Neuroscience articles from across Nature Portfolio

Neuroscience is a multidisciplinary science that is concerned with the study of the structure and function of the nervous system. It encompasses the evolution, development, cellular and molecular biology, physiology, anatomy and pharmacology of the nervous system, as well as computational, behavioural and cognitive neuroscience.

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Advances in appetite regulation by the arcuate nucleus

In 2024, new insights identified a cluster of leptin-targeted neurons and integrative networks that link sensory inputs (heat and food perception) with feeding centres and peripheral systems. Key findings revealed hypothalamic site-specific adaptive mechanisms, in which nutritional state-dependent remodelling of extracellular compounds and neuropeptide transmission calibrate appetite via the arcuate nucleus.
- Cristina Garcia-Caceres
News & Views13 Dec 2024 Nature Reviews Endocrinology
P: 1-2
Enhancing consistency in brain imaging research for population neuroimaging

Standardized neuroimaging protocols are essential to advancing comparability and replicability. Now, a comprehensive magnetic resonance imaging acquisition and analysis protocol from the Rhineland Study provides a valuable framework for image acquisition and analysis that is suitable for both large- and small-scale neuroimaging studies.
- Ryan L. Muetzel
News & Views13 Dec 2024 Nature Protocols
P: 1-2
Motivating interest in D3 dopamine receptors

Reward signaling via dopamine is most commonly thought of as acting through neurons expressing either D1 or D2 dopamine receptors. Enriquez-Traba et al. show that neurons in the ventral striatum co-express D1 and D3 receptors, which they use to signal dissociable aspects of reward.
- Nicolas X. Tritsch
News & Views09 Dec 2024 Nature Neuroscience
P: 1-2

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Latest Research and Reviews

Reply to: Limitations in odour recognition and generalization in a neuromorphic olfactory circuit
- Roy Moyal
- Nabil Imam
- Thomas A. Cleland
Research16 Dec 2024 Nature Machine Intelligence
P: 1-3
ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice

Endocannabinoid signalling processes are implicated in body weight regulation. Here, authors used viral-genetic tools to identify the enzyme ABHD6 in postsynaptic mesoaccumbal neurons is a key determinant of body weight and reward-relevant behaviour.
- David Lau
- Stephanie Tobin
- Stephanie Fulton
ResearchOpen Access16 Dec 2024 Nature Communications
Volume: 15, P: 10652
An integrative data-driven model simulating C. elegans brain, body and environment interactions

BAAIWorm is an integrative data-driven model of C. elegans that simulates interactions between the brain, body and environment. The biophysically detailed neuronal model is capable of replicating the zigzag movement observed in this species.
- Mengdi Zhao
- Ning Wang
- Tiejun Huang
ResearchOpen Access16 Dec 2024 Nature Computational Science
P: 1-13
A critical role of action-related functional networks in Gilles de la Tourette syndrome

By leveraging diverse datasets from brain stimulation therapy for Tourette Syndrome and tic-inducing brain lesions, Baldermann et al. reveal a critical role of action-related functional networks in both the treatment and pathophysiology of tic disorders.
- Juan Carlos Baldermann
- Jan Niklas Petry-Schmelzer
- Michael T. Barbe
ResearchOpen Access16 Dec 2024 Nature Communications
Volume: 15, P: 10687
Amygdala intercalated cells form an evolutionarily conserved system orchestrating brain networks

This comprehensive review of amygdala intercalated cells (ITCs) proposes a revised model of ITCs as a highly coordinated system that integrates diverse inputs to orchestrate brain-wide networks and shape behavioral states.
- Ayla Aksoy-Aksel
- Francesco Ferraguti
- Ingrid Ehrlich
Reviews13 Dec 2024 Nature Neuroscience
P: 1-14
Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation

Using intracranial recordings in pairs of humans cooperating in interactive games, this study shows fine-grained cooperation dynamics featured by state-dependent motives and the intrabrain and interbrain profiles of high-gamma activity in the amygdala and temporoparietal junction.
- Jiaxin Wang
- Fangang Meng
- Yina Ma
Research13 Dec 2024 Nature Neuroscience
P: 1-13

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News and Comment

The neuroendocrinology of stress and the importance of a proper balance between the mineralocorticoid and glucocorticoid receptors
- Philip W. Gold
- Ma-Li Wong
Editorial16 Dec 2024 Molecular Psychiatry
Volume: 30, P: 1-3
Muscle spindle macrophages regulate motor coordination

Yan et al. report the identification of a population of muscle spindle macrophages, which regulate the muscle stretch reflex through glutamate production.
- Kirsty Minton
Research Highlights16 Dec 2024 Nature Reviews Immunology
P: 1
CASP2 biallelic truncating variants: a new case supports the link with lissencephaly/pachygyria and expands the clinical spectrum
- Ilaria Vivaldi
- Marco Imperi
- Paolo Prontera
Correspondence13 Dec 2024 European Journal of Human Genetics
P: 1-3
Advances in appetite regulation by the arcuate nucleus

In 2024, new insights identified a cluster of leptin-targeted neurons and integrative networks that link sensory inputs (heat and food perception) with feeding centres and peripheral systems. Key findings revealed hypothalamic site-specific adaptive mechanisms, in which nutritional state-dependent remodelling of extracellular compounds and neuropeptide transmission calibrate appetite via the arcuate nucleus.
- Cristina Garcia-Caceres
News & Views13 Dec 2024 Nature Reviews Endocrinology
P: 1-2
Enhancing consistency in brain imaging research for population neuroimaging

Standardized neuroimaging protocols are essential to advancing comparability and replicability. Now, a comprehensive magnetic resonance imaging acquisition and analysis protocol from the Rhineland Study provides a valuable framework for image acquisition and analysis that is suitable for both large- and small-scale neuroimaging studies.
- Ryan L. Muetzel
News & Views13 Dec 2024 Nature Protocols
P: 1-2
Motivating interest in D3 dopamine receptors

Reward signaling via dopamine is most commonly thought of as acting through neurons expressing either D1 or D2 dopamine receptors. Enriquez-Traba et al. show that neurons in the ventral striatum co-express D1 and D3 receptors, which they use to signal dissociable aspects of reward.
- Nicolas X. Tritsch
News & Views09 Dec 2024 Nature Neuroscience
P: 1-2

All News & Comment

Neuroscience articles from across Nature Portfolio

Featured

Advances in appetite regulation by the arcuate nucleus

Enhancing consistency in brain imaging research for population neuroimaging

Motivating interest in D3 dopamine receptors

Related Subjects

Latest Research and Reviews

Reply to: Limitations in odour recognition and generalization in a neuromorphic olfactory circuit

ABHD6 loss-of-function in mesoaccumbens postsynaptic but not presynaptic neurons prevents diet-induced obesity in male mice

An integrative data-driven model simulating C. elegans brain, body and environment interactions

A critical role of action-related functional networks in Gilles de la Tourette syndrome

Amygdala intercalated cells form an evolutionarily conserved system orchestrating brain networks

Simultaneous intracranial recordings of interacting brains reveal neurocognitive dynamics of human cooperation

News and Comment

The neuroendocrinology of stress and the importance of a proper balance between the mineralocorticoid and glucocorticoid receptors

Muscle spindle macrophages regulate motor coordination

CASP2 biallelic truncating variants: a new case supports the link with lissencephaly/pachygyria and expands the clinical spectrum

Advances in appetite regulation by the arcuate nucleus

Enhancing consistency in brain imaging research for population neuroimaging

Motivating interest in D3 dopamine receptors

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