Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase (Q28202311)

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scientific article (publication date: 11 July 2003)

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English	Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase	scientific article (publication date: 11 July 2003)

Statements

instance of

scholarly article

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title

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase (English)

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author

Avram Hershko

series ordinal

6

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Michele Pagano

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5

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author name string

Gil Bornstein

series ordinal

1

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Joanna Bloom

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2

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Danielle Sitry-Shevah

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3

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Keiko Nakayama

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4

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language of work or name

English

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publication date

11 July 2003

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published in

Journal of Biological Chemistry

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volume

278

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issue

28

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page(s)

25752-7

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cites work

CDK inhibitors: positive and negative regulators of G1-phase progression

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

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11 October 2022

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Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

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11 October 2022

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A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

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11 October 2022

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Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

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11 October 2022

reference URL

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Growth inhibition by CDK-cyclin and PCNA binding domains of p21 occurs by distinct mechanisms and is regulated by ubiquitin-proteasome pathway

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11 October 2022

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A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome

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11 October 2022

reference URL

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

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11 October 2022

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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation

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11 October 2022

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Three different binding sites of Cks1 are required for p27-ubiquitin ligation

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Cdk inhibitors in development and cancer

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Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway

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Proteolysis and the cell cycle: with this RING I do thee destroy

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A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Functional receptors for vasoactive intestinal peptide in cultured vascular smooth muscle cells from rat aorta

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11 October 2022

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Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Cyclin E-CDK2 is a regulator of p27Kip1.

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

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COCI

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11 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Inhibitors of mammalian G1 cyclin-dependent kinases

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

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COCI

retrieved

11 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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COCI

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11 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

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COCI

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11 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2).

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

SCF and Cullin/Ring H2-based ubiquitin ligases

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination

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COCI

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11 October 2022

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https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein.

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stated in

COCI

retrieved

11 October 2022

reference URL

https://opencitations.net/index/coci/api/v1/references/10.1074/JBC.M301774200

Identifiers

DOI

10.1074/JBC.M301774200

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3705728

OpenCitations bibliographic resource ID

3705728

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3705728

PubMed publication ID

12730199

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stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3705728

ResearchGate publication ID

10775480

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