Figure 4
From: A ligand-receptor pair that triggers a non-apoptotic form of programmed cell death
Lack of nuclear fragmentation in SP-induced death in non-neuronal cells. 293T cells transfected with either the empty vector pcDNA3.1 (A,D,G) or NK1R (B,C,E,F,H,I) were immunostained to detect NK1R expression and stained with Hoechst to reveal the nuclear morphology. Note that the rounded cells correspond to the NK1R-expressing ones. 10 μM SP was added for 24 h to cells shown in panels C, F and I. Scale bar, 50 μm