Special Feature: Expanding the concepts of cancer metabolism
Beyond the aerobic glycolysis proposed by Otto Warburg in the 1920s, our understanding of cancer metabolism has greatly evolved with the identification of new metabolic pathways with their potential roles and regulatory mechanisms in cancer. Uncovering the extensive network of cancer metabolism during last decades has been enormously accelerated by recent advances in cutting-edge technologies such as multi-omics and 13C metabolic flux analysis (13C-MFA). In this special issue of cancer metabolism, we invited four review articles highlighting the expanding features of cancer metabolism, covering from technological aspects of cancer metabolism research with a practical guide for using 13C-MFA to emerging roles of new metabolic pathways involving vitamin D and non-metabolic functions of metabolic enzymes.
