Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing (Q33887127)

29 July 2017

title

Identification of a human protein that recognizes the 3' splice site during the second step of pre-mRNA splicing (English)

1 reference

29 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

10 November 2024

S. Wu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

10 November 2024

M. R. Green

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

10 November 2024

language of work or name

English

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publication date

1 July 1997

1 reference

29 July 2017

16 July 1997

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9250686

full work available at URL

10 November 2024

https://europepmc.org/articles/pmc1170068?pdf=render

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

https://europepmc.org/articles/PMC1170068

10 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

https://europepmc.org/articles/PMC1170068?pdf=render

10 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

https://doi.org/10.1093/emboj/16.14.4421

10 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9250686

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1093%2Femboj%2F16.14.4421

10 November 2024

1 reference

Crossref

DOI

10.1093/EMBOJ/16.14.4421

https://api.crossref.org/works/10.1093/EMBOJ/16.14.4421

https://onlinelibrary.wiley.com/doi/full/10.1093/emboj/16.14.4421

10 November 2024

1 reference

Crossref

DOI

10.1093/EMBOJ/16.14.4421

https://api.crossref.org/works/10.1093/EMBOJ/16.14.4421

10 November 2024

1 reference

29 July 2017

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29 July 2017

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29 July 2017

page(s)

4421-4432

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The structure and function of proteins involved in mammalian pre-mRNA splicing

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Identification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

The second catalytic step of pre-mRNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A 69-kD protein that associates reversibly with the Sm core domain of several spliceosomal snRNP species.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Mutations in U6 snRNA that alter splice site specificity: implications for the active site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Disruption of base pairing between the 5' splice site and the 5' end of U1 snRNA is required for spliceosome assembly

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Interaction of the yeast splicing factor PRP8 with substrate RNA during both steps of splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Extensive interactions of PRP8 protein with the 5' and 3' splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Dynamic RNA-RNA interactions in the spliceosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Sequential recognition of the pre-mRNA branch point by U2AF65 and a novel spliceosome-associated 28-kDa protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Members of a family of proteins (the RD family) detected by a U1 70K monoclonal antibody are present in spliceosomal complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A compensatory base change in U1 snRNA suppresses a 5' splice site mutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Identification of a functional mammalian spliceosome containing unspliced pre-mRNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A protein that specifically recognizes the 3' splice site of mammalian pre-mRNA introns is associated with a small nuclear ribonucleoprotein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Gel electrophoretic isolation of splicing complexes containing U1 small nuclear ribonucleoprotein particles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Scanning from an independently specified branch point defines the 3' splice site of mammalian introns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A compensatory base change in human U2 snRNA can suppress a branch site mutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Exon mutations uncouple 5' splice site selection from U1 snRNA pairing.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

An essential splicing factor, SLU7, mediates 3' splice site choice in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Association of U6 snRNA with the 5'-splice site region of pre-mRNA in the spliceosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

A novel role for a U5 snRNP protein in 3' splice site selection.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1170068

Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro

29 October 2018

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12 December 2020

Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA

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12 December 2020

A mutational analysis of spliceosome assembly: evidence for splice site collaboration during spliceosome formation

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12 December 2020

A factor, U2AF, is required for U2 snRNP binding and splicing complex assembly

1 reference

12 December 2020

Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.

1 reference

12 December 2020

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns

1 reference

12 December 2020

The organization of 3' splice-site sequences in mammalian introns

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12 December 2020

The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors

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12 December 2020

Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing

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12 December 2020

Interaction of mammalian splicing factor SF3a with U2 snRNP and relation of its 60-kD subunit to yeast PRP9

1 reference

12 December 2020

Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing

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12 December 2020

The U5 and U6 small nuclear RNAs as active site components of the spliceosome

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12 December 2020

Involvement of U6 snRNA in 5' splice site selection

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/16.14.4421

1 reference

29 July 2017

1 reference

29 July 2017

1 reference