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Characterizing Parkinson’s Disease from Speech Samples Using Deep Structured Learning

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Proceedings of the Tenth International Conference on Soft Computing and Pattern Recognition (SoCPaR 2018) (SoCPaR 2018)

Part of the book series: Advances in Intelligent Systems and Computing ((AISC,volume 942))

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Abstract

An early detection of neurodegenerative diseases, such as Parkinson’s disease, can improve therapy effectiveness and, by consequence, the patient’s quality of life. This paper proposes a new methodology for automatic classification of voice samples regarding the presence of acoustic patterns of Parkinson’s disease, using a deep structured neural network. This is a low cost non-invasive approach that can raise alerts in a pre-clinical stage. Aiming to a higher diagnostic detail, it is also an objective to accurately estimate the stage of evolution of the disease allowing to understand in what extent the symptoms have developed. Therefore, two types of classification problems are explored: binary classification and multiclass classification. For binary classification, a deep structured neural network was developed, capable of correctly diagnosing 93.4% of cases. For the multiclass classification scenario, in addition to the deep neural network, a K-nearest neighbour algorithm was also used to establish a reference for comparison purposes, while using a common database. In both cases the original feature set was optimized using principal component analysis and the results showed that the proposed deep structure neural network was able to provide more accurate estimations about the disease’s stage, reaching a score of 84.7%. The obtained results are promising and create the motivation to further explore the model’s flexibility and to pursue better results.

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References

  1. Ho, A.K., Iansek, R., Marigliani, C., Bradshaw, J.L., Gates, S.: Speech impairment in a large sample of patients with Parkinson’s disease. Behav. Neurol. 11, 131–137 (1998)

    Article  Google Scholar 

  2. Ramig, L.O., Fox, C., Sapir, S.: Speech treatment for Parkinson’s disease. Expert Rev. Neurother. 8, 297–309 (2008)

    Article  Google Scholar 

  3. Khemphila, A., Boonjing, V.: Parkinsons disease classification using neural network and feature selection. Int. J. Math. Phys. Electr. Comput. Eng. 6, 377–380 (2012)

    Google Scholar 

  4. Hirsch, L., Jette, N., Frolkis, A., Steeves, T., Pringsheim, T.: The incidence of Parkinson’s disease: a systematic review and meta-analysis. Neuroepidemiology 46, 292–300 (2016)

    Article  Google Scholar 

  5. Neurological disorders: public health challenges. World Health Organization (2006)

    Google Scholar 

  6. Müller, J., Wenning, G.K., Verny, M., McKee, A., Chaudhuri, K.R., Jellinger, K., Poewe, W., Litvan, I.: Progression of dysarthria and dysphagia in postmortem-confirmed parkinsonian disorders. Arch. Neurol. 58, 259–264 (2001)

    Article  Google Scholar 

  7. Liu, L., Luo, X.-G., Dy, C.-L., Ren, Y., Feng, Y., Yu, H.-M., Shang, H., He, Z.-Y.: Characteristics of language impairment in Parkinson’s disease and its influencing factors. Transl. Neurodegener. 4, 2 (2015)

    Article  Google Scholar 

  8. Teixeira, J., Soares, L., Martins, P., Coelho, L., Lopes, C.: Towards an objective criteria for the diagnosis of Parkinson disease based on speech assessment. Presented at the XXXV Congresso Anual de la Sociedad Espanola de Ingenierıa Biomedica, Bilbao (2017)

    Google Scholar 

  9. Norel, R., Agurto, C., Rice, J.J., Ho, B.K., Cecchi, G.A.: Speech-based identification of L-DOPA ON/OFF state in Parkinson’s Disease subjects. BioRxiv Prepr. 420422 (2018)

    Google Scholar 

  10. Zhang, Y.N.: Can a smartphone diagnose Parkinson disease? A deep neural network method and telediagnosis system implementation. Park. Dis. (2017)

    Google Scholar 

  11. Braga, D., Madureira, A.M., Coelho, L., Abraham, A.: Neurodegenerative diseases detection through voice analysis. In: Abraham, A., Muhuri, P.K., Muda, A.K., Gandhi, N. (eds.) Hybrid Intelligent Systems, pp. 213–223. Springer, Heidelberg (2018)

    Chapter  Google Scholar 

  12. LeCun, Y., Bengio, Y., Hinton, G.: Deep learning. Nature 521, 436–444 (2015)

    Article  Google Scholar 

  13. Gil, D., Magnus, J.: Diagnosing Parkinson by using artificial neural networks and support vector machines. Glob. J. Comput. Sci. Technol. 9, 63–71 (2009)

    Google Scholar 

  14. Saloni, R.K., Gupta, A.K.: Detection of Parkinson disease using clinical voice data mining. Int. J. Circuits Syst. Signal Process. 9 (2015)

    Google Scholar 

  15. Tsanas, A., Little, M.A., McSharry, P.E., Spielman, J., Ramig, L.O.: Novel speech signal processing algorithms for high-accuracy classification of Parkinson’s disease. IEEE Trans. Biomed. Eng. 59, 1264–1271 (2012)

    Article  Google Scholar 

  16. Proença, J., Veiga, A., Candeias, S., Lemos, J., Januário, C., Perdigão, F.: Characterizing Parkinson’s disease speech by acoustic and phonetic features. In: Baptista, J., Mamede, N., Candeias, S., Paraboni, I., Pardo, T.A.S., Volpe Nunes, M.d.G. (eds.) Computational Processing of the Portuguese Language, pp. 24–35. Springer, Heidelberg (2014)

    Google Scholar 

  17. Sakar, B.E., Isenkul, M.E., Sakar, C.O., Sertbas, A., Gurgen, F., Delil, S., Apaydin, H., Kursun, O.: Collection and analysis of a Parkinson speech dataset with multiple types of sound recordings. IEEE J. Biomed. Health Inform. 17, 828–834 (2013)

    Article  Google Scholar 

  18. Abadi, M., Agarwal, A., Barham, P., Brevdo, E., Chen, Z., Citro, C., Corrado, G.S., Davis, A., Dean, J., Devin, M., Ghemawat, S., Goodfellow, I., Harp, A., Irving, G., Isard, M., Jia, Y., Jozefowicz, R., Kaiser, L., Kudlur, M., Vasudevan, V., Viegas, F., Vinyals, O., Warden, P., Wattenberg, M., Wicke, M., Yu, Y., Zheng, X.: TensorFlow: Large-Scale Machine Learning on Heterogeneous Distributed Systems. ArXiv160304467 Cs (2016)

    Google Scholar 

  19. Ranzato, M., Poultney, C., Chopra, S., LeCun, Y.: Efficient learning of sparse representations with an energy-based model. In: Proceedings of the 19th International Conference on Neural Information Processing Systems. pp. 1137–1144. MIT Press, Cambridge (2006)

    Google Scholar 

  20. Glorot, X., Bordes, A., Bengio, Y.: Deep sparse rectifier neural networks. In: Proceedings of the 14th International Conference on Artificial Intelligence and Statistics, pp. 315–323. Fort Lauderdale, Florida (2011)

    Google Scholar 

  21. Srivastava, N., Hinton, G., Krizhevsky, A., Sutskever, I., Salakhutdinov, R.: Dropout: a simple way to prevent neural networks from overfitting. J. Mach. Learn. Res. 15, 1929–1958 (2014)

    MathSciNet  MATH  Google Scholar 

  22. Arlot, S., Celisse, A.: A survey of cross-validation procedures for model selection. Stat. Surv. 4, 40–79 (2010)

    Article  MathSciNet  Google Scholar 

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Correspondence to Lígia Sousa .

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Sousa, L., Braga, D., Madureira, A., Coelho, L., Renna, F. (2020). Characterizing Parkinson’s Disease from Speech Samples Using Deep Structured Learning. In: Madureira, A., Abraham, A., Gandhi, N., Silva, C., Antunes, M. (eds) Proceedings of the Tenth International Conference on Soft Computing and Pattern Recognition (SoCPaR 2018). SoCPaR 2018. Advances in Intelligent Systems and Computing, vol 942. Springer, Cham. https://doi.org/10.1007/978-3-030-17065-3_14

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