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KEGG   Pteronotus mesoamericanus (Parnell's mustached bat): 129082351
Entry
129082351         CDS       T09558                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
ppam  Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam04064  NF-kappa B signaling pathway
ppam04072  Phospholipase D signaling pathway
ppam04151  PI3K-Akt signaling pathway
ppam04380  Osteoclast differentiation
ppam04611  Platelet activation
ppam04613  Neutrophil extracellular trap formation
ppam04625  C-type lectin receptor signaling pathway
ppam04650  Natural killer cell mediated cytotoxicity
ppam04662  B cell receptor signaling pathway
ppam04664  Fc epsilon RI signaling pathway
ppam04666  Fc gamma R-mediated phagocytosis
ppam05152  Tuberculosis
ppam05167  Kaposi sarcoma-associated herpesvirus infection
ppam05168  Herpes simplex virus 1 infection
ppam05169  Epstein-Barr virus infection
ppam05171  Coronavirus disease - COVID-19
ppam05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ppam00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    129082351 (SYK)
   04072 Phospholipase D signaling pathway
    129082351 (SYK)
   04151 PI3K-Akt signaling pathway
    129082351 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    129082351 (SYK)
   04613 Neutrophil extracellular trap formation
    129082351 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    129082351 (SYK)
   04662 B cell receptor signaling pathway
    129082351 (SYK)
   04664 Fc epsilon RI signaling pathway
    129082351 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    129082351 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    129082351 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    129082351 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    129082351 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    129082351 (SYK)
   05169 Epstein-Barr virus infection
    129082351 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    129082351 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppam01001]
    129082351 (SYK)
Enzymes [BR:ppam01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     129082351 (SYK)
Protein kinases [BR:ppam01001]
 Non-receptor tyrosine kinases
  SYK family
   129082351 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo DUF7145 DUF7063 ABC1 SH2_1 RIO1
Other DBs
NCBI-GeneID: 129082351
NCBI-ProteinID: XP_054444015
Position
Unknown
AA seq 627 aa
MAAGMADHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHY
TIERELNGTYAIAGGRAHASPAELCHYHSQESDGLVCLLKKPFNRPPGVQPKTGPFEDLK
ENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRDESEQIVLI
GSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLVEHY
SYKPDGLLRVLTVPCQKIGRQTGNGPQLPSAHPATWSPSGIISRFASRSFLKPAHKKASS
SQGNRPESSMTFNPYEPDPGPWTADRETQREALPMDTGVYESPYADPEEIRPKEVYLDRK
LLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQLD
NPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEEC
NFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYK
FSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPPGCPREMYDLMNLC
WTYDVESRPGFAAVELRLRNYYYDVVN
NT seq 1884 nt   +upstreamnt  +downstreamnt
atggctgcaggcatggctgaccacctgcccttcttctttggcaacatcactcgggaggag
gctgaggactacttggtccaaggtggcatgagtgatgggctctacctgctgcgccagagc
cgcaattacctgggcggcttcgctctgtcagtggcacacgggcgcaaagcgcaccactac
accattgagcgagagctgaatgggacctatgccatcgcgggtggcagggcacatgccagc
cctgctgagctctgccattaccactcccaggagtcagatggcctcgtctgcctcctcaag
aaacccttcaaccggccacctggggtgcagcccaagactggaccctttgaggacctgaag
gagaacctcatccgggagtatgtgaagcagacctggaacctgcagggccaagctctggag
caggccattatcagccagaagcctcagctggagaagctgatcgccaccacagcccacgag
aaaatgccctggttccacggaaaaatctctcgggatgaatctgagcaaattgtcctgata
ggatcaaagacaaatggaaaatttttgatcagggccagggacaacaacgggtcctttgcc
ctatgcctgctacatgagggcaaagtgctgcactaccgtattgacaaggacaagacgggg
aagctctccatcccggatggcaagaagttcgacacactctggcagctagttgaacattat
tcgtataaaccagatggtttgttaagagttcttactgttccatgtcaaaaaattggccgg
caaacaggaaatggtccacaacttccaagtgcccatccagcgacttggtcaccaagtgga
ataatctcaagattcgcatcacgctccttcttaaagcctgcccacaaaaaggcctcctca
tctcaggggaaccgtccagagagctccatgacgttcaatccctatgagccagatccaggg
ccctggactgcagatagagaaacccagagggaagccttgccaatggacacaggagtgtat
gaaagcccctatgcggaccctgaggagatcaggcccaaggaggtctacctggaccggaag
ctgctgaccctggaagacaaagaactgggctctggtaactttggcactgtgaagaagggc
tactaccagatgaaaaaagttgtgaaaacagtggctgtgaaaatcctgaaaaatgaggcc
aatgacccagctctgaaggatgagctgttagcagaagccaacgtcatgcagcagctggac
aacccttacattgtgcgcatgatcgggatttgtgaagctgagtcctggatgctggttatg
gagatggcagaacttggtccactcaataaatatttacagcagaacaggcatgtcaaagat
aagaacatcatagagctggttcatcaggtttctatgggaatgaagtatttggaggagtgc
aattttgtgcatagagatctggctgcaagaaacgtattgctggttactcaacattatgcc
aagatcagtgattttggactttccaaagcacttcgtgctgatgaaaactactacaaggcc
cagacccatgggaagtggcccgtgaagtggtatgctccagagtgcatcaactactacaag
ttttccagcaagagtgacgtctggagcttcggggtgttaatgtgggaagcgttttcctat
gggcagaagccgtatcgggggatgaaaggaagtgaagtttctgctatgctggagaaagga
gagaggatggggtgccctccagggtgtcccagggagatgtatgatctgatgaacctgtgc
tggacatatgacgtggagagccggcccgggttcgcagctgtggaactgcggctgcgcaat
tactactatgacgtggtgaactaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (9)   
   Pfam (9)   
All databases (38)   

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