ZINC20

Welcome to ZINC, a free database of commercially-available compounds for virtual screening. ZINC contains over 230 million purchasable compounds in ready-to-dock, 3D formats. ZINC also contains over 750 million purchasable compounds you can search for analogs in under a minute.

ZINC is provided by the Irwin and Shoichet Laboratories in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF). We thank NIGMS for financial support (GM71896).

To cite ZINC, please reference: Irwin, Tang, Young, Dandarchuluun, Wong, Khurelbaatar, Moroz, Mayfield, Sayle, J. Chem. Inf. Model 2020, in press. https://pubs.acs.org/doi/10.1021/acs.jcim.0c00675. You may also wish to cite our previous papers: Sterling and Irwin, J. Chem. Inf. Model, 2015 http://pubs.acs.org/doi/abs/10.1021/acs.jcim.5b00559. Irwin, Sterling, Mysinger, Bolstad and Coleman, J. Chem. Inf. Model, 2012 DOI: 10.1021/ci3001277 or Irwin and Shoichet, J. Chem. Inf. Model. 2005;45(1):177-82 PDF, DOI.