Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia (Q38287709)

1 September 2017

title

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia (English)

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1 September 2017

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Eric S Lander

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1 September 2017

Todd R Golub

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1 September 2017

Adolfo A Ferrando

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1 September 2017

Donna S Neuberg

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1 September 2017

Jane Staunton

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1 September 2017

Mignon L Loh

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1 September 2017

Christine Huard

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1 September 2017

Susana C Raimondi

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1 September 2017

Fred G Behm

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1 September 2017

Ching Hon Pui

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1 September 2017

James R Downing

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1 September 2017

D Gary Gilliland

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1 September 2017

A Thomas Look

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1 September 2017

publication date

1 February 2002

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1 September 2017

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1 September 2017

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1 September 2017

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1 September 2017

page(s)

75-87

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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

1 September 2017

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Chromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript

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Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias

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A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

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The rhombotin family of cysteine-rich LIM-domain oncogenes: distinct members are involved in T-cell translocations to human chromosomes 11p15 and 11p13

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Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia

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Hemizygous p16(INK4A) deletion in pediatric acute lymphoblastic leukemia predicts independent risk of relapse

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The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein

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Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice

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Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia–lymphoma cells

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7 January 2021

Early thymocyte development is regulated by modulation of E2A protein activity

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Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma

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Precursors of CD3+CD4+CD8+ cells in the human thymus are defined by expression of CD34. Delineation of early events in human thymic development

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Adaptor FYB (Fyn-binding protein) regulates integrin-mediated adhesion and mediator release: differential involvement of the FYB SH3 domain

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

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Segmental and developmental regulation of a presumptive T-cell oncogene in the central nervous system

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Positive Regulation of T Cell Activation and Integrin Adhesion by the Adapter Fyb/Slap

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7 January 2021

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

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7 January 2021

SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression

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7 January 2021

Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells

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7 January 2021

HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint

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7 January 2021

Tal-1 induces T cell acute lymphoblastic leukemia accelerated by casein kinase IIalpha.

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HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

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Oncogenic Transcription Factors in the Human Acute Leukemias

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7 January 2021

Bclx regulates the survival of double-positive thymocytes

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7 January 2021

The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein

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7 January 2021

Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma

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7 January 2021

lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif

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7 January 2021

Prevalence and prognostic significance of Flt3 internal tandem duplication in pediatric acute myeloid leukemia

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7 January 2021

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Molecular and cellular events in early thymocyte development

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7 January 2021

Childhood acute lymphoblastic leukemia with the MLL-ENL fusion and t(11;19)(q23;p13.3) translocation

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7 January 2021

Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest

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7 January 2021

Rnx deficiency results in congenital central hypoventilation

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7 January 2021

Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.

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7 January 2021

Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation

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7 January 2021

Within the hemopoietic system, LAR phosphatase is a T cell lineage-specific adhesion receptor-like protein whose phosphatase activity appears dispensable for T cell development, repertoire selection and function

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7 January 2021

Expression of the Bcl-2 family member A1 is developmentally regulated in T cells

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7 January 2021

A Positive Role for Thymus‐Derived Steroids in Formation of the T‐Cell Repertoire

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7 January 2021

The LIM protein RBTN2 and the basic helix-loop-helix protein TAL1 are present in a complex in erythroid cells

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7 January 2021

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

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7 January 2021

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

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7 January 2021

The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene

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7 January 2021

Genome-wide expression monitoring in Saccharomyces cerevisiae

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7 January 2021

TAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemia

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7 January 2021

High Incidence of T-Cell Tumors in E2A-Null Mice and E2A/Id1 Double-Knockout Mice

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7 January 2021

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

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7 January 2021

10.1016/S1535-6108(02)00018-1

Identifiers

DOI

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1 September 2017

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