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Kornifin-A jest protein koji je kod ljudi kodiran genom SPRR1A sa hromosoma 1.[5][6]

SPRR1A
Identifikatori
AliasiSPRR1A
Vanjski ID-jeviOMIM: 182265 MGI: 106660 HomoloGene: 105698 GeneCards: SPRR1A
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za SPRR1A
Genomska lokacija za SPRR1A
Bend1q21.3Početak152,984,081 bp[1]
Kraj152,985,814 bp[1]
Lokacija gena (miš)
Hromosom 3 (miš)
Hrom.Hromosom 3 (miš)[2]
Hromosom 3 (miš)
Genomska lokacija za SPRR1A
Genomska lokacija za SPRR1A
Bend3 F1|3 40.14 cMPočetak92,391,259 bp[2]
Kraj92,393,202 bp[2]
Obrazac RNK ekspresije


Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija protein-macromolecule adaptor activity
GO:0001948, GO:0016582 vezivanje za proteine
structural molecule activity
structural constituent of skin epidermis
Ćelijska komponenta citoplazma
cornified envelope
citosol
Biološki proces GO:0051357, GO:0051358, GO:0051359 peptide cross-linking
keratinization
keratinocyte differentiation
epidermis development
cornification
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_005987
NM_001199828

NM_009264

RefSeq (bjelančevina)

NP_001186757
NP_005978

NP_033290

Lokacija (UCSC)Chr 1: 152.98 – 152.99 MbChr 3: 92.39 – 92.39 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Aminokiselinska sekvenca

uredi

Dužina polipeptidnog lanca je 89 aminokiselina, a molekulska težina 9.877 Da.[7]

1020304050
MNSQQQKQPCTPPPQPQQQQVKQPCQPPPQEPCIPKTKEPCHPKVPEPCH
PKVPEPCQPKVPEPCQPKVPEPCPSTVTPAPAQQKTKQK

Reference

uredi
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000169474 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000050359 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (juni 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.
  6. ^ "Entrez Gene: SPRR1A small proline-rich protein 1A".
  7. ^ "UniProt, P35321" (jezik: engleski). Pristupljeno 19. 12. 2021.

Dopunska literatura

uredi