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KEGG   Talpa occidentalis (Iberian mole): 119232025
Entry
119232025         CDS       T07495                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04064  NF-kappa B signaling pathway
tod04072  Phospholipase D signaling pathway
tod04151  PI3K-Akt signaling pathway
tod04380  Osteoclast differentiation
tod04611  Platelet activation
tod04613  Neutrophil extracellular trap formation
tod04625  C-type lectin receptor signaling pathway
tod04650  Natural killer cell mediated cytotoxicity
tod04662  B cell receptor signaling pathway
tod04664  Fc epsilon RI signaling pathway
tod04666  Fc gamma R-mediated phagocytosis
tod05152  Tuberculosis
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05168  Herpes simplex virus 1 infection
tod05169  Epstein-Barr virus infection
tod05171  Coronavirus disease - COVID-19
tod05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    119232025 (SYK)
   04072 Phospholipase D signaling pathway
    119232025 (SYK)
   04151 PI3K-Akt signaling pathway
    119232025 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    119232025 (SYK)
   04613 Neutrophil extracellular trap formation
    119232025 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    119232025 (SYK)
   04662 B cell receptor signaling pathway
    119232025 (SYK)
   04664 Fc epsilon RI signaling pathway
    119232025 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    119232025 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119232025 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    119232025 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    119232025 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119232025 (SYK)
   05169 Epstein-Barr virus infection
    119232025 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    119232025 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119232025 (SYK)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     119232025 (SYK)
Protein kinases [BR:tod01001]
 Non-receptor tyrosine kinases
  SYK family
   119232025 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 DUF7063 Kdo ABC1 RIO1
Other DBs
NCBI-GeneID: 119232025
NCBI-ProteinID: XP_037349800
Position
Unknown
AA seq 628 aa
MADVANHLPYFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYT
IERELNGTYAIAGGRTHGSPAELCLYHSQESDGLVCLLKKPFNRPSGVQPKTGPFEDLKE
NLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLIG
SKINGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLVEHYS
YKPDGLLRVLTVPCQKIGAQAGHINFGTRPQLPSSHPAAWTAGGIISRIKSYSFPKPGQR
KPPSPGNRPESTFNPYEPDRGPWAAEREVQREALPMDTEVYESPYADPEEIRPKEVYLDR
KLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQL
DNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEE
CNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYY
KFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPREMYELMNL
CWTYDVENRPGFVAVELRLRNYYYDVVN
NT seq 1887 nt   +upstreamnt  +downstreamnt
atggctgacgtcgccaaccacctgccctatttcttcggcaacatcacccgggaagaggca
gaggactacctggtgcagggtggcatgagtgatgggctctatctactacgccagagccgc
aattacctgggtggcttcgccctgtctgtggcacacgggaggaaggcacaccactatacc
atcgagcgggagctgaacgggacctacgccattgccgggggcaggacccatggcagccct
gccgaactctgcctctatcactcccaggagtcagatggcctcgtctgcctcctcaagaag
cccttcaaccggccatctggggtgcaacccaagactggaccctttgaagacctcaaggaa
aacctcatcagggaatatgtgaagcagacctggaacctgcagggtcaagctctggaacag
gccatcatcagccagaaacctcagttggagaagctcattgccaccacagcccatgaaaaa
atgccctggttccatggaaaaatctctcgggatgaatctgagcaaattgtcctaatagga
tcaaagataaatggaaaattcttgatcagggccagggacaacaacgggtcctacgctctg
tgcctactgcatgaagggaaggtgctgcactaccgcatcgataaggacaaaacggggaag
ctctccatccccgatggaaagaagtttgacacgctctggcagctagttgagcattattct
tataaaccagatggtttgttgagagttctcaccgtcccatgtcaaaaaattggtgcgcaa
gcaggacatattaattttggaactcgtccccaactcccaagctcccatcctgcggcctgg
acagcgggtggaataatctcaagaatcaaatcatactccttccccaagcctggccaaaga
aagcccccatcccccgggaaccgaccggagagcactttcaacccctacgagccagaccga
gggccctgggctgcggaacgagaggtccagagagaagccttgcccatggacactgaggtg
tacgaaagcccctatgcagaccctgaggagatcaggcccaaggaggtctacctggaccgg
aagctgctgaccctggaggataaggagctgggctctggtaattttgggactgtgaagaag
ggctactaccagatgaagaaagtcgtaaaaacagtggctgtgaaaattctgaaaaatgag
gccaatgaccctgctcttaaagacgagttactagcagaagccaatgtcatgcagcagctg
gacaacccgtacattgtgcgcatgattgggatttgcgaagccgagtcctggatgctggtg
atggagatggcagaactcggtcccctcaataaatacttacagcagaacaggcatgtcaag
gataagaacatcatagagctggttcatcaggtttctatgggaatgaaatacttggaggag
tgcaattttgtgcacagagatctggctgcaaggaatgttttgctagttactcaacattat
gccaagatcagtgattttggactttccaaagcacttcgtgctgatgaaaactactacaag
gcacagacccacgggaagtggccagttaagtggtacgcaccagagtgcatcaactactac
aagttctccagcaagagcgacgtctggagcttcggagtgctcatgtgggaagcgttttcc
tacgggcagaagccttaccgaggaatgaaaggaagtgaagtttccgccatgctggagaaa
ggagagaggatgggctgccccgcaggctgtccaagggagatgtacgagctgatgaacctg
tgctggacatatgatgtggagaacaggcctggatttgtagcagtggaacttcggttacga
aattactactacgatgtggttaactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (7)   
   Pfam (7)   
All databases (38)   

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