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Physiological Evaluation of a Non-invasive Wearable Vagus Nerve Stimulation (VNS) Device

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Advances in Human Factors in Wearable Technologies and Game Design (AHFE 2019)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 973))

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Abstract

Recent clinical studies suggest that Vagus nerve stimulation (VNS) may be a safe and potentially effective for disorder related to heart. In the rise of wearable medical devices, non-invasive wearable VNS devices are available to treatment of disorders related to the central nervous system. The goal of this study was to investigate the effects of VNS devices on physiological parameters of human. AMO+ is a wearable VNS device that was worn to the neck as a necklace. ECG (Electrocardiogram) and EEG (Electroencephalogram) of 30 healthy persons are measured in Center for Medical Metrology, Korea Research Institute of Standards and Science, Daejeon, South Korea. Wireless Bionomadix (Biopac Systems, Goleta, CA) RSPEC-R used for measuring ECG and EEG2-R as used to measure EEG. EEG electrodes are placed in F3 and F4 position of head as per 10/20 System. Acqknowledge Ver. 14 used for data analysis. EEG α, β, θ, δ power spectrums are extracted from raw EEG signals. HR (Heart Rate), HF (High Frequency), LF (Low Frequency) features are extracted from raw ECG data. Data was taken before using VNS deice and after one hour of using wearable AMO VNS device. All data was taken in resting state. Statistical analysis was done by IBM SPSS Ver. 23.0. No significant difference of HR is found between cases of before using VNS device and after using VNS device. A significant difference found in case of HF power of ECG. As ECG HF power reflects the parasympathetic nervous system activity, HF power increase indicates improvement of parasympathetic nervous system activity. No significant difference of EEG α, β, θ power spectrums except δ power is found between cases of before using VNS device and after using VNS device. Wearable AMO+ VNS stimulation is expected to improve the parasympathetic nervous system activity.

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References

  1. Berthoud, H.R., Neuhuber, W.L.: Functional and chemical anatomy of the afferent vagal system (in eng). Auton. Neurosci. 85(1–3), 1–17 (2000)

    Article  Google Scholar 

  2. Yuan, H., Silberstein, S.D.: Vagus nerve and vagus nerve stimulation, a comprehensive review: Part I 56(1), 71–78 (2016)

    Google Scholar 

  3. Bailey, P., Bremer, F.: A sensory cortical representation of the vagus nerve: with a note on the effects of low blood pressure on the cortical electrogram. 1(5), 405–412 (1938)

    Google Scholar 

  4. Zanchetti, A., Wang, S.C., Moruzzi, G.: The effect of vagal afferent stimulation on the EEG pattern of the cat (in eng). Electroencephalogr. Clin. Neurophysiol. 4(3), 357–361 (1952)

    Article  Google Scholar 

  5. Magnes, J., Moruzzi, G., Pompeiano, O.: Synchronization of the EEG produced by low-frequncy electrical stimulation of the region of the solitary tract. 99(1), 33–67 (1961)

    Google Scholar 

  6. Yuan, H., Silberstein, S.D., Pain, F.: Vagus nerve and vagus nerve stimulation, a comprehensive review: Part II. 56(2), 259–266 (2016)

    Google Scholar 

  7. Schachter, S.C., Saper, C.B.: Vagus nerve stimulation. 39(7), 677–686 (1998)

    Google Scholar 

  8. Stavrakis, S., et al.: Low-level transcutaneous electrical vagus nerve stimulation suppresses atrial fibrillation. 65(9), 867–875 (2015)

    Google Scholar 

  9. Howland, R.H.: New developments with vagus nerve stimulation therapy. 52(3), 11–14 (2014)

    Google Scholar 

  10. Ben‐Menachem, E., Revesz, D., Simon, B., Silberstein, S.J.: Surgically implanted and non‐invasive vagus nerve stimulation: a review of efficacy, safety and tolerability. 22(9), 1260–1268 (2015)

    Google Scholar 

  11. DeGiorgio, C.M., et al.: Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures (in eng). Epilepsia 41(9), 1195–1200 (2000)

    Article  Google Scholar 

  12. Boon, P., et al.: A prospective, multicenter study of cardiac-based seizure detection to activate vagus nerve stimulation. 32, 52–61 (2015)

    Google Scholar 

  13. Mertens, A., Raedt, R., Gadeyne, S., Carrette, E., Boon, P., Vonck, K.J.: Recent advances in devices for vagus nerve stimulation. 15(8), 527–539 (2018)

    Google Scholar 

  14. Malliani, A., Lombardi, F., Pagani, M.: Power spectrum analysis of heart rate variability: a tool to explore neural regulatory mechanisms. Br. Heart J. 71(1), 1–2 (1994)

    Article  Google Scholar 

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Acknowledgments

The AMO Lab (www.amo-lab.com) supported this work.

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Correspondence to Se Jin Park .

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Park, S.J., Hong, S., Kim, D., Hussain, I., Seo, Y., Kim, M.K. (2020). Physiological Evaluation of a Non-invasive Wearable Vagus Nerve Stimulation (VNS) Device. In: Ahram, T. (eds) Advances in Human Factors in Wearable Technologies and Game Design. AHFE 2019. Advances in Intelligent Systems and Computing, vol 973. Springer, Cham. https://doi.org/10.1007/978-3-030-20476-1_7

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  • DOI: https://doi.org/10.1007/978-3-030-20476-1_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-20475-4

  • Online ISBN: 978-3-030-20476-1

  • eBook Packages: EngineeringEngineering (R0)

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