Molecular Research on Neuroinflammation and Brain Aging
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".
Deadline for manuscript submissions: 30 March 2025 | Viewed by 958
Special Issue Editor
Interests: neurotoxicology; nutririon; aging; protein aggregates
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aging is an ever-growing global issue as people now tend to live longer. One of the more tragic consequences of expanded longevity is the incidence of neurodegenerative disease present in people who are otherwise healthy. Managing the end-of-life care of those suffering from Alzheimer's disease is a rapidly growing problem that is both stressful and expensive. Specific maladies affecting the aging brain are based and dependent on a range of normal events associated with neurosenescence. One of the main processes characterizing even a healthy aging brain is the gradual malfunctioning of immune function, leading to a chronic state of inflammation that lacks a specific target and is, thus, unproductive. The harmfulness of such random activity in cerebral tissues, is further exacerbated in many neurodegenerative disorders. A contributory factor underlying these events may be related to the brain’s inability to 'forget' a transient inflammatory stimulus, thus failing to fully restore immune activity to the resting state. This Special Issue is devoted to furthering our mechanistic understanding of these progressive changes, thereby allowing for a rational approach to mitigating or delaying their undesirable consequences.
Prof. Dr. Stephen C. Bondy
Guest Editor
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Keywords
- neurotoxicology
- aging
- Alzheimer's disease
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