Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene (Q24301993)

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English	Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene	scientific article

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instance of

scholarly article

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title

Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene (English)

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main subject

Ig heavy chain V-I region 5

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stated in

GOA release 2020-03-11

Ig kappa chain V-ID region 16

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stated in

GOA release 2020-03-11

immune response

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stated in

GOA release 2020-03-11

author name string

D L Bentley

series ordinal

1

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T H Rabbitts

series ordinal

2

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language of work or name

English

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publication date

25 December 1980

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published in

Nature

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volume

288

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issue

5792

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page(s)

730-3

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cites work

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A complete immunoglobulin gene is created by somatic recombination

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A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

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Sequences at the somatic recombination sites of immunoglobulin light-chain genes

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Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene

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Contribution of immunoglobulin heavy-chain variable-region genes to antibody diversity

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An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

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Redundant genes

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Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries

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Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

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Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

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Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

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7 Synthetic adaptors for cloning DNA

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Promoter sequences of eukaryotic protein-coding genes

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Identifiers

DOI

10.1038/288730A0

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Dimensions Publication ID

1052617602

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PubMed publication ID

6779204

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