Abstract
Histopathological whole slide images of the same organ stained with the same dye exhibit substantial inter-slide variation due to the manual preparation and staining process as well as due to inter-individual variability. In order to improve the generalization ability of a classification model on data from kidney pathology, we investigate a domain adaptation approach where a classifier trained on data from the source domain is presented a small number of user-labeled samples from the target domain. Domain adaptation resulted in improved classification performance, especially when combined with an interactive labeling procedure.
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References
Fioretto, P., Mauer, M.: Histopathology of diabetic nephropathy. Semin. Nephrol. 27(2), 195–207 (2007)
Macenko, M., Niethammer, M., Marron, J.S., Borland, D., Woosley, J.T., Guan,X., Schmitt, C., Thomas, N.E.: A method for normalizing histology slides for quantitative analysis. In: Proceedings of ISBI 2009, pp. 1107–1110 (2009)
Kato, T., Relator, R., Ngouv, H., Hirohashi, Y., Takaki, O., Kakimoto, T., Okada, K.: Segmental hog: new descriptor for glomerulus detection in kidneymicroscopy image. BMC Bioinform. 16(1), 316 (2015)
Herve, N., Servais, A., Thervet, E., Olivo-Marin, J.C., Meas-Yedid, V.: Statistical color texture descriptors for histological images analysis. In: Proceedings of ISBI 2011, pp. 724–727 (2011)
Jhuo, I.H., Liu, D., Lee, D.T., Chang, S.F.: Robust visual domain adaptation with low-rank reconstruction. In: Proceedings of CVPR 2012
Persello, C.: Interactive domain adaptation for the classification of remote sensing images using active learning. IEEE Trans. Geosci. Remote Sens. 10(4), 736–740 (2013)
Ojala, T., Pietikäinen, M., Mäenpää, T.: Multiresolution Gray-Scale and rotation invariant texture classification with local binary patterns. IEEE Trans. Pattern Anal. Mach. Intell. 24(7), 971–987 (2002)
Sánchez, J., Perronnin, F., Mensink, T., Verbeek, J.J.: Image classification with the fisher vector: theory and practice. Int. J. Comput. Vis. 105(3), 222–245 (2013)
Wang, J.G., Li, J., Yau, W.Y., Sung, E.: Boosting dense SIFT descriptors and shape contexts of face images for gender recognition. In: Proceedings of CVPR 2010, pp. 96–102 (2010)
Boor, P., Bábíčková, J., Steegh, F.: Role of platelet-derived growth factor-cc in capillary rarefaction in renal fibrosis. Am. J. Pathol. 185(8), 2132–2142 (2015)
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Gadermayr, M., Strauch, M., Klinkhammer, B.M., Djudjaj, S., Boor, P., Merhof, D. (2016). Domain Adaptive Classification for Compensating Variability in Histopathological Whole Slide Images. In: Campilho, A., Karray, F. (eds) Image Analysis and Recognition. ICIAR 2016. Lecture Notes in Computer Science(), vol 9730. Springer, Cham. https://doi.org/10.1007/978-3-319-41501-7_69
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DOI: https://doi.org/10.1007/978-3-319-41501-7_69
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