150 years of Nature

A century and a half has seen momentous changes in science. But evidence and transparency are more important than ever before.

Explore the network in our interactive, animated video, and PDF downloads of our 150th anniversary cover and infographic

An analysis of the archive shows how the contributors and content have varied over the decades.

In this collection of essays published to mark Nature’s 150th anniversary, leading historians explore how the past century and a half has forged some of the defining features of today’s scientific system.

A series of News & Views articles assesses the importance and lasting impact of 10 key papers from our archive.

In this collection of day-in-the-life posts, staff at Nature explain what it’s like working for the journal.

The first issue of Nature was published in November 1869. That makes 2019 its 150^th anniversary year. This video explores the past, present and future of Nature.

We asked readers what we should focus on in the next decade. Here is what you said.

Image-making, research and visual technologies have shaped each other over the past century and a half, argues Geoffrey Belknap, marking Nature’s anniversary.

The first issue of Nature was published 150 years ago, on the 4th of November 1869. In celebration of the anniversary, we highlight some of our favourite geoscience stories from the archives.

To celebrate the 150th anniversary of Nature, we survey some highlights from the journal’s ecology and evolution archives.

To navigate the present, we must heed the lessons of history.

In the 150 years since the first issue was published, Nature has evolved alongside the research community it serves. We hope to continue to grow in the years to come.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

As part of Nature's 150th anniversary celebrations, we look back at an important moment in the history of science.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

Benjamin Thompson and Nick Howe bring you the latest science updates.

In the Nature PastCast series, we delve into the archives to tell the stories behind some of Nature’s biggest papers.

This Review describes progress in the study of human genetics, in which rapid advances in technology, foundational genomic resources and analytical tools have contributed to the understanding of the mechanisms responsible for many rare and common diseases and to preventative and therapeutic strategies for many of these conditions.

Current barriers and limitations to HIV treatments are reviewed, and suggestions for future steps to achieve an effective curative intervention are discussed.

A Review of studies into insulin resistance and hepatic gluconeogenesis associated with obesity and type 2 diabetes.

A review of drug resistance in cancer analyses each biological determinant of resistance separately and discusses existing and new therapeutic strategies to combat the problem as a whole.

Structural metals enable improved energy efficiency through their reduced mass, higher thermal stability and better mechanical properties; here, methods of improving the sustainability of structural metals, from recycling to contaminant tolerance, are described.

Processes for dismantling and recycling lithium-ion battery packs from scrap electric vehicles are outlined.

Ten pathways for the utilization of carbon dioxide are reviewed, considering their potential scale, economics and barriers to implementation.

This Perspective examines the global production ecosystem through the lenses of connectivity, diversity and feedback, and proposes measures that will increase its stability and sustainability.

Genetic strategies for improving the yield and sustainability of agricultural crops, and the resilience of crops in the face of biotic and abiotic stresses contingent on projected climate change, are evaluated.

An overview of the effects of vaccines on global morbidity and mortality, vaccine safety issues, and the hurdles involved in proceeding from vaccine discovery to successful implementation.

We need to integrate the knowledge and skills from different disciplines and from communities all over the world to enable effective responses to future epidemics.

The authors discuss the potential for sex and gender analysis to foster scientific discovery, improve experimental efficiency and enable social equality.

The processes that control the movement of carbon from microfossils on the seafloor to erupting volcanoes and deep diamonds, in a cycle driven by plate tectonics, are reviewed.

HuBMAP supports technology development, data acquisition, and spatial analyses to generate comprehensive molecular and cellular three-dimensional tissue maps.

A Review of advances in memory-editing techniques in humans suggests that these techniques are advancing beyond science fiction and could hold promise for translation into clinical practice.

The authors review recent advances and current debates in epigenetics, including how epigenetic mechanisms interact with genetic variation, ageing, disease and the environment.

A method of tracking changes in estimates of the remaining carbon budget over time should help to reconcile differences between these estimates and clarify their usefulness for setting emission reduction targets.

The milestones that mark the advances in ageing research, the medical, commercial and societal implications of ageing and the different ageing pathways and processes that are associated with ageing are discussed.

This Perspective discusses the challenges associated with the prediction of chemical synthesis, in particular the reaction conditions required for organic transformations, and the role of machine-learning approaches in the prediction process.

The history and advancements of gravitational-wave astronomy are reviewed and the future of the field is discussed.

Understanding the behaviour of the machines powered by artificial intelligence that increasingly mediate our social, cultural, economic and political interactions is essential to our ability to control the actions of these intelligent machines, reap their benefits and minimize their harms.

Recent advances and future directions in the use of van der Waals integration beyond two-dimensional materials are reviewed.

Combining mobile phone technologies with infectious disease diagnostics can increase patients’ access to testing and treatment and provide public health authorities with new ways to monitor and control outbreaks of infectious diseases.