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Applied Sciences
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Recent Developments and Emerging Trends in Dental Diseases and Dental...
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Recent Developments and Emerging Trends in Dental Diseases and Dental Materials

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 657

Special Issue Editor

Dr. Felice Femiano

E-Mail Website
Guest Editor
Multidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy
Interests: dentinal hypersensitivity; diode laser in dentistry; conservative dental restoration
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The introduction of increasingly high-performance dental materials with highly bioactive and biofunctional characteristics makes these products increasingly interactive with the dental tissues of the host. These activities can sometimes cause dental pathologies that could be difficult to resolve.

The objective of this Special Issue is to present research on the use of most current dental materials to prepare clinicians on the correct choice of material personalized for the patient to avoid unwanted effects and to not only establish the correct protocols for the use of dental materials but also be aware of suitable procedures to deal with and resolve adverse events.

Dr. Felice Femiano
Guest Editor

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • dental materials
  • dental diseases
  • oral health
  • biocompatibility
  • dentistry
  • restorative materials

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Published Papers (1 paper)

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Research

12 pages, 4121 KiB  
Article
The Impact of Silver Nanoparticles on Dentinal Tubule Penetration of Endodontic Bioceramic Sealer
by Sundus Bukhary, Sarah Alkahtany, Amal Almohaimede, Nourah Alkhayatt, Shahad Alsulaiman and Salma Alohali
Appl. Sci. 2024, 14(24), 11639; https://doi.org/10.3390/app142411639 - 12 Dec 2024
Viewed by 521
Abstract
The impact of adding silver nanoparticles (AgNPs) to bioceramic (BC) sealer on their ability to penetrate dentinal tubules is still unknown. Thus, this confocal laser scanning microscopic (CLSM) study aimed to assess the extent of dentinal tubule penetration of BC sealer (TotalFill® [...] Read more.
The impact of adding silver nanoparticles (AgNPs) to bioceramic (BC) sealer on their ability to penetrate dentinal tubules is still unknown. Thus, this confocal laser scanning microscopic (CLSM) study aimed to assess the extent of dentinal tubule penetration of BC sealer (TotalFill® Hiflow BC Sealer™, FKG, Switzerland) with and without AgNPs using the single-cone (SC) technique and the continuous-wave condensation (CWC) technique. AgNPs alone as well as in a mixture with the BC sealer were characterized using scanning electron microscopy and transmission electron microscopy. Single-rooted extracted human teeth (N = 100) were selected and prepared, and then divided into four groups (n = 25). Group 1 (BC/SC): BC sealer obturated with the SC technique. Group 2 (BC+AgNPs/SC): BC sealer with AgNPs obturated with the SC technique. Group 3 (BC/CWC): BC Sealer obturated with the CWC technique. Group 4 (BC+AgNPs/CWC): BC Sealer with AgNPs obturated with the CWC technique. After 2 weeks, roots were horizontally sectioned to obtain 1 mm thick dentin slices that were evaluated with CLSM. Sealer dentinal tubule penetration area and the maximum depth of penetration were measured. Data were analyzed with one-way ANOVA and the Tukey multiple comparison tests (p ≤ 0.05). The characterization process demonstrated a spherical-shaped nanoparticles without obvious agglomeration. The results showed that Group 2 (BC+AgNPs/SC) significantly demonstrated the highest mean tubular penetration depth, while group 3 (BC/CWC) had the lowest mean depth. Group 2 (BC+AgNPs/SC) exhibited the significantly highest mean value for the total area of penetration. However, groups 1 (BC/SC) and 3 (BC/CWC) exhibited the lowest mean value of total penetration area, with no statistically significant difference. The integration of AgNPs with BC sealer markedly enhanced penetration into dentinal tubules. The SC technique demonstrated superior penetration relative to the CWC technique. Full article
(This article belongs to the Special Issue Recent Developments and Emerging Trends in Dental Diseases and Dental Materials)
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Figure 1

Figure 1
<p>(<b>A</b>) Maximum penetration depth measurement; (<b>B</b>) total area of sealer penetration measurement. All images are shown at 5× magnification.</p> Full article ">Figure 2
<p>(<b>A</b>) SEM image of AgNPs illustrating the spherical shape and size range (×200,000); (<b>B</b>) TEM image of AgNPs illustrates the spherical-shaped particles, as well as the absence of nanoparticles agglomeration (×300,000); (<b>C</b>) TEM image of AgNPs mixed with bioceramic sealer demonstrates the spherical shape of AgNPs precipitated within the structure of the sealer, with no obvious agglomeration (×150,000).</p> Full article ">Figure 3
<p>The bar chart shows the mean ± standard deviations of the maximum depth of penetration (<b>A</b>) and total area of sealer penetration (<b>B</b>) of the experimental groups.</p> Full article ">Figure 4
<p>Representative CLSM images showing the penetrability of the experimental sealers into dentinal tubules. (<b>A1</b>–<b>A4</b>) represent the BC+AgNPs/SC group, showing heavy and homogenous fluorescence, indicating great sealer penetration with long tags from the canal lumen toward the cementodentinal junction. (<b>B1</b>–<b>B4</b>) represent the BC+AgNPs/CWC group, showing sealer penetration through the dentinal tubules with long tags. (<b>C1</b>–<b>C4</b>) represent the BC/SC group, showing minimal sealer penetration into dentinal tubules with short tags. (<b>D1</b>–<b>D4</b>) represent the BC/CWC group, denoting hardly noticeable fluorescence, indicating minimal sealer penetration into dentinal tubules. All images are shown at 10× magnification. All bars represent 200 µm.</p> Full article ">
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