[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Skip to main content

Controller Design Method of Gene Networks by Network Learning and Its Performance Evaluation

  • Conference paper
Neural Information Processing (ICONIP 2007)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 4985))

Included in the following conference series:

  • 1564 Accesses

Abstract

Investigating gene regulatory networks is important to understand mechanism of cellular functions. Recently, construction of gene networks having desired functions is of interest to many researchers because it is a complementary approach to understanding gene regulatory networks, and it could be the first step to control living cells. A synthesis method of gene networks based on given gene expression pattern sequences by network learning was already proposed. The objective of the paper is to apply the synthesis method to a controller design problem and to evaluate performance of the method. Some numerical experiments are given to evaluate the performance of the proposed method.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Elowitz, M.B., Leibler, S.: A synthetic oscillatory network of transcriptional regulators. Nature 403, 335–338 (2000)

    Article  Google Scholar 

  2. Hasty, J., Isaacs, F.: Designer gene networks: Towards fundamental cellular control. Chaos 11(1), 207–220 (2001)

    Article  MATH  Google Scholar 

  3. Ichinose, N., Aihara, K.: A gene network model and its design. In: The 15th Work shop on Circuit and Systems, pp. 589–593 (2002) (in Japanese)

    Google Scholar 

  4. Nakayama, H., Tanaka, H., Ushio, T.: The formulation of the control of an expression pattern in a gene network by propositional calculus. Journal of Theoretical Biology 240(3), 443–450 (2006)

    Article  MathSciNet  Google Scholar 

  5. Mori, Y., Kuroe, Y., Mori, T.: A synthesis method of gene networks based on gene expression by network learning. In: Proc. of SICE-ICASE International Joint Conference, pp. 4545–4550 (2006)

    Google Scholar 

  6. Glass, L.: Classification of biological networks by their qualitative dynamics. Journal of Theoretical Biology 54, 85–107 (1975)

    Article  Google Scholar 

  7. Ishikawa, M.: Structural learning with forgetting. Neural Networks 9(3), 509–521 (1996)

    Article  Google Scholar 

  8. Kuroe, Y., Ikeda, H., Mori, T.: Identification of nonlinear dynamical systems by recurrent high-order neural networks. In: Proc. of IEEE Int. Conf. on Syst. Man Cybern., vol. 1, pp. 70–75 (1997)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Masumi Ishikawa Kenji Doya Hiroyuki Miyamoto Takeshi Yamakawa

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Mori, Y., Kuroe, Y., Mori, T. (2008). Controller Design Method of Gene Networks by Network Learning and Its Performance Evaluation. In: Ishikawa, M., Doya, K., Miyamoto, H., Yamakawa, T. (eds) Neural Information Processing. ICONIP 2007. Lecture Notes in Computer Science, vol 4985. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-69162-4_84

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-69162-4_84

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-69159-4

  • Online ISBN: 978-3-540-69162-4

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics