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Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase (Q40723397)

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scientific article published on 20 June 2002

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English	Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase	scientific article published on 20 June 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Regulation of signaling in B cells through the phosphorylation of Syk on linker region tyrosines. A mechanism for negative signaling by the Lyn tyrosine kinase (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Julie J Hong

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Thomas M Yankee

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Marietta L Harrison

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Robert L Geahlen

4

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

0 references

publication date

20 June 2002

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

23 September 2017

277

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

35

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

31703-31714

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PtdIns-3,4,5-P3: a regulatory nexus between tyrosine kinases and sustained calcium signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Regulation of the phospholipase C-gamma2 pathway in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Proximal protein tyrosine kinases in immunoreceptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Regulation of B-cell activation and differentiation by the phosphatidylinositol 3-kinase and phospholipase Cgamma pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Syk tyrosine kinase required for mouse viability and B-cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

SYK is upstream of phosphoinositide 3-kinase in B cell receptor signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

BLNK: a central linker protein in B cell activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

BLNK required for coupling Syk to PLC gamma 2 and Rac1-JNK in B cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Inhibition of the B cell by CD22: a requirement for Lyn

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

A Double-Edged Kinase Lyn: A Positive and Negative Regulator for Antigen Receptor–mediated Signals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Phospholipase C-gamma1 interacts with conserved phosphotyrosyl residues in the linker region of Syk and is a substrate for Syk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Syk activation and dissociation from the B-cell antigen receptor is mediated by phosphorylation of tyrosine 130

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Xid-like phenotypes: a B cell signalosome takes shape

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Identification of the major sites of autophosphorylation of the murine protein-tyrosine kinase Syk

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Differential signaling by lymphocyte antigen receptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Positive versus negative signaling by lymphocyte antigen receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Differential activation of transcription factors induced by Ca2+ response amplitude and duration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Persistent calcium elevation correlates with the induction of surface immunoglobulin-mediated B cell DNA synthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Abnormal development and function of B lymphocytes in mice deficient for the signaling adaptor protein SLP-65

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Requirement for B cell linker protein (BLNK) in B cell development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

BLNK mediates Syk-dependent Btk activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Defective B cell development and function in Btk-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Impaired expansion of mouse B cell progenitors lacking Btk.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Co-receptors on B lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

CD19 amplification of B lymphocyte Ca2+ responses: a role for Lyn sequestration in extinguishing negative regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

syk kinase activation by a src kinase-initiated activation loop phosphorylation chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201362200

21 January 2018

Identifiers

10.1074/JBC.M201362200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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