Cyclodextrins and Associated Nanomaterials for Drug and Gene Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".
Deadline for manuscript submissions: closed (15 July 2024) | Viewed by 1610
Special Issue Editors
Interests: nanoparticles; liposomes; solubility improvement; chemotherapeutic delivery
Special Issues, Collections and Topics in MDPI journals
Interests: drug resistance; chemotherapy failure; drug–drug interaction; anticancer drug discovery; novel mechanisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cyclodextrins (CDs) are cyclic oligosaccharides composed of glucopyranose units capable of forming inclusion complexes and clathrates with a variety of hydrophobic drugs and drug carriers. The unique molecular structure and multifunctional properties of cyclodextrins can serve as drug carriers and functionalize nanomaterials for drug delivery applications.
To achieve a sustained release for soluble drugs, hydrophobic cyclodextrins can serve as suitable carriers. By forming ternary drug‒CD‒hydrophilic polymer complexes, the solubilizing and complexing properties of cyclodextrin can be significantly enhanced through the addition of small amounts of hydrophilic polymers.
This Special Issue is dedicated to exploring the pharmaceutical applications of cyclodextrins. It will cover a range of topics including drug delivery systems based on cyclodextrin-inclusion complexes, strategies to enhance drug solubility and bioavailability, formulations for controlled release, and the utilization of cyclodextrins in wound-healing materials. The focus will be on showcasing the potential of cyclodextrins in improving drug stability, targeting specific tissues, and overcoming formulation challenges.
We cordially invite researchers to submit their work to this Special Issue, with the objective of elucidating the various aspects and applications of functionalized cyclodextrins and cyclodextrin-based nanosystems. We welcome all types of articles and encourage the submission of papers and reviews.
Prof. Dr. R. Jayachandra Babu
Dr. Amit K. Tiwari
Guest Editors
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Keywords
- cyclodextrin
- nanoparticle
- nanocarrier
- drug delivery system
- gene delivery system
- inclusion complex
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