Petrarca, V.: A polytene chromosome analysis of the Anopheles gambiae species complex. Science 298, 1415–1418 (2002)
Sharakhov, I.V., White, B.J., Sharakhova, M.V., Kayondo, J., Lobo, N.F., Santolamazza, F., Della Torre, A., Simard, F., Collins, F.H., Besansky, N.J.: Breakpoint structure reveals the unique origin of an interspecific chromosomal inversion (2La) in the Anopheles gambiae complex. Proc. Natl. Acad. Sci. U S A 103, 6258–6262 (2006)
Coluzzi, M., Sabatini, A., Petrarca, V., Di Deco, M.A.: Chromosomal differentiation and adaptation to human environments in the Anopheles gambiae complex. Trans. R Soc. Trop. Med. Hyg. 73, 483–497 (1979)
Ayala, F.J., Coluzzi, M.: Chromosome speciation: humans, Drosophila, and mosquitoes. Proc. Natl. Acad. Sci. USA 1, 6535–6542 (2005)
Pape, T.: Cladistic analyses of mosquito chromosome data in Anopheles subgenus Cellia (Diptera: Culicidae). In: Mosq. Syst., pp. 241–211 (1992)
Sharakhov, I.V., Serazin, A.C., Grushko, O.G., Dana, A., Lobo, N., Hillenmeyer, M.E., Westerman, R., Romero-Severson, J., Costantini, C., Sagnon, N., Collins, F.H., Besansky, N.J.: Inversions and gene order shuffling in Anopheles gambiae and A funestus. Science 298, 182–185 (2002)
Sharakhov, I., Braginets, O., Grushko, O., Cohuet, A., Guelbeogo, W.M., Boccolini, D., Weill, M., Costantini, C., Sagnon, N., Fontenille, D., Yan, G., Besansky, N.J.: A microsatellite map of the African human malaria vector Anopheles funestus. J. Hered 95, 29–34 (2004)
Green, C., Hunt, R.: Interpretation of variation in ovarian polytene chromosomes of Anopheles funestus Giles, A. parensis Gillies, and A. aruni? Genetica 51, 187–195 (1980)
Krzywinski, J., Grushko, O.G., Besansky, N.J.: Analysis of the complete mitochondrial DNA from Anopheles funestus: an improved dipteran mitochondrial genome annotation and a temporal dimension of mosquito evolution. Mol. Phylogenet Evol. 39, 417–423 (2006)
Harbach, R.E., Kitching, I.J.: Reconsideration of anopheline mosquito phylogeny (Diptera: Culicidae: Anophelinae) based on morphological data. Systematics and Biodiversity 3, 345–374 (2005)
Marshall, J.C., Powell, J.R., Caccone, A.: Short report: Phylogenetic relationships of the anthropophilic Plasmodium falciparum malaria vectors in Africa. Am. J. Trop. Med. Hyg. 73, 749–752 (2005)
Bourque, G., Pevzner, P.A.: Genome-scale evolution: reconstructing gene orders in the ancestral species. Genome Res. 12, 26–36 (2002)
Lin, Y.C., Lu, C.L., Liu, Y.C., Tang, C.Y.: SPRING: a tool for the analysis of genome rearrangement using reversals and block-interchanges. Nucleic Acids Res. 34, W696–699 (2006)
Lim, J., Gowda, D.C., Krishnegowda, G., Luckhart, S.: Induction of nitric oxide synthase in Anopheles stephensi by Plasmodium falciparum: mechanism of signaling and the role of parasite glycosylphosphatidylinositols. Infect. Immun. 73, 2778–2789 (2005)
Luckhart, S., Rosenberg, R.: Gene structure and polymorphism of an invertebrate nitric oxide synthase gene. Gene 232, 25–34 (1999)
Holt, R.A., Subramanian, G.M., Halpern, A., Sutton, G.G., Charlab, R., Nusskern, D.R., Wincker, P., Clark, A.G., Ribeiro, J.M., Wides, R., Salzberg, S.L., Loftus, B., Yandell, M., Majoros, W.H., Rusch, D.B., Lai, Z., Kraft, C.L., Abril, J.F., Anthouard, V., Arensburger, P., Atkinson, P.W., Baden, H., de Berardinis, V., Baldwin, D., Benes, V., Biedler, J., Blass, C., Bolanos, R., Boscus, D., Barnstead, M., Cai, S., Center, A., Chaturverdi, K., Christophides, G.K., Chrystal, M.A., Clamp, M., Cravchik, A., Curwen, V., Dana, A., Delcher, A., Dew, I., Evans, C.A., Flanigan, M., Grundschober-Freimoser, A., Friedli, L., Gu, Z., Guan, P., Guigo, R., Hillenmeyer, M.E., Hladun, S.L., Hogan, J.R., Hong, Y.S., Hoover, J., Jaillon, O., Ke, Z., Kodira, C., Kokoza, E., Koutsos, A., Letunic, I., Levitsky, A., Liang, Y., Lin, J.J., Lobo, N.F., Lopez, J.R., Malek, J.A., McIntosh, T.C., Meister, S., Miller, J., Mobarry, C., Mongin, E., Murphy, S.D., O’Brochta, D.A., Pfannkoch, C., Qi, R., Regier, M.A., Remington, K., Shao, H., Sharakhova, M.V., Sitter, C.D., Shetty, J., Smith, T.J., Strong, R., Sun, J., Thomasova, D., Ton, L.Q., Topalis, P., Tu, Z., Unger, M.F., Walenz, B., Wang, A., Wang, J., Wang, M., Wang, X., Woodford, K.J., Wortman, J.R., Wu, M., Yao, A., Zdobnov, E.M., Zhang, H., Zhao, Q., Zhao, S., Zhu, S.C., Zhimulev, I., Coluzzi, M., della Torre, A., Roth, C.W., Louis, C., Kalush, F., Mural, R.J., Myers, E.W., Adams, M.D., Smith, H.O., Broder, S., Gardner, M.J., Fraser, C.M., Birney, E., Bork, P., Brey, P.T., Venter, J.C., Weissenbach, J., Kafatos, F.C., Collins, F.H., Hoffman, S.L.: The genome sequence of the malaria mosquito Anopheles gambiae. Science 298, 129–149 (2002)
Krzywinski, J., Nusskern, D.R., Kern, M.K., Besansky, N.J.: Isolation and characterization of Y chromosome sequences from the African malaria mosquito Anopheles gambiae. Genetics 166, 1291–1302 (2004)
Sharakhova, M.V., Xia, A., McAlister, S.I., Sharakhov, I.V.: A standard cytogenetic photomap for the mosquito Anopheles stephensi (Diptera: Culicidae): application for physical mapping. J. Med. Entomol. 43, 861–866 (2006)
Tsy, J.M.P., Duchemin, J.B., Marrama, L., Rabarison, P., Le Goff, G., Rajaonarivelo, V., Robert, V.: Distribution of the species of the Anopheles gambiae complex and first evidence of Anopheles merus as a malaria vector in Madagascar. Malar J. 2, 33 (2003)
Garcia, B.A., Caccone, A., Mathiopoulos, K.D., Powell, J.R.: Inversion monophyly in African anopheline malaria vectors. Genetics 143, 1313–1320 (1996)
Besansky, N.J., Krzywinski, J., Lehmann, T., Simard, F., Kern, M., Mukabayire, O., Fontenille, D., Toure, Y.T., Sagnon, N.F.: Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis: evidence from multilocus DNA sequence variation. Proc. Natl. Acad. Sci. USA 100, 10818–10823 (2003)
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Xia, A., Sharakhova, M.V., Sharakhov, I.V. (2007). Reconstructing an Inversion History in the Anopheles Gambiae Complex. In: Tesler, G., Durand, D. (eds) Comparative Genomics. RECOMB-CG 2007. Lecture Notes in Computer Science(), vol 4751. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74960-8_11
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DOI: https://doi.org/10.1007/978-3-540-74960-8_11
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