[go: up one dir, main page]
More Web Proxy on the site http://driver.im/
Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • NEWS AND VIEWS

Tracking humans and microbes

The Human Microbiome Project put the health-associated microbes found in humans on centre stage. The project’s second phase shows how microbial disturbance in disease is linked to host processes.
  1. Verónica Lloréns-Rico

    1. Verónica Lloréns-Rico is at the Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium, and at the VIB Center for Microbiology, Leuven.

    View author publications

    You can also search for this author in PubMed  Google Scholar

  2. Jeroen Raes

    1. Jeroen Raes is at the Rega Institute for Medical Research, KU Leuven, 3000 Leuven, Belgium, and at the VIB Center for Microbiology, Leuven.

    View author publications

    You can also search for this author in PubMed  Google Scholar

Access through your institution
Buy or subscribe

Precision medicine can be defined as “an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person” (see go.nature.com/2wv1ch9). Now, studies from the US National Institutes of Health Integrative Human Microbiome Project (iHMP) provide a resource of microbial and human data tracking the progression of two diseases and pregnancy that will help efforts to understand host-associated microorganisms and their interactions with their human host. The resource will be of great value for aiding the precision-medicine approaches of the future. This work includes three flagship studies: two research papers in Nature, one by Zhou et al.1 and another by Lloyd-Price et al.2 and a paper in Nature Medicine by Fettweis et al.3. There is also a Perspective in Nature by the iHMP Research Network Consortium4, and another research paper in Nature Medicine by Serrano et al.5.

Access options

Access through your institution

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

Nature 569, 632-633 (2019)

doi: https://doi.org/10.1038/d41586-019-01591-y

References

  1. Zhou, W. et al. Nature 569, 663–671 (2019).

    Article  Google Scholar 

  2. Lloyd-Price, J. et al. Nature 569, 655–662 (2019).

    Article  Google Scholar 

  3. Fettweis, J. M. et al. Nature Med. https://doi.org/10.1038/s41591-019-0450-2 (2019).

    Article  Google Scholar 

  4. The Integrative HMP (iHMP) Research Network Consortium. Nature 569, 641–648 (2019).

    Article  Google Scholar 

  5. Serrano, M. G. et al. Nature Med. https://doi.org/10.1038/s41591-019-0465-8 (2019).

    Article  Google Scholar 

  6. Qin, J. et al. Nature 464, 59–65 (2010).

    Article  PubMed  Google Scholar 

  7. The Human Microbiome Project Consortium. Nature 486, 207–214 (2012).

    Article  PubMed  Google Scholar 

  8. Turnbaugh, P. J. et al. Nature 457, 480–484 (2009).

    Article  PubMed  Google Scholar 

  9. Eckburg, P. B. et al. Science 308, 1635–1638 (2005).

    Article  PubMed  Google Scholar 

  10. Costello, E. K. et al. Science 326, 1694–1697 (2009).

    Article  PubMed  Google Scholar 

  11. Vandeputte, D., Tito, R. Y., Vanleeuwen, R., Falony, G. & Raes, J. FEMS Microbiol. Rev. 41, S154–S167 (2017).

    PubMed  Google Scholar 

  12. Gloor, G. B., Macklaim, J. M., Pawlowsky-Glahn, V. & Egozcue, J. J. Front. Microbiol. 8, 2224 (2017).

    Article  PubMed  Google Scholar 

  13. Falony, G. et al. Science 352, 560–564 (2016).

    Article  PubMed  Google Scholar 

  14. Vandeputte, D. et al. Nature 551, 507–511 (2017).

    Article  PubMed  Google Scholar 

  15. He, Y. et al. Nature Med. 24, 1532–1535 (2018).

    Article  PubMed  Google Scholar 

  16. Chen, R. et al. Cell 148, 1293–1307 (2012).

    Article  PubMed  Google Scholar 

  17. Price, N. D. et al. Nature Biotechnol. 35, 747–756 (2017).

    Article  PubMed  Google Scholar 

Download references

Subjects

Latest on:

Nature Careers

Jobs

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing

Search

Advanced search

Quick links