By Rachel Leeson
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Prime Editing: Precise and Flexible CRISPR Editing Over 75,000 pathogenic genetic variants have been identified in humans and cataloged in the ClinVar database. Previously developed genome editing methods using nucleases and base editors have the potential to correct only a ...
Injections in mice are a day-to-day task for many labs. Deciding which type of injection to use depends on a number of factors. You have to weigh the pros and cons of various methods and choose what is best for you — and the mice. While not an exhaustive list, these can include ...
It’s a very thankful time of year for those of us at Addgene! And we can’t think of any better way to start off our holiday season than by thanking the twelve guest bloggers and subject matter experts who have contributed to our blog in 2024.
When Addgene opened in 2004, we focused on creating a repository that made it easy to share plasmids, both for people depositing plasmids and for people requesting them. Prior to this, many plasmids were available, but they often weren’t easily accessible, due to a wide range of ...
Every few months, we highlight some of the new plasmids, antibodies, and viral preps in the repository through our Hot Plasmids articles.
Thinking about using antibody-based applications in your experiment...but not sure where to start or what your options are? Addgene's latest animation is here to help!
You’ve probably heard that only 2% of our genome is made of protein-coding genes, and you might be wondering what the rest of our genome could possibly be made up of. The answer is… drum roll please… non-coding RNAs! You probably didn’t see that coming, right? Non-coding RNAs ...