ZNF687

ZNF687
Identifikatori
Aliasi	ZNF687
Vanjski ID-jevi	OMIM: 610568 MGI: 1925516 HomoloGene: 10827 GeneCards: ZNF687
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	151,292,176 bp
Lokacija gena (miš)
Hrom.	Hromosom 3 (miš)
Kraj	95,015,448 bp
Ontologija gena
Molekularna funkcija	• vezivanje iona metala; • vezivanje sa DNK; • GO:0001948, GO:0016582 vezivanje za proteine; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• jedro; • citoplazma; • nukleoplazma; • citosol;
Biološki proces	• GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	57592
	78266
	ENSG00000143373
	ENSMUSG00000019338
	Q8N1G0
	Q9D2D7
	NM_001304763; NM_001304764; NM_020832
	NM_030074; NM_001357863
	NP_001291692; NP_001291693; NP_065883
	NP_084350; NP_001344792
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein cinkovog prsta 687 je cinkov prst koji je kod ljudi kodiran genom ZNF687 sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 1 237 aminokiselina, a molekulska težina 129.529 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MGDMKTPDFD	DLLAAFDIPD	IDANEAIHSG	PEENEGPGGP	GKPEPGVGSE
SEDTAAASAG	DGPGVPAQAS	DHGLPPPDIS	VVSVIVKNTV	CPEQSEALAG
GSAGDGAQAA	GVTKEGPVGP	HRMQNGFGSP	EPSLPGTPHS	PAPPSGGTWK
EKGMEGKTPL	DLFAHFGPEP	GDHSDPLPPS	APSPTREGAL	TPPPFPSSFE
LAQENGPGMQ	PPVSSPPLGA	LKQESCSPHH	PQVLAQQGSG	SSPKATDIPA
SASPPPVAGV	PFFKQSPGHQ	SPLASPKVPV	CQPLKEEDDD	EGPVDKSSPG
SPQSPSSGAE	AADEDSNDSP	ASSSSRPLKV	RIKTIKTSCG	NITRTVTQVP
SDPDPPAPLA	EGAFLAEASL	LKLSPATPTS	EGPKVVSVQL	GDGTRLKGTV
LPVATIQNAS	TAMLMAASVA	RKAVVLPGGT	ATSPKMIAKN	VLGLVPQALP
KADGRAGLGT	GGQKVNGASV	VMVQPSKTAT	GPSTGGGTVI	SRTQSSLVEA
FNKILNSKNL	LPAYRPNLSP	PAEAGLALPP	TGYRCLECGD	AFSLEKSLAR
HYDRRSMRIE	VTCNHCARRL	VFFNKCSLLL	HAREHKDKGL	VMQCSHLVMR
PVALDQMVGQ	PDITPLLPVA	VPPVSGPLAL	PALGKGEGAI	TSSAITTVAA
EAPVLPLSTE	PPAAPATSAY	TCFRCLECKE	QCRDKAGMAA	HFQQLGPPAP
GATSNVCPTC	PMMLPNRCSF	SAHQRMHKNR	PPHVCPECGG	NFLQANFQTH
LREACLHVSR	RVGYRCPSCS	VVFGGVNSIK	SHIQTSHCEV	FHKCPICPMA
FKSGPSAHAH	LYSQHPSFQT	QQAKLIYKCA	MCDTVFTHKP	LLSSHFDQHL
LPQRVSVFKC	PSCPLLFAQK	RTMLEHLKNT	HQSGRLEETA	GKGAGGALLT
PKTEPEELAV	SQGGAAPATE	ESSSSSEEEE	VPSSPEPPRP	AKRPRRELGS
KGLKGGGGGP	GGWTCGLCHS	WFPERDEYVA	HMKKEHGKSV	KKFPCRLCER
SFCSAPSLRR	HVRVNHEGIK	RVYPCRYCTE	GKRTFSSRLI	LEKHVQVRHG
LQLGAQSPGR	GTTLARGSSA	RAQGPGRKRR	QSSDSCSEEP	DSTTPPAKSP
RGGPGSGGHG	PLRYRSSSST	EQSLMMGLRV	EDGAQQCLDC	GLCFASPGSL
SRHRFISHKK	RRGVGKASAL	GLGDGEEEAP	PSRSDPDGGD	SPLPASGGPL
TCKVCGKSCD	SPLNLKTHFR	THGMAFIRAR	QGAVGDN

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143373 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000019338 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.
^ "Entrez Gene: ZNF687 zinc finger protein 687".
^ "UniProt, Q8N1G0" (jezik: en.). Pristupljeno 8. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143373 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000019338 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10718198-5] Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. doi:10.1093/dnares/7.1.65. PMID 10718198.

[entrez-6] "Entrez Gene: ZNF687 zinc finger protein 687".

[UniProt-7] "UniProt, Q8N1G0" (jezik: en.). Pristupljeno 8. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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