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A Multi-agent System for Modelling Carbohydrate Oxidation in Cell

  • Conference paper
Computational Science and Its Applications – ICCSA 2005 (ICCSA 2005)

Part of the book series: Lecture Notes in Computer Science ((LNTCS,volume 3481))

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Abstract

A cell consists of a large number of components interacting in a dynamic environment. The complexity of interaction among cell components and functions makes design of cell simulations a challenging task for biologists. We posit that the paradigm of agent-oriented software engineering (AOSE), in which complex systems are organized as autonomous software entities (agents) situated in an environment and communicating via high-level languages and protocols (ontologies), may be a natural approach for such models. To evaluate this approach, we constructed a model of cell components involved in the metabolic pathway of carbohydrate oxidation. The agent-oriented organization proved natural and useful in representing three different views of the cell system (functional, dynamic, and static structural) and in supporting bioscientists querying a system very close to their mental model.

This work was supported by Center of Excellence for Research ‘DEWS: Architectures and Design Methodologies for Embedded Controllers, Wireless Interconnect and System-on-chip’ and Italian CIPE project ’Sistemi Cooperativi Multiagente’. Work completed while the second author was on Fulbright leave at University of Oregon.

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Author information

Authors and Affiliations

  1. Dipartimento di Matematica e Informatica, Università di Camerino, Camerino, 62032, Italy

    Flavio Corradini, Emanuela Merelli & Marco Vita

Authors
  1. Flavio Corradini
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  2. Emanuela Merelli
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  3. Marco Vita
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Editor information

Editors and Affiliations

  1. Department of Mathematics and Computer Science, University of Perugia, via Vanvitelli, 1, I-06123, Perugia, Italy

    Osvaldo Gervasi

  2. Department of Computer Science, University of Calgary, 2500 University Drive N.W., T2N 1N4, Calgary, AB, Canada

    Marina L. Gavrilova

  3. William Norris Professor, Head of the Computer Science and Engineering Department, University of Minnesota, USA

    Vipin Kumar

  4. Department of Chemistry, University of Perugia, Via Elce di Sotto, 8, P.O. Box, I-06123, Perugia, Italy

    Antonio Laganà

  5. Institute of High Performance Computing, IHCP, 1 Science Park Road, 01-01 The Capricorn, Singapore Science Park II, 117528, Singapore

    Heow Pueh Lee

  6. School of Computing, Soongsil University, Seoul, Korea

    Youngsong Mun

  7. Clayton School of IT, Monash University, 3800, Clayton, Australia

    David Taniar

  8. OptimaNumerics Ltd, P.O. Box, Belfast, United Kingdom

    Chih Jeng Kenneth Tan

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© 2005 Springer-Verlag Berlin Heidelberg

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Corradini, F., Merelli, E., Vita, M. (2005). A Multi-agent System for Modelling Carbohydrate Oxidation in Cell. In: Gervasi, O., et al. Computational Science and Its Applications – ICCSA 2005. ICCSA 2005. Lecture Notes in Computer Science, vol 3481. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11424826_134

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  • DOI: https://doi.org/10.1007/11424826_134

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-25861-2

  • Online ISBN: 978-3-540-32044-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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