Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities (Q24303505)

Ubiquitin specific peptidase 44

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Ubiquitin conjugating enzyme E2 C

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negative regulation of ubiquitin protein ligase activity

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protein ubiquitination

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Michael Rape

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Peter K Sorger

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Gregory J Hannon

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Robert McDonald

object named as

E Robert McDonald

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author name string

Frank Stegmeier

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Viji M Draviam

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Mathew E Sowa

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Xiaolu L Ang

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Mamie Z Li

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Marc W Kirschner

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J Wade Harper

Genetic instabilities in human cancers

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language of work or name

English

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publication date

19 April 2007

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published in

Nature

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volume

446

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issue

7138

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page(s)

876-81

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cites work

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7 January 2021

Chromosome segregation and genomic stability

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On the road to cancer: aneuploidy and the mitotic checkpoint

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The anaphase promoting complex/cyclosome: a machine designed to destroy

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The spindle checkpoint: structural insights into dynamic signalling

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The spindle checkpoint, aneuploidy, and cancer

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How do so few control so many?

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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

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Feedback control of mitosis in budding yeast

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The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpoint

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Rod-Zw10-Zwilch: a key player in the spindle checkpoint

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Identification of a MAD2-binding protein, CMT2, and its role in mitosis

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Conformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpoint

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7 January 2021

Determinants of conformational dimerization of Mad2 and its inhibition by p31comet

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ZW10 links mitotic checkpoint signaling to the structural kinetochore.

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7 January 2021

Ubiquitination by the anaphase-promoting complex drives spindle checkpoint inactivation

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7 January 2021

Second-generation shRNA libraries covering the mouse and human genomes

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Timing and checkpoints in the regulation of mitotic progression

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7 January 2021

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

1 reference

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7 January 2021

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

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7 January 2021

Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry.

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7 January 2021

The processivity of multiubiquitination by the APC determines the order of substrate degradation.

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7 January 2021

Bistability in cell signaling: How to make continuous processes discontinuous, and reversible processes irreversible

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7 January 2021

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

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Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C

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7 January 2021

Closing mitosis: the functions of the Cdc14 phosphatase and its regulation

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