Supplementary Figure 8: Identification of potential PRDM15 direct transcriptional targets.
From: PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK–ERK signaling
(a,b) Venn diagram depicting the overlap among differentially expressed genes in Prdm15fl/fl versus Prdm15Δ/Δ ESCs and genes bound by PRDM15 on their prompter region (a) or on distal enhancers associated with their respective promoters (b), as identified by ChiA-PET (Nature 504, 306–310, 2013). (c) Snapshots from PRDM15 peak alignment along with those from transcriptional regulators described in Figure 5c.