Abstract
Contribution of chemical shift to intermolecular multiple-quantum coherence (iMQC) imaging signals in two-component systems was simulated and discussed using an efficient numerical algorithm based on the Bloch equations with an additional nonlinear term describing distant dipolar field. Numerical simulation switches back and forth between real and Fourier spaces to handle dipolar field effects in three-dimensional sample. The iMQC signals of each component of two-component systems can be obtained respectively when the second pulse of the CRAZED pulse sequence is selective. Simulation results show that chemical shift provides an edge detection method to regions containing spins with chemical shift offset and selected by the second RF pulse, and different gray value is related to different chemical shift in detected regions. These results indicate that chemical shift may provide new imaging information helpful for iMQC magnetic resonance imaging.
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Pohmann, R., von Kienlin, M., Haase, A.: Theoretical Evaluation and Comparison of Fast Chemical Shift Imaging Methods. J. Magn. Reson. 129, 145–160 (1997)
Pauchard, Y., Smith, M.R., Mintchev, M.P.: Improving Geometric Accuracy in the Presence of Susceptibility Difference Artifacts Produced by Metallic Implants in Magnetic Resonance Imaging. IEEE Trans. Med. Imaging 24, 1387–1399 (2005)
Fessler, J.A., Lee, S., Olafsson, V.T., Shi, H.R., Noll, D.C.: Toeplitz-Based Iterative Image Reconstruction for MRI with Correction for Magnetic Field Inhomogeneity. IEEE Trans. Signal Process. 53, 3393–3402 (2005)
Warren, W.S., Ahn, S., Mescher, M., Garwood, M., Ugurbil, K., Richter, W., Rizi, R.R., Hopkins, J., Leigh, J.S.: MR Imaging Contrast Enhancement Based on Intermolecular Zero Quantum Coherences. Science 281, 247–251 (1998)
Zhong, J.H., Chen, Z., Kwok, E.: In vivo Intermolecular Double-Quantum Imaging on a Clinical 1.5(7)T MR Scanner. Magn. Reson. Med. 43, 335–341 (2000)
Zhong, J.H., Chen, Z., Kwok, W.E., Kennedy, S., You, Z.Y.: Optimization of Blood Oxygenation Level-Dependent Sensitivity in Magnetic Resonance Imaging Using Intermolecular Double-Quantum Coherence. J. Magn. Reson. Imaging 16, 733–740 (2002)
Garrett, R.S., Warren, W.S.: Numerical Studies of Intermolecular Multiple Quantum Coherences: High-Resolution NMR in Inhomogeneous Fields and Contrast Enhancement in MRI. J. Magn. Reson. 146, 1–13 (2000)
Enss, T., Ahn, S., Warren, W.S.: Visualizing the Dipolar Field in Solution NMR and MR Imaging: Three-Dimensional Structure Simulations. Chem. Phys. Lett. 305, 101–108 (1999)
Ahn, S., Lisitza, N., Warren, W.S.: Intermolecular Zero-Quantum Coherences of Multi-Component Spin Systems in Solution NMR. J. Magn. Reson. Imaging 133, 266–272 (1998)
Chen, Z., Chen, Z.W., Zhong, J.H.: Quantitative Characterization of Intermolecular Dipolar Interactions of Two-Component Systems in Solution Nuclear Magnetic Resonance. J. Chem. Phys. 115, 10769–10779 (2001)
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© 2006 Springer-Verlag Berlin Heidelberg
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Sun, H., Lin, T., Cai, S., Chen, Z. (2006). Numerical Simulations of Contribution of Chemical Shift in Novel Magnetic Resonance Imaging. In: Jiao, L., Wang, L., Gao, X., Liu, J., Wu, F. (eds) Advances in Natural Computation. ICNC 2006. Lecture Notes in Computer Science, vol 4222. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11881223_46
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DOI: https://doi.org/10.1007/11881223_46
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-45907-1
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