The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. (Q33852211)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

The telomerase reverse transcriptase regulates chromatin state and DNA damage responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

William C Hahn

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Kenkichi Masutomi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Jennifer L Currier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Zuzana Tothova

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Judith B Manola

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Shridar Ganesan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Peter M Lansdorp

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Kathleen Collins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

language of work or name

English

0 references

publication date

31 May 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

12 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

page(s)

8222-8227

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

12 January 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1149439/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Homologous recombination generates T-loop-sized deletions at human telomeres

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Functional links between telomeres and proteins of the DNA-damage response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Regulation of heterochromatin by histone methylation and small RNAs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

A DNA damage checkpoint response in telomere-initiated senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Human telomerase reverse transcriptase motifs required for elongation of a telomeric substrate.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Evolving views of telomerase and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

DNA methylation in animal development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Cellular senescence as a tumor-protection mechanism: the essential role of counting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Chromosome healing in mouse embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Extension of life-span by introduction of telomerase into normal human cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Unusual chromatin in human telomeres

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Healing of broken human chromosomes by the addition of telomeric repeats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Telomerase maintains telomere structure in normal human cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Inhibition of telomerase limits the growth of human cancer cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1149439

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

29 October 2018

1 reference

12 December 2020

New telomeres in yeast are initiated with a highly selected subset of TG1-3 repeats

1 reference

12 December 2020

Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice

1 reference

12 December 2020

Short telomeres on human chromosome 17p

1 reference

12 December 2020

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

12 December 2020

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

12 December 2020

Erosion of the telomeric single-strand overhang at replicative senescence

1 reference

12 December 2020

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0503095102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

15928077

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15928077%20AND%20SRC:MED&resulttype=core&format=json