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The Landauer Principle and Its Implementations in Physics, Chemistry and Biology: Current Status, Critics and Controversies

A special issue of Entropy (ISSN 1099-4300). This special issue belongs to the section "Thermodynamics".

Deadline for manuscript submissions: closed (31 October 2024) | Viewed by 19357

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Dear Colleagues,

The Landauer principle, establishing the energy equivalent of information, has remained as a focus of investigations in the last decade. Although non-equilibrium and quantum extensions of the Landauer principle have been reported, the exact meaning and formulation of the principle remain debatable, and both aspects have been the subject of intense discussion. In its strictest, tightest, and simplest meaning, the Landauer principle states that the erasure of one bit of information requires a minimum energy cost equal to kT ln2, where T is the temperature of a thermal reservoir used in the process and k is Boltzmann’s constant. The Landauer principle was also extended to the transmission of information. Recently, the Landauer principle has been intensively criticized. It has been argued that since it is not independent of the second law of thermodynamics, it is either unnecessary or insufficient as an exorcism of Maxwell’s demon. On the other hand, the Landauer principle enables the “informational” reformulation of thermodynamic laws, thus supporting the information paradigm of physics introduced by John Archibald Wheeler.  Thus, the Landauer principle touches the deepest physical roots of exact sciences.

This Special Issue aims to present different approaches to the implementation of the Landauer principle in physics, chemistry and biology. Submissions addressing engineering applications of the Landauer principle are especially welcome. Review papers are encouraged.

Prof. Dr. Edward Bormashenko
Guest Editor

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Keywords

  • Landauer principle
  • entropy
  • information
  • the second law of thermodynamics

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Published Papers (9 papers)

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8 pages, 275 KiB  
Article
Modified Landauer Principle According to Tsallis Entropy
by Luis Herrera
Entropy 2024, 26(11), 931; https://doi.org/10.3390/e26110931 - 31 Oct 2024
Viewed by 574
Abstract
The Landauer principle establishes a lower bound in the amount of energy that should be dissipated in the erasure of one bit of information. The specific value of this dissipated energy is tightly related to the definition of entropy. In this article, we [...] Read more.
The Landauer principle establishes a lower bound in the amount of energy that should be dissipated in the erasure of one bit of information. The specific value of this dissipated energy is tightly related to the definition of entropy. In this article, we present a generalization of the Landauer principle based on the Tsallis entropy. Some consequences resulting from such a generalization are discussed. These consequences include the modification to the mass ascribed to one bit of information, the generalization of the Landauer principle to the case when the system is embedded in a gravitational field, and the number of bits radiated in the emission of gravitational waves. Full article
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Figure 1
<p><math display="inline"><semantics> <mrow> <mo>Δ</mo> <mi>E</mi> <mo>/</mo> <mi>k</mi> <mi>T</mi> </mrow> </semantics></math> as function of <span class="html-italic">q</span> for the Tsallis entropy.</p>
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16 pages, 2897 KiB  
Article
Elementary Observations: Building Blocks of Physical Information Gain
by J. Gerhard Müller
Entropy 2024, 26(8), 619; https://doi.org/10.3390/e26080619 - 23 Jul 2024
Viewed by 2157
Abstract
In this paper, we are concerned with the process of experimental information gain. Building on previous work, we show that this is a discontinuous process in which the initiating quantum-mechanical matter–instrument interactions are being turned into macroscopically observable events (EOs). In the course [...] Read more.
In this paper, we are concerned with the process of experimental information gain. Building on previous work, we show that this is a discontinuous process in which the initiating quantum-mechanical matter–instrument interactions are being turned into macroscopically observable events (EOs). In the course of time, such EOs evolve into spatio-temporal patterns of EOs, which allow conceivable alternatives of physical explanation to be distinguished. Focusing on the specific case of photon detection, we show that during their lifetimes, EOs proceed through the four phases of initiation, detection, erasure and reset. Once generated, the observational value of EOs can be measured in units of the Planck quantum of physical action h=4.136×1015eVs. Once terminated, each unit of entropy of size kB=8.617×105eV/K, which had been created in the instrument during the observational phase, needs to be removed from the instrument to ready it for a new round of photon detection. This withdrawal of entropy takes place at an energetic cost of at least two units of the Landauer minimum energy bound of ELa=ln2kBTD for each unit of entropy of size kB. Full article
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Figure 1
<p>Situations where matter becomes visible through the interaction with photons.</p>
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<p>(<b>a</b>) Sketch of a double-slit experiment with photons, conducted for increasingly longer periods of time. Photon impacts on the detector screen feature as black dots; (<b>b</b>) developed photographic plates exposed to photons for increasingly longer times. After development of the photographic plates, individual “photon impacts” appear as small, permanently whitened spots, approximating diffraction patterns in the long run.</p>
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<p>Schematic view onto a photo-ionization detector (PID). While the thick red arrow inside the box indicates the internal photoelectron current flow, the thin blue lines on the exterior are electrical wires that allow for current continuity throughout the whole device; <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">R</mi> </mrow> <mrow> <mi mathvariant="bold-italic">D</mi> </mrow> </msub> </mrow> </semantics></math> and <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">C</mi> </mrow> <mrow> <mi mathvariant="bold-italic">D</mi> </mrow> </msub> </mrow> </semantics></math> form an integrator circuit that converts the very short electron pulses into quasi-permanent output voltage readings. The frequency <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">ν</mi> </mrow> <mrow> <mi mathvariant="bold-italic">s</mi> <mi mathvariant="bold-italic">o</mi> <mi mathvariant="bold-italic">u</mi> <mi mathvariant="bold-italic">r</mi> <mi mathvariant="bold-italic">c</mi> <mi mathvariant="bold-italic">e</mi> </mrow> </msub> </mrow> </semantics></math> that is much lower than the inverse transit time through the electrode gap was chosen to conform with the conditions of single-photon detection.</p>
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<p>(<b>a</b>) Observational gain <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">O</mi> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">E</mi> <mi mathvariant="bold-italic">O</mi> </mrow> </msub> <mo>(</mo> <mi mathvariant="bold-italic">L</mi> <mo>,</mo> <msub> <mrow> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">b</mi> </mrow> </msub> <mo>)</mo> </mrow> </semantics></math> as measured in multiples of the Planck constant <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">h</mi> </mrow> </semantics></math> versus the normalized bias potential <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">q</mi> <mrow> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">b</mi> </mrow> </msub> </mrow> <mo>/</mo> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">E</mi> </mrow> <mrow> <mi mathvariant="bold-italic">p</mi> <mi mathvariant="bold-italic">h</mi> </mrow> </msub> </mrow> </mrow> <mo>.</mo> </mrow> </semantics></math> For the sake of good macroscopic observability, a device with a length extension of 300 <math display="inline"><semantics> <mrow> <mi mathvariant="bold-sans-serif">μ</mi> <mi mathvariant="bold">m</mi> <mo>≫</mo> <mi mathvariant="bold-italic">λ</mi> </mrow> </semantics></math> was chosen <math display="inline"><semantics> <mrow> <mo>;</mo> <mfenced separators="|"> <mrow> <mi mathvariant="bold">b</mi> </mrow> </mfenced> </mrow> </semantics></math> electron transit time through the electrode gap as a function of the normalized bias voltage. As shown in <a href="#sec6-entropy-26-00619" class="html-sec">Section 6</a>, the specific choices of <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">q</mi> <msub> <mrow> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">b</mi> </mrow> </msub> <mo>≈</mo> <msub> <mrow> <mi mathvariant="bold-italic">E</mi> </mrow> <mrow> <mi mathvariant="bold-italic">p</mi> <mi mathvariant="bold-italic">h</mi> </mrow> </msub> </mrow> </semantics></math> represent conditions under which optimum observabilty is ensured at minimum entropic cost.</p>
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<p>Pathways of photoelectrons in a band profile picture of a PID: (<b>a</b>) unbiased condition; (<b>b</b>) bias conditions optimally chosen to convert initiating photon energy into the kinetic energy of an emitted photoelectron (see <a href="#entropy-26-00619-f006" class="html-fig">Figure 6</a>).</p>
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<p>(<b>a</b>) Observability <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-sans-serif">Ω</mi> </mrow> <mrow> <mi mathvariant="bold-italic">E</mi> <mi mathvariant="bold-italic">O</mi> </mrow> </msub> </mrow> </semantics></math> as a function of the normalized bias potential <math display="inline"><semantics> <mrow> <mrow> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">q</mi> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">b</mi> </mrow> </msub> </mrow> <mo>/</mo> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">E</mi> </mrow> <mrow> <mi mathvariant="bold-italic">p</mi> <mi mathvariant="bold-italic">h</mi> </mrow> </msub> </mrow> </mrow> </mrow> </semantics></math> with the device size <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">L</mi> </mrow> </semantics></math> as a parameter. The different curves in the inset show the impact of temperature on entropy production; (<b>b</b>) statistical significance <math display="inline"><semantics> <mrow> <msub> <mrow> <mi mathvariant="bold-sans-serif">Σ</mi> </mrow> <mrow> <mi mathvariant="bold-italic">E</mi> <mi mathvariant="bold-italic">O</mi> </mrow> </msub> </mrow> </semantics></math> as a function of the normalized bias potential <math display="inline"><semantics> <mrow> <mrow> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">q</mi> <mi mathvariant="bold-italic">V</mi> </mrow> <mrow> <mi mathvariant="bold-italic">b</mi> </mrow> </msub> </mrow> <mo>/</mo> <mrow> <msub> <mrow> <mi mathvariant="bold-italic">E</mi> </mrow> <mrow> <mi mathvariant="bold-italic">p</mi> <mi mathvariant="bold-italic">h</mi> </mrow> </msub> </mrow> </mrow> </mrow> </semantics></math> and as evaluated for different device sizes <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">L</mi> </mrow> </semantics></math>. For clarity of presentation, the curves in (<b>b</b>) had been slightly offset from each other.</p>
Full article ">Figure 7
<p>Time evolution of an EO as displayed in a band profile picture. Energy flows into the PID are denoted by blue arrows. Red arrows denote the cyclic progress of a photoelectron through the band profile during the four phases of initiation, detection, erasure, and reset. The green arrow indicates the outward flow of signal information when measured in conventional binary information units. Orange arrows denote outward entropy flows into the wider environments of the PID, causing erasure of the intermittently produced information. Reset to the pre-detection state is affected by the PID power supply, causing the electron to be lifted from the Fermi energy of the anode “upstairs” towards the Fermi energy of the cathode.</p>
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<p>Generalized picture of EOs displayed as cyclic processes of initiation, detection, erasure and reset: (<b>a</b>) energy inputs and outputs in the different phases; (<b>b</b>) timing sequence of the four steps in response to energy inputs and outputs.</p>
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<p>Propagation of an electromagnetic wave <math display="inline"><semantics> <mrow> <mi mathvariant="bold-italic">φ</mi> <mo>(</mo> <mi mathvariant="bold-italic">x</mi> <mo>,</mo> <mi mathvariant="bold-italic">t</mi> <mo>)</mo> </mrow> </semantics></math> as visualized as a shift of packages of physical action of the size of a single Planck unit h.</p>
Full article ">
10 pages, 253 KiB  
Article
Landauer Principle and the Second Law in a Relativistic Communication Scenario
by Yuri J. Alvim and Lucas C. Céleri
Entropy 2024, 26(7), 613; https://doi.org/10.3390/e26070613 - 22 Jul 2024
Viewed by 1354
Abstract
The problem of formulating thermodynamics in a relativistic scenario remains unresolved, although many proposals exist in the literature. The challenge arises due to the intrinsic dynamic structure of spacetime as established by the general theory of relativity. With the discovery of the physical [...] Read more.
The problem of formulating thermodynamics in a relativistic scenario remains unresolved, although many proposals exist in the literature. The challenge arises due to the intrinsic dynamic structure of spacetime as established by the general theory of relativity. With the discovery of the physical nature of information, which underpins Landauer’s principle, we believe that information theory should play a role in understanding this problem. In this work, we contribute to this endeavour by considering a relativistic communication task between two partners, Alice and Bob, in a general Lorentzian spacetime. We then assume that the receiver, Bob, reversibly operates a local heat engine powered by information, and seek to determine the maximum amount of work he can extract from this device. As Bob cannot extract work for free, by applying both Landauer’s principle and the second law of thermodynamics, we establish a bound on the energy Bob must spend to acquire the information in the first place. This bound is a function of the spacetime metric and the properties of the communication channel. Full article
18 pages, 957 KiB  
Article
Landauer Bound in the Context of Minimal Physical Principles: Meaning, Experimental Verification, Controversies and Perspectives
by Edward Bormashenko
Entropy 2024, 26(5), 423; https://doi.org/10.3390/e26050423 - 15 May 2024
Cited by 2 | Viewed by 2028
Abstract
The physical roots, interpretation, controversies, and precise meaning of the Landauer principle are surveyed. The Landauer principle is a physical principle defining the lower theoretical limit of energy consumption necessary for computation. It states that an irreversible change in information stored in a [...] Read more.
The physical roots, interpretation, controversies, and precise meaning of the Landauer principle are surveyed. The Landauer principle is a physical principle defining the lower theoretical limit of energy consumption necessary for computation. It states that an irreversible change in information stored in a computer, such as merging two computational paths, dissipates a minimum amount of heat kBTln2 per a bit of information to its surroundings. The Landauer principle is discussed in the context of fundamental physical limiting principles, such as the Abbe diffraction limit, the Margolus–Levitin limit, and the Bekenstein limit. Synthesis of the Landauer bound with the Abbe, Margolus–Levitin, and Bekenstein limits yields the minimal time of computation, which scales as τmin~hkBT. Decreasing the temperature of a thermal bath will decrease the energy consumption of a single computation, but in parallel, it will slow the computation. The Landauer principle bridges John Archibald Wheeler’s “it from bit” paradigm and thermodynamics. Experimental verifications of the Landauer principle are surveyed. The interrelation between thermodynamic and logical irreversibility is addressed. Generalization of the Landauer principle to quantum and non-equilibrium systems is addressed. The Landauer principle represents the powerful heuristic principle bridging physics, information theory, and computer engineering. Full article
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Figure 1
<p>Particle <span class="html-italic">M</span> placed in the twin-well potential is depicted. The position of the particle in the double-well potential will determine the state of the single bit. If the particle is found on the left-hand side of the potential, then we say that the bit is in the “zero” state. If it is found on the right-hand side of the well, then we define that the bit is in the “one” state. The picture is taken from the Bormashenko Ed. “Generalization of the Landauer Principle for Computing Devices Based on Many-Valued Logic” [<a href="#B35-entropy-26-00423" class="html-bibr">35</a>].</p>
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<p>A twin-well system containing particle <span class="html-italic">M</span> illuminated with monochromatic light <math display="inline"><semantics> <mi>ν</mi> </semantics></math> is depicted. The system is in thermal equilibrium with the surrounding <span class="html-italic">T</span>.</p>
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<p>A scheme of the Leo Szilárd minimal engine is depicted. (<b>a</b>) A particle in a box is shown; (<b>b</b>) the partition defines the location of the particle; (<b>c</b>) the particle pushes the piston and the engine performs work; (<b>d</b>) one bit of information is erased.</p>
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12 pages, 3364 KiB  
Article
Events as Elements of Physical Observation: Experimental Evidence
by J. Gerhard Müller
Entropy 2024, 26(3), 255; https://doi.org/10.3390/e26030255 - 13 Mar 2024
Cited by 2 | Viewed by 3046
Abstract
It is argued that all physical knowledge ultimately stems from observation and that the simplest possible observation is that an event has happened at a certain space–time location X=x,t. Considering historic experiments, which have been groundbreaking [...] Read more.
It is argued that all physical knowledge ultimately stems from observation and that the simplest possible observation is that an event has happened at a certain space–time location X=x,t. Considering historic experiments, which have been groundbreaking in the evolution of our modern ideas of matter on the atomic, nuclear, and elementary particle scales, it is shown that such experiments produce as outputs streams of macroscopically observable events which accumulate in the course of time into spatio-temporal patterns of events whose forms allow decisions to be taken concerning conceivable alternatives of explanation. Working towards elucidating the physical and informational characteristics of those elementary observations, we show that these represent hugely amplified images of the initiating micro-events and that the resulting macro-images have a cognitive value of 1 bit and a physical value of Wobs=Eobsτobsh. In this latter equation, Eobs stands for the energy spent in turning the initiating micro-events into macroscopically observable events, τobs for the lifetimes during which the generated events remain macroscopically observable, and h for Planck’s constant. The relative value Gobs=Wobs/h finally represents a measure of amplification that was gained in the observation process. Full article
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Figure 1
<p>(<b>a</b>) Sketch of a Rutherford scattering experiment [<a href="#B1-entropy-26-00255" class="html-bibr">1</a>] which proved the nuclear constitution of atomic matter [<a href="#B3-entropy-26-00255" class="html-bibr">3</a>]. Alpha-particle scattering from a gold foil produces flashes of light on the fluorescent screen (green stars), whose angular distribution can be interpreted as evidence that most of the mass of Au atoms is concentrated in small volumes with linear dimensions on the order of 10<sup>−12</sup> cm [<a href="#B3-entropy-26-00255" class="html-bibr">3</a>]. (<b>b</b>) Angular distribution of light flashes as observed in the original work of Geiger and Marsden in 1913 [<a href="#B1-entropy-26-00255" class="html-bibr">1</a>].</p>
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<p>(<b>a</b>) Matter in the form of photons, electrons, atoms, and molecules is passed through the double-slit arrangements in (<b>a</b>) in one-by-one manner [<a href="#B4-entropy-26-00255" class="html-bibr">4</a>,<a href="#B5-entropy-26-00255" class="html-bibr">5</a>,<a href="#B6-entropy-26-00255" class="html-bibr">6</a>,<a href="#B7-entropy-26-00255" class="html-bibr">7</a>].; (<b>b</b>) After having passed through the double-slit arrangement in (<b>a</b>), the transmitted “particles” interact with a photographic screen on the right, producing macroscopically observable events which accumulate in the form of diffraction patterns after more and more “particles” have been processed through the experimental arrangement in (<b>a</b>). Screen shots at increasingly larger times are shown in subfigures (i); (ii); (iii) [<a href="#B28-entropy-26-00255" class="html-bibr">28</a>].</p>
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<p>(<b>a</b>) α-particle trajectories emerging from an α-particle source immersed inside a cloud chamber [<a href="#B8-entropy-26-00255" class="html-bibr">8</a>,<a href="#B29-entropy-26-00255" class="html-bibr">29</a>]; (<b>b</b>) schematic view of a cloud chamber track of water droplets condensed on water ions formed along the α-particle trajectories [<a href="#B29-entropy-26-00255" class="html-bibr">29</a>].</p>
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<p>(<b>a</b>) A single photon moving from source to fluorescent screen through a narrow slit, either in the form of a particle or in an undulatory manner as a wave; (<b>b</b>) no passage of a photon during the observational time period. Elementary observations of this kind produce an information gain equivalent to one binary digit or bit.</p>
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<p>Time-resolved sketch of Rutherford scattering process; sequential steps of information gathering and reset.</p>
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<p>Time-resolved sketch of elementary particle detection in cloud chamber; sequential steps of information gathering and reset.</p>
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<p>(<b>a</b>) Cohesion energy (blue) and internal pressure of water droplets (red) as a function of drop radius. The development of an inside-oriented pressure resulting from the desire to minimize the numbers of weakly bound H<sub>2</sub>O molecules on surfaces is shown in the inset. (<b>b</b>) Cohesion energy (blue), evaporative lifetime (red), and observational value (magenta) as a function of drop radius. The colored areas denote the phases of initial growth (red) and of long-lived and macroscopically observable drops that delineate α-particle trajectories.</p>
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14 pages, 527 KiB  
Article
On the Precise Link between Energy and Information
by Cameron Witkowski, Stephen Brown and Kevin Truong
Entropy 2024, 26(3), 203; https://doi.org/10.3390/e26030203 - 27 Feb 2024
Cited by 2 | Viewed by 2227
Abstract
We present a modified version of the Szilard engine, demonstrating that an explicit measurement procedure is entirely unnecessary for its operation. By considering our modified engine, we are able to provide a new interpretation of Landauer’s original argument for the cost of erasure. [...] Read more.
We present a modified version of the Szilard engine, demonstrating that an explicit measurement procedure is entirely unnecessary for its operation. By considering our modified engine, we are able to provide a new interpretation of Landauer’s original argument for the cost of erasure. From this view, we demonstrate that a reset operation is strictly impossible in a dynamical system with only conservative forces. Then, we prove that approaching a reset yields an unavoidable instability at the reset point. Finally, we present an original proof of Landauer’s principle that is completely independent from the Second Law of thermodynamics. Full article
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<p>A depiction of the classic Szilard engine.</p>
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<p>Our modified Szilard engine.</p>
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<p>A potential energy function, <math display="inline"><semantics> <mrow> <mi>V</mi> <mo>(</mo> <mi>x</mi> <mo>)</mo> </mrow> </semantics></math>, one might use to attempt a reset procedure using conservative forces.</p>
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<p>An energy landscape one might implement to perform a reset with minimal energy loss.</p>
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<p>A graphical representation of the transition probabilities described by Equations (<a href="#FD27-entropy-26-00203" class="html-disp-formula">27</a>)–(29).</p>
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11 pages, 319 KiB  
Article
Thermodynamical versus Logical Irreversibility: A Concrete Objection to Landauer’s Principle
by Didier Lairez
Entropy 2023, 25(8), 1155; https://doi.org/10.3390/e25081155 - 1 Aug 2023
Cited by 3 | Viewed by 1713
Abstract
Landauer’s principle states that the logical irreversibility of an operation, such as erasing one bit, whatever its physical implementation, necessarily implies its thermodynamical irreversibility. In this paper, a very simple counterexample of physical implementation (that uses a two-to-one relation between logic and thermodynamic [...] Read more.
Landauer’s principle states that the logical irreversibility of an operation, such as erasing one bit, whatever its physical implementation, necessarily implies its thermodynamical irreversibility. In this paper, a very simple counterexample of physical implementation (that uses a two-to-one relation between logic and thermodynamic states) is given that allows one bit to be erased in a thermodynamical quasistatic manner (i.e., one that may tend to be reversible if slowed down enough). Full article
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Figure 1
<p>Expansion of a unit amount of gas from volume <span class="html-italic">V</span> (state A) to <math display="inline"><semantics><mrow><mn>2</mn><mi>V</mi></mrow></semantics></math> (state B) at the same temperature <span class="html-italic">T</span> (in joules). (1) Monothermal expansion with a piston (top): the gas produces work <span class="html-italic">W</span> and pumps heat <span class="html-italic">Q</span>. (2) Adiabatic free expansion (middle): no heat and no work are exchanged with the surroundings. In both cases the cycle is closed using the same restoring process (bottom). In the first case, the net energy cost <math display="inline"><semantics><mrow><msub><mi>E</mi><mrow><mi>cost</mi></mrow></msub><mo>=</mo><mo>−</mo><mi>Q</mi></mrow></semantics></math> of a cycle can be as small as desired (quasistatic, Equation (<a href="#FD3-entropy-25-01155" class="html-disp-formula">3</a>)). In the second case, it has a lower limit of <math display="inline"><semantics><mrow><mi>T</mi><mo form="prefix">ln</mo><mn>2</mn></mrow></semantics></math> (Equation (<a href="#FD4-entropy-25-01155" class="html-disp-formula">4</a>)).</p>
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<p>Landauer’s functional procedure to physically implement the RESET TO 0 (ERASE) logical operation by the means of a thermodynamical bistable potential with a tunable barrier and a bias. Here, the bit is initially set to 1 but the same procedure would apply if the was were set to 0.</p>
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<p>Two-to-one implementation of a bit: quasistatic isothermal compression/expansion of a gas is performed with a transmission of gear ratio 2 (crank–pulley/crankshaft–pulley). The two stable positions of the crank (to which are assigned bit values 0 and 1) correspond to a single stable position of the piston.</p>
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<p>The gear ratio <span class="html-italic">r</span> can be small enough so that thermal fluctuations of the gas below the piston permit the crank-angle (<math display="inline"><semantics><mi>ϕ</mi></semantics></math>) to be in any position. This soft potential well determines a third state (S for “standard”) for a virgin bit.</p>
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12 pages, 914 KiB  
Article
Dissipation during the Gating Cycle of the Bacterial Mechanosensitive Ion Channel Approaches the Landauer Limit
by Uğur Çetiner, Oren Raz, Madolyn Britt and Sergei Sukharev
Entropy 2023, 25(5), 779; https://doi.org/10.3390/e25050779 - 10 May 2023
Cited by 1 | Viewed by 1970
Abstract
The Landauer principle sets a thermodynamic bound of kBT ln 2 on the energetic cost of erasing each bit of information. It holds for any memory device, regardless of its physical implementation. It was recently shown that carefully built artificial devices [...] Read more.
The Landauer principle sets a thermodynamic bound of kBT ln 2 on the energetic cost of erasing each bit of information. It holds for any memory device, regardless of its physical implementation. It was recently shown that carefully built artificial devices can attain this bound. In contrast, biological computation-like processes, e.g., DNA replication, transcription and translation use an order of magnitude more than their Landauer minimum. Here, we show that reaching the Landauer bound is nevertheless possible with biological devices. This is achieved using a mechanosensitive channel of small conductance (MscS) from E. coli as a memory bit. MscS is a fast-acting osmolyte release valve adjusting turgor pressure inside the cell. Our patch-clamp experiments and data analysis demonstrate that under a slow switching regime, the heat dissipation in the course of tension-driven gating transitions in MscS closely approaches its Landauer limit. We discuss the biological implications of this physical trait. Full article
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Figure 1

Figure 1
<p>(<b>Left</b>) Schematic description of the experimental apparatus. The Giga-ohm resistance of the piece of <span class="html-italic">E. coli</span>’s inner membrane with naturally embedded mechanosensitive ion channels (MscS) seals the micro-pipette, and provides electrical isolation between its inner and outer sides. Application of suction to the glass pipette stretches the curved membrane according to Laplace’s law. This tension can change the state of the MscS channels, generating detectable conducting pathways between the two electrodes. (<b>Right</b>) The state of the channel (<math display="inline"><semantics> <mi>σ</mi> </semantics></math>) as a function of the membrane tension (<math display="inline"><semantics> <mi>γ</mi> </semantics></math>). A single channel event is shown. The state of the channel can be monitored with a high temporal resolution. The transition from the closed (0) state to the open state (1) occurs at <math display="inline"><semantics> <msub> <mi>γ</mi> <mi>open</mi> </msub> </semantics></math>.</p>
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<p>(<b>A</b>): Restore to open protocol. When unperturbed, the channels naturally occupy the low energy configuration, which is the closed state. In the first part of the protocol, the tension was quickly (<math display="inline"><semantics> <mrow> <mo>∼</mo> <mn>0.25</mn> <mspace width="4pt"/> </mrow> </semantics></math>s) increased to the midpoint tension <math display="inline"><semantics> <msub> <mi>γ</mi> <mrow> <mn>0.5</mn> </mrow> </msub> </semantics></math><math display="inline"><semantics> <mrow> <mo>(</mo> <mn>1.9</mn> <mspace width="4pt"/> <msub> <mi>k</mi> <mi>B</mi> </msub> <mi>T</mi> <mo>/</mo> </mrow> </semantics></math>nm<math display="inline"><semantics> <msup> <mrow/> <mn>2</mn> </msup> </semantics></math>) [<a href="#B39-entropy-25-00779" class="html-bibr">39</a>] at which the probability of finding a channel in the open or closed state was <math display="inline"><semantics> <mrow> <mn>0.5</mn> </mrow> </semantics></math>. The tension was kept fixed at <math display="inline"><semantics> <msub> <mi>γ</mi> <mrow> <mn>0.5</mn> </mrow> </msub> </semantics></math> for 3 s to let the channels thermalize at this specific tension value. In the final setup, the tension was increased from <math display="inline"><semantics> <msub> <mi>γ</mi> <mrow> <mn>0.5</mn> </mrow> </msub> </semantics></math> to <math display="inline"><semantics> <mrow> <msub> <mi>γ</mi> <mi>τ</mi> </msub> <mo>=</mo> <msub> <mi>γ</mi> <mrow> <mi>m</mi> <mi>a</mi> <mi>x</mi> </mrow> </msub> </mrow> </semantics></math> (<math display="inline"><semantics> <mrow> <mn>3</mn> <mspace width="4pt"/> <msub> <mi>k</mi> <mi>B</mi> </msub> <mi>T</mi> <mo>/</mo> </mrow> </semantics></math>nm<math display="inline"><semantics> <msup> <mrow/> <mn>2</mn> </msup> </semantics></math>) in 0.25, 1, 5 and 10 s. Regardless of the initial state of the channels, at the end of the final step, all channels were forced to be in the open state. (<b>B</b>): An experimental trace obtained from the restore to open protocol. In the final step, the tension was increased from <math display="inline"><semantics> <msub> <mi>γ</mi> <mrow> <mn>0.5</mn> </mrow> </msub> </semantics></math> to <math display="inline"><semantics> <msub> <mi>γ</mi> <mi>τ</mi> </msub> </semantics></math> in 1 s. The inset shows the single-channel gating events at a higher magnification during the restore to one operation.</p>
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<p>The average dissipated heat as a function of the “restore to open” operation rate. As the channels are restored to the open state slower and slower (the duration increases), the average heat dissipated decreases, but it is always above Landauer’s limit of <math display="inline"><semantics> <mrow> <mi>l</mi> <mi>n</mi> <mn>2</mn> </mrow> </semantics></math>. Under sustained mechanical stimuli, the MscS channels inactivate wherein they enter a non-conductive and tension-insensitive state. Therefore, the slowest experimentally achievable erasure duration was limited to 10 s after which the channels display significant inactivation. A Markov model of two-state MscS has been also simulated using QUBexpress software with different rates of the “restore to open” protocol (red data points). The simulation results not only agree with the experimental counterpart but also attain the same limit of <math display="inline"><semantics> <mrow> <mi>l</mi> <mi>n</mi> <mn>2</mn> </mrow> </semantics></math>. The simulation parameters are provided in <a href="#sec5-entropy-25-00779" class="html-sec">Section 5</a>. The inset shows the histograms of heat distributions from which the averages are obtained.</p>
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<p>An Edge detector program (<a href="http://cismm.web.unc.edu/resources/tutorials/edge-detector-1d-tutorial/" target="_blank">http://cismm.web.unc.edu/resources/tutorials/edge-detector-1d-tutorial/</a> (accessed on 19 May 2020)) was employed to detect the single channel events.</p>
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Review

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12 pages, 298 KiB  
Review
Landauer Bound and Continuous Phase Transitions
by Maria Cristina Diamantini
Entropy 2023, 25(7), 984; https://doi.org/10.3390/e25070984 - 28 Jun 2023
Viewed by 1614
Abstract
In this review, we establish a relation between information erasure and continuous phase transitions. The order parameter, which characterizes these transitions, measures the order of the systems. It varies between 0, when the system is completely disordered, and 1, when the system is [...] Read more.
In this review, we establish a relation between information erasure and continuous phase transitions. The order parameter, which characterizes these transitions, measures the order of the systems. It varies between 0, when the system is completely disordered, and 1, when the system is completely ordered. This ordering process can be seen as information erasure by resetting a certain number of bits to a standard value. The thermodynamic entropy in the partially ordered phase is given by the information-theoretic expression for the generalized Landauer bound in terms of error probability. We will demonstrate this for the Hopfield neural network model of associative memory, where the Landauer bound sets a lower limit for the work associated with ‘remembering’ rather than ‘forgetting’. Using the relation between the Landauer bound and continuous phase transition, we will be able to extend the bound to analog computing systems. In the case of the erasure of an analog variable, the entropy production per degree of freedom is given by the logarithm of the configurational volume measured in units of its minimal quantum. Full article
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