Cooperative tumorigenic effects of germline mutations in Rb and p53 (Q72781894)

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29 October 2019

title

Cooperative tumorigenic effects of germline mutations in Rb and p53 (English)

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29 October 2019

Williams BO

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29 October 2019

Remington L

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29 October 2019

Albert DM

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29 October 2019

Mukai S

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29 October 2019

Bronson RT

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29 October 2019

Jacks T

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29 October 2019

publication date

1 August 1994

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29 October 2019

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29 October 2019

volume

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29 October 2019

issue

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29 October 2019

page(s)

480-484

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Antioncogenes and human cancer

29 October 2019

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p53 functions as a cell cycle control protein in osteosarcomas

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Genetic basis for p53 overexpression in human breast cancer

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Integration of cell cycle control with transcriptional regulation by the retinoblastoma protein

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

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7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

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7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Thymocyte apoptosis induced by p53-dependent and independent pathways.

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7 January 2021

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

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7 January 2021

Effects of an Rb mutation in the mouse

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Requirement for a functional Rb-1 gene in murine development

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7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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7 January 2021

Tumor spectrum analysis in p53-mutant mice

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7 January 2021

Cancer. p53, guardian of the genome

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7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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7 January 2021

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

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7 January 2021

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

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7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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7 January 2021

Retinoblastoma in transgenic mice

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7 January 2021

Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter

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7 January 2021

The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

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7 January 2021

An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

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7 January 2021

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7 January 2021

Retinoblastoma and intracranial malignancy

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/NG0894-480

1 reference

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29 October 2019

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