Abstract
This paper introduces a novel pipeline for synthesizing realistic 3D+t CSPAMM cardiac tagged magnetic resonance (MR) images. The proposed framework is based on the combination of an electro-mechanical model for generating cardiac deformation fields and a template tagging recording for assigning realistic voxel intensities. We developed a spatio-temporal alignment strategy for mapping voxel positions in the simulation space to the template recording space. As a preliminary result, we generated a synthetic dataset of a normal heart, and further compared the performance of two state-of-the-art cardiac motion tracking algorithms using this synthetic data. In this study, we aim at showing the capability of the proposed pipeline to simulate realistic cardiac tagged MR images, and its extension to more synthetic cases especially pathological ones are currently left to future work.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Zhou, Y., Bernard, O., Saloux, E., Manrique, A., Allain, P., Makram-Ebeid, S., De Craene, M.: 3D harmonic phase tracking with anatomical regularization. Med. Image Anal. 26(1), 70–81 (2015)
Crum, W., Berry, E., Ridgway, J., Sivananthan, U., Tan, L., Smith, M.: Simulation of two-dimensional tagged MRI. J. Magn. Reson. Imaging 7(2), 416–424 (1997)
Waks, E., Prince, J., Douglas, A.: Cardiac motion simulator for tagged MRI. In: Proceedings of the Workshop on Mathematical Methods in Biomedical Image Analysis, pp. 182–191. IEEE (1996)
Crum, W., Berry, E., Ridgway, J., Sivananthan, U., Tan, L., Smith, M.: Frequency-domain simulation of MR tagging. J. Magn. Reson. Imaging 8(5), 1040–1050 (1998)
Sermesant, M., Moireau, P., Camara, O., Sainte-Marie, J., Andriantsimiavona, R., Cimrman, R., Hill, D., Chapelle, D., Razavi, R.: Cardiac function estimation from MRI using a heart model and data assimilation: advances and difficulties. Med. Image Anal. 10(4), 642–656 (2006)
Clarysse, P., Tafazzoli, J., Delachartre, P., Croisille, P.: Simulation based evaluation of cardiac motion estimation methods in tagged-MR image sequences. J. Cardiovasc. Magn. Reson. 13(1), 1–1 (2011)
Alessandrini, M., De Craene, M., Bernard, O., Giffard-Roisin, S., Allain, P., Weese, J., Saloux, E., Delingette, H., Sermesant, M., D’hooge, J.: A pipeline for the generation of realistic 3D synthetic echocardiographic sequences: methodology and open-access database. IEEE Trans. Med. Imaging 34(7), 1436–1451 (2015)
Prakosa, A., Sermesant, M., Delingette, H., Marchesseau, S., Saloux, E., Allain, P., Villain, N., Ayache, N.: Generation of synthetic but visually realistic time series of cardiac images combining a biophysical model and clinical images. IEEE Trans. Med. Imaging 32(1), 99–109 (2013)
Marchesseau, S., Delingette, H., Sermesant, M., Ayache, N.: Fast parameter calibration of a cardiac electromechanical model from medical images based on the unscented transform. Biomech. Model. Mechanobiol. 12(4), 815–831 (2013)
Somphone, O., De Craene, M., Ardon, R., Mory, B., Allain, P., Gao, H., D’hooge, J., Marchesseau, S., Sermesant, M. Delingette, H., et al.: Fast myocardial motion and strain estimation in 3D cardiac ultrasound with sparse demons. In: IEEE 10th International Symposium on Biomedical Imaging (ISBI), pp. 1182–1185. IEEE (2013)
Tobon-Gomez, C., De Craene, M., Mcleod, K., Tautz, L., Shi, W., Hennemuth, A., Prakosa, A., Wang, H., Carr-White, G., Kapetanakis, S., et al.: Benchmarking framework for myocardial tracking and deformation algorithms: an open access database. Med. Image Anal. 17(6), 632–648 (2013)
Fischer, S., McKinnon, G., Maier, S., Boesiger, P.: Improved myocardial tagging contrast. Magn. Reson. Med. 30(2), 191–200 (1993)
Rutz, A., Ryf, S., Plein, S., Boesiger, P., Kozerke, S.: Accelerated whole-heart 3D CSPAMM for myocardial motion quantification. Magn. Reson. Med. 59(4), 755–763 (2008)
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2016 Springer International Publishing AG
About this paper
Cite this paper
Zhou, Y., De Craene, M., Somphone, O., Sermesant, M., Bernard, O. (2016). Generation of Realistic 4D Synthetic CSPAMM Tagged MR Sequences for Benchmarking Cardiac Motion Tracking Algorithms. In: Tsaftaris, S., Gooya, A., Frangi, A., Prince, J. (eds) Simulation and Synthesis in Medical Imaging. SASHIMI 2016. Lecture Notes in Computer Science(), vol 9968. Springer, Cham. https://doi.org/10.1007/978-3-319-46630-9_11
Download citation
DOI: https://doi.org/10.1007/978-3-319-46630-9_11
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-46629-3
Online ISBN: 978-3-319-46630-9
eBook Packages: Computer ScienceComputer Science (R0)