E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner (Q28972449)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

title

E-cadherin suppresses cellular transformation by inhibiting beta-catenin signaling in an adhesion-independent manner (English)

1 reference

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8 November 2019

1 reference

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8 November 2019

E Wong

1 reference

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8 November 2019

B M Gumbiner

series ordinal

1 reference

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8 November 2019

language of work or name

English

0 references

publication date

1 May 2001

1 reference

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8 November 2019

published in

Journal of Cell Biology

2 references

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8 November 2019

volume

153

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

2 references

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

page(s)

1049-1060

2 references

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20 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

A novel beta-catenin-binding protein inhibits beta-catenin-dependent Tcf activation and axis formation

8 November 2019

cites work

1 reference

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Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein

20 March 2017

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Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion

20 March 2017

1 reference

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

20 March 2017

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The C-terminal transactivation domain of beta-catenin is necessary and sufficient for signaling by the LEF-1/beta-catenin complex in Xenopus laevis

20 March 2017

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20 March 2017

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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

20 March 2017

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

20 March 2017

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

20 March 2017

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Functional interaction of beta-catenin with the transcription factor LEF-1

20 March 2017

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

20 March 2017

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

20 March 2017

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The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex

20 March 2017

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

20 March 2017

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Mechanisms of Wnt signaling in development

20 March 2017

1 reference

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A causal role for E-cadherin in the transition from adenoma to carcinoma

7 April 2017

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Morphogenetic roles of classic cadherins

7 April 2017

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7 April 2017

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Tumor suppressors: linking cell polarity and growth control.

3 June 2018

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Biochemical interactions in the wnt pathway

3 June 2018

1 reference

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A comparative evaluation of various invasion assays testing colon carcinoma cell lines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

A cell-free assay system for beta-catenin signaling that recapitulates direct inductive events in the early xenopus laevis embryo

3 June 2018

1 reference

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Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

3 June 2018

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The Wnt/Wg signal transducer beta-catenin controls fibronectin expression

3 June 2018

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The metalloproteinase matrilysin is a target of beta-catenin transactivation in intestinal tumors

3 June 2018

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beta-catenin signalling modulates proliferative potential of human epidermal keratinocytes independently of intercellular adhesion

3 June 2018

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The oncogenic activation of beta-catenin

3 June 2018

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E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)

3 June 2018

1 reference

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Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

3 June 2018

1 reference

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Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

3 June 2018

1 reference

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Wnt-1 induces growth, cytosolic beta-catenin, and Tcf/Lef transcriptional activation in Rat-1 fibroblasts

3 June 2018

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E-cadherin germline mutations in familial gastric cancer.

3 June 2018

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E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Cell contact-dependent signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Lateral dimerization is required for the homophilic binding activity of C-cadherin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Armadillo is required for adherens junction assembly, cell polarity, and morphogenesis during Drosophila embryogenesis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Increased cell-substratum adhesion, and decreased gelatinase secretion and cell growth, induced by E-cadherin transfection of human colon carcinoma cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Induction of a secondary body axis in Xenopus by antibodies to beta-catenin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

How and when do tumor cells metastasize?

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Cadherins in cancer: implications for invasion and metastasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line

3 June 2018

1 reference

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The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules

3 June 2018

1 reference

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Disruption of gastrulation movements in Xenopus by a dominant-negative mutant for C-cadherin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

A beta-catenin/engrailed chimera selectively suppresses Wnt signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Regulation of E-cadherin/Catenin association by tyrosine phosphorylation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

Contribution of cadherins to directional cell migration and histogenesis in Xenopus embryos.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2174337

A mode of regulation of beta-catenin signaling activity in Xenopus embryos independent of its levels

26 November 2018

1 reference

12 December 2020

Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain

1 reference

12 December 2020

A short core region of E-cadherin is essential for catenin binding and is highly phosphorylated

1 reference

12 December 2020

Catenin-dependent and -independent Functions of Vascular Endothelial Cadherin

1 reference

12 December 2020

Forced expression of E-cadherin in the mouse intestinal epithelium slows cell migration and provides evidence for nonautonomous regulation of cell fate in a self-renewing system

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.153.5.1049

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2174337

3 references

20 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pmc&retmode=json&id=2174337

8 November 2019

PubMed publication ID

3 references

20 March 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11381089%20AND%20SRC:MED&resulttype=core&format=json