Abstract
During the last several years Professor Rozenberg and I have been working closely together to try to unravel the secrets of complex DNA manipulations in ciliates. His creative and incisive analysis has given us a fresh perspective on the remarkable acrobatics that ciliates perform with their DNA gene sequences. I am pleased to contribute this paper on the structure of germline genes, which ciliates process in phenomenal ways, as an expression of my appreciation and admiration for his intelligence and energy in the quest to explain the extraordinary DNA gymnastics that the tiny ciliates perform.
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References
Bierbaum, P., Dönho., T. and Klein, A. 1991. Macronuclear and Micronuclear Configurations of a Gene Encoding the Protein Synthesis Elongation Factor EF1αin Stylonychia lemnae. Mol. Microbiol. 5: 1567–1575.
DuBois, M.L. and Prescott, D.M. 1995. Scrambling of the Actin I Gene in Two Oxytricha Species. Proc. Natl. Acad. Sci. USA 92: 3888–3892.
Foissner, W. and Berger, H. 1999. Identification and Ontogenesis of the nomen nudum Ypotrichs (Protozoa: Ciliophora) Oxytricha nova (= Sterkiella nova sp. n.) and O. trifallax (= S. histriomuscorum). Acta Protozool. 38: 215–248.
Hoffman, D.C., and Prescott, D.M. 1997. Evolution of Internal Eliminated Segments and Scrambling in the Micronuclear Gene Encoding DNA Polymerase α in Two Oxytricha Species. Nucl. Acids Res. 25: 1883–1889.
Hogan, D., Hewitt, E., Orr, K. and Prescott, D.M. 2001. Evolution of IESs and Scrambling of the Actin I Gene in Hypotrichous Ciliates. Proc. Natl. Acad. Sci. USA, submitted.
Landweber, L.F., Kuo, T-C. and Curtis, E.A. 2000. Evolution and Assembly of an Extremely Scrambled Gene. Proc. Natl. Acad. Sci. USA 97: 3298–3303.
Prescott, D.M., Prescott, J.D. and Prescott, R.M. 2001a. Coding Properties of Macronuclear DNA Molecules in Sterkiella nova (Oxytricha nova). Gene, submitted.
Prescott, D.M., Ehrenfeucht, A. and Rozenberg, G. 2001b. Molecular Operations for DNA Processing in Hypotrichous Ciliates. Eur. J. Protistol. 37, in press.
Prescott, J.D., DuBois M.L. and Prescott, D.M. 1998. Evolution of the Scrambled Germline Gene Encoding α-telomere Binding Protein in Three Hypotrichous Ciliates. Chromosoma 107: 293–303.
Prescott, D.M. and DuBois, M.L. 1996. Internal Eliminated Segments (IESs) of Oxytrichidae. J. Euk. Microbiol. 43: 432–441.
Prescott, D.M. and Greslin, A.F. 1992. Scrambled Actin I Gene in the Micronucleus of Oxytricha nova. Dev. Genet. 13: 66–74.
Seegmiller, A., Williams, K.R. and Herrick, G. 1997. Two Two-Gene Macronuclear Chromosomes of the Hypotrichous Ciliates Oxytricha fallax and O. trifallax Generated by Alternative Processing of the 81 Locus. Dev. Genet. 20: 348–357.
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Prescott, D.M. (2002). DNA Manipulations in Ciliates. In: Brauer, W., Ehrig, H., Karhumäki, J., Salomaa, A. (eds) Formal and Natural Computing. Lecture Notes in Computer Science, vol 2300. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-45711-9_22
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DOI: https://doi.org/10.1007/3-540-45711-9_22
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