Abstract
We present an integrated model of mitral valve coupled with the left ventricle. The model is derived from clinical images and takes into account of the important valvular features, left ventricle contraction, nonlinear soft tissue mechanics, fluid structure interaction, and the MV-LV interaction. This model is compared with a corresponding mitral-tube model, and differences in the results are discussed. Although the model is a step closer towards simulating physiological realistic situation, further work is required to ensure that the highly complex valvular-ventricular interaction, and the fluid-structure interaction, can be reliably represented.
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Acknowledgement
This work is funded by the UK EPSRC (EP/I1029990), and the British Heart Foundation (PG/14/64/31043, PG/11/2/28474). B.E.G. acknowledges research support from the American Heart Association (AHA award 10 SDG4320049), the National Institutes of Health (award HL117063), and the National Science Foundation (awards DMS 1016554 and ACI 1047734).
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Gao, H., Qi, N., Ma, X., Griffith, B.E., Berry, C., Luo, X. (2015). Fluid-Structure Interaction Model of Human Mitral Valve within Left Ventricle. In: van Assen, H., Bovendeerd, P., Delhaas, T. (eds) Functional Imaging and Modeling of the Heart. FIMH 2015. Lecture Notes in Computer Science(), vol 9126. Springer, Cham. https://doi.org/10.1007/978-3-319-20309-6_38
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