Abstract
Joint segmentation and quantification of main coronary vessels are important to the diagnosis and intraoperative treatment of coronary artery disease. They can help clinicians decide whether to carry out coronary revascularization and choose the interventional stent. However, joint segmentation and quantification in a framework is still challenging because of intrinsic distinction of optimization objects for these two tasks. In this paper, we propose a dual-branch multi-scale attention network (DMAN) to achieve synergistic optimization process in a framework. Our DMAN consists of a nested residual module and a attentive regression module. The nested residual module is used to extract and aggregate multi-level and multi-scale features. The attentive regression module introduces a two-phase attention block to express interactive correlation of separated regions and capture the informativeness of the important region in the image. Our DMAN is evaluated over 1893 X-ray coronary angiography images collected from 529 subjects. DMAN achieves the dice coefficient of 0.916 for segmentation and the MAE of 1.30 ± 0.62 mm for quantification.
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References
Sianos, G., et al.: The SYNTAX score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 1(2), 219–227 (2005)
Halon, D.A., Sapoznikov, D., Lewis, B.S., Gotsman, M.S.: Localization of lesions in the coronary circulation. Am. J. Cardiol. 52(8), 921–926 (1983)
Vogel, R.A.: Assessing stenosis significance by coronary arteriography: are the best variables good enough? J. Am. Coll. Cardiol. 12(3), 692–693 (1988)
Fioranelli, M., Gonnella, C., Tonioni, S., D’Errico, F., Carbone, M.: Clinical anatomy of the coronary circulation. In: Imaging Coronary Arteries, pp. 1–11 (2013)
Rittger, H., Schertel, B., Schmidt, M., Justiz, J., Brachmann, J., Sinha, A.M.: Three-dimensional reconstruction allows accurate quantification and length measurements of coronary artery stenoses. EuroIntervention 5(1), 127–132 (2009)
Tomasello, S. D., Costanzo, L., Galassi, A. R.: Quantitative coronary angiography in the interventional cardiology. In: Advances in the Diagnosis of Coronary Atherosclerosis (2011)
Garrone, P., et al.: Quantitative coronary angiography in the current era: principles and applications. J. Intervent. Cardiol 22(6), 527–536 (2009)
Jun, T.J., Kweon, J., Kim, Y.H., Kim, D.: T-net: nested encoder-decoder architecture for the main vessel segmentation in coronary angiography. Neural Netw. 128, 216–233 (2020)
Qin, B., et al.: Accurate vessel extraction via tensor completion of background layer in X-ray coronary angiograms. Pattern Recogn. 87, 38–54 (2019)
Cervantes-Sanchez, F., Cruz-Aceves, I., Hernandez-Aguirre, A., Hernandez-Gonzalez, M.A., Solorio-Meza, S.E.: Automatic segmentation of coronary arteries in X-ray angiograms using multiscale analysis and artificial neural networks. Appl. Sci. 9(24), 5507 (2019)
Hao, D., et al.: Sequential vessel segmentation via deep channel attention network. Neural Netw. 128, 172–187 (2020)
Cong, W., Yang, J., Ai, D., Chen, Y., Liu, Y., Wang, Y.: Quantitative analysis of deformable model-based 3-D reconstruction of coronary artery from multiple angiograms. IEEE Trans. Biomed. Eng. 62(8), 2079–2090 (2015)
Janssen, J.P., Rares, A., Tuinenburg, J.C., Koning, G., Lansky, A.J., Reiber, J.H.: New approaches for the assessment of vessel sizes in quantitative vascular X-ray analysis. Int. J. Cardiovasc. Imaging 26(3), 259–271 (2010)
Wan, T., Feng, H., Tong, C., Li, D., Qin, Z.: Automated identification and grading of coronary artery stenoses with X-ray angiography. Comput. Methods Prog. Biomed. 167, 13–22 (2018)
Zhang, D., Yang, G., Zhao, S., Zhang, Y., Zhang, H., Li, S.: Direct quantification for coronary artery stenosis using multiview learning. In: International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 449–457 (2019)
Zhang, D., et al.: Direct quantification for coronary artery stenosis using multiview learning. IEEE Trans. Med. Imaging 39(12), 4322–4334 (2020)
Qin, X., Zhang, Z., Huang, C., Dehghan, M., Zaiane, O.R., Jagersand, M.: U2-Net: going deeper with nested U-structure for salient object detection. Pattern Recogn. 106, 107404 (2020)
Zhang, H., Goodfellow, I., Metaxas, D., Odena, A.: Self-attention generative adversarial networks. In: International Conference on Machine Learning, pp. 7354–7363 (2019)
Yang, Z., Yang, D., Dyer, C., He, X., Smola, A., Hovy, E.: Hierarchical attention networks for document classification. In: The 2016 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, pp. 1480–1489 (2016)
Baxter, J.: A model of inductive bias learning. J. Artif. Intell. Res. 12, 149–198 (2000)
Maurer, A., Pontil, M., Romera-Paredes, B.: The benefit of multitask representation learning. J. Mach. Learn. Res. 17(81), 1–32 (2016)
Yang, S., Kweon, J., Kim, Y. H.: Major vessel segmentation on x-ray coronary angiography using deep networks with a novel penalty loss function. In: International Conference on Medical Imaging with Deep Learning (2019)
Yang, S., et al.: Deep learning segmentation of major vessels in X-ray coronary angiography. Sci. Rep. 9(1), 1–11 (2019)
Zhu, X., Cheng, Z., Wang, S., Chen, X., Lu, G.: Coronary angiography image segmentation based on PSPNet. Comput. Methods Prog. Biomed. 200, 105897 (2020)
Xian, Z., Wang, X., Yan, S., Yang, D., Chen, J., Peng, C.: Main coronary vessel segmentation using deep learning in smart medical. Math. Prob. Eng. 2020, 1–9 (2020)
Krizhevsky, A., Sutskever, I., Hinton, G.E.: Imagenet classification with deep convolutional neural networks. Adv. Neural Inf. Process. Syst. 25, 1097–1105 (2012)
Zhen, X., Wang, Z., Islam, A., Bhaduri, M., Chan, I., Li, S.: Direct estimation of cardiac bi-ventricular volumes with regression forests. In: International Conference on Medical Image Computing and Computer-Assisted Intervention, pp. 586–593 (2014)
Xue, W., Islam, A., Bhaduri, M., Li, S.: Direct multitype cardiac indices estimation via joint representation and regression learning. IEEE Trans. Med. Imaging 36(10), 2057–2067 (2017)
Acknowledgement
This work was supported by the National Natural Science Foundation of China under Grant U1908211 and Key Program for International Cooperation Projects of Guangdong Province under Grant 2018A050506031.
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Zhang, H., Zhang, D., Gao, Z., Zhang, H. (2021). Joint Segmentation and Quantification of Main Coronary Vessels Using Dual-Branch Multi-scale Attention Network. In: de Bruijne, M., et al. Medical Image Computing and Computer Assisted Intervention – MICCAI 2021. MICCAI 2021. Lecture Notes in Computer Science(), vol 12901. Springer, Cham. https://doi.org/10.1007/978-3-030-87193-2_35
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