ZNF648

ZNF648
Identifikatori
Aliasi	ZNF648
Vanjski ID-jevi	MGI: 2685049 HomoloGene: 18996 GeneCards: ZNF648
Lokacija gena (čovjek)
Hrom.	Hromosom 1 (čovjek)
Kraj	182,061,712 bp
Lokacija gena (miš)
Hrom.	Hromosom 1 (miš)
Kraj	154,081,435 bp
Ontologija gena
Molekularna funkcija	• vezivanje sa DNK; • vezivanje iona metala; • nucleic acid binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity;
Ćelijska komponenta	• jedro;
Biološki proces	• GO:0009373 regulation of transcription, DNA-templated; • transcription, DNA-templated; • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II;
	Izvori:Amigo / QuickGO
Ortolozi
	127665
	100503355
	ENSG00000179930
	ENSMUSG00000066797
	Q5T619
	D3Z0W3
	NM_001009992
	NM_001204908
	NP_001009992
	NP_001191837
	Wikipodaci
Pogledaj/uredi – čovjek	Pogledaj/uredi – miš

Protein cinkovog prsta 436 jest protein koji je kod ljudi kodiran genom ZNF436 sa hromosoma 1.^[5]^[6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 470 aminokiselina, a molekulska težina 54.277 Da.^[7]

C: Cistein

D: Asparaginska kiselina

E: Glutaminska kiselina

F: Fenilalanin

G: Glicin

H: Histidin

I: Izoleucin

K: Lizin

L: Leucin

M: Metionin

N: Asparagin

P: Prolin

Q: Glutamin

R: Arginin

S: Serin

T: Treonin

V: Valin

W: Triptofan

Y: Tirozin

10	20	30	40	50
MAATLLMAGS	QAPVTFEDMA	MYLTREEWRP	LDAAQRDLYR	DVMQENYGNV
VSLDFEIRSE	NEVNPKQEIS	EDVQFGTTSE	RPAENAEENP	ESEEGFESGD
RSERQWGDLT	AEEWVSYPLQ	PVTDLLVHKE	VHTGIRYHIC	SHCGKAFSQI
SDLNRHQKTH	TGDRPYKCYE	CGKGFSRSSH	LIQHQRTHTG	ERPYDCNECG
KSFGRSSHLI	QHQTIHTGEK	PHKCNECGKS	FCRLSHLIQH	QRTHSGEKPY
ECEECGKSFS	RSSHLAQHQR	THTGEKPYEC	NECGRGFSER	SDLIKHYRVH
TGERPYKCDE	CGKNFSQNSD	LVRHRRAHTG	EKPYHCNECG	ENFSRISHLV
QHQRTHTGEK	PYECNACGKS	FSRSSHLITH	QKIHTGEKPY	ECNECWRSFG
ERSDLIKHQR	THTGEKPYEC	VQCGKGFTQS	SNLITHQRVH	TGEKPYECTE
CEKSFSRSSA	LIKHKRVHTD

Također pogledajte

ZNF692

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000179930 - Ensembl, maj 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000066797 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.
^ "Entrez Gene: ZNF436 zinc finger protein 436".
^ "UniProt, Q9C0F3" (jezik: en.). Pristupljeno 8. 12. 2021.CS1 održavanje: nepoznati jezik (link)

Dopunska literatura

Li Y, Du X, Li F, et al. (2007). "A novel zinc-finger protein ZNF436 suppresses transcriptional activities of AP-1 and SRE". Mol. Biol. Rep. 33 (4): 287–94. doi:10.1007/s11033-006-9019-5. PMID 17089209. S2CID 13591444.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bray P, Lichter P, Thiesen HJ, et al. (1991). "Characterization and mapping of human genes encoding zinc finger proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (21): 9563–7. Bibcode:1991PNAS...88.9563B. doi:10.1073/pnas.88.21.9563. PMC 52758. PMID 1946370.
Lichter P, Bray P, Ried T, et al. (1992). "Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes". Genomics. 13 (4): 999–1007. doi:10.1016/0888-7543(92)90013-I. PMID 1505991.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000179930 - Ensembl, maj 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000066797 - Ensembl, maj 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11214970-5] Nagase T, Kikuno R, Hattori A, Kondo Y, Okumura K, Ohara O (Feb 2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (6): 347–55. doi:10.1093/dnares/7.6.347. PMID 11214970.

[entrez-6] "Entrez Gene: ZNF436 zinc finger protein 436".

[UniProt-7] "UniProt, Q9C0F3" (jezik: en.). Pristupljeno 8. 12. 2021.CS1 održavanje: nepoznati jezik (link)

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